Clinical Results of Definitive Chemoradiotherapy for Patients With Synchronous Head and Neck Squamous Cell Carcinoma and Esophageal Cancer

2011 ◽  
Vol 34 (4) ◽  
pp. 362-366 ◽  
Author(s):  
Makoto Shinoto ◽  
Yoshiyuki Shioyama ◽  
Tomonari Sasaki ◽  
Katsumasa Nakamura ◽  
Hiroki Ohura ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Cancer ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Clinical Results ◽  
Neck Squamous Cell Carcinoma ◽  
Definitive Chemoradiotherapy

scholarly journals Characteristics of esophageal cancer in patients with head and neck squamous cell carcinoma

2021 ◽  
Vol 10 (5) ◽  
pp. 1954-1961
Author(s):  
Lei Wang ◽  
Wenjing Pang ◽  
Kun Zhou ◽  
Lei Li ◽  
Feng Wang ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Cancer ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma

Positron emission tomography in surveillance of head and neck squamous cell carcinoma after definitive chemoradiotherapy

Head & Neck ◽  
2009 ◽  
Vol 31 (4) ◽  
pp. 442-451 ◽  
Author(s):  
Yi-Fen Wang ◽  
Ren-Shyan Liu ◽  
Pen-Yuan Chu ◽  
Feng-Chi Chang ◽  
Shyh-Kuan Tai ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Emission Tomography ◽  
Definitive Chemoradiotherapy ◽  
Positron Emission

scholarly journals Deleted in Esophageal Cancer 1(DEC1) Is Down-Regulated and Contributes to Migration in Head and Neck Squamous Cell Carcinoma Cell Lines

ORL ◽  
2011 ◽  
Vol 73 (1) ◽  
pp. 17-23 ◽  
Author(s):  
Yasuomi Kunimoto ◽  
Seiji Nakano ◽  
Hideyuki Kataoka ◽  
Yutaka Shimada ◽  
Mitsuo Oshimura ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Cancer ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Cell Lines ◽  
Squamous Cell ◽  
Carcinoma Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Squamous Cell Carcinoma Cell ◽  
Carcinoma Cell Lines

scholarly journals Association Between Cancer Cachexia and Prognosis in Patients with Head and Neck Squamous Cell Carcinoma Who Received Chemoradiotherapy

2021 ◽  
Author(s):  
Naomi Hayashi ◽  
Yasuyoshi Sato ◽  
Yu Fujiwara ◽  
Naoki Fukuda ◽  
Xiaofei Wang ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Prognostic Factors ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Cancer Cachexia ◽  
Neck Squamous Cell Carcinoma ◽  
Adjuvant Chemoradiotherapy ◽  
Adjuvant Setting ◽  
Definitive Chemoradiotherapy

Abstract Objectives: This retrospective observational study is conducted to evaluate the association between cancer cachexia and prognosis in head and neck cancer patients treated with chemoradiotherapy using skeletal muscle mass index at the level of the third lumbar vertebra with computed tomography.Methods: Two hundred forty-two patients were enrolled and categorized into the following four groups based on cancer cachexia criteria and treatment setting: definitive chemoradiotherapy with cachexia, definitive chemoradiotherapy without cachexia, adjuvant chemoradiotherapy with cachexia, and adjuvant chemoradiotherapy without cachexia. Progression-free survival (PFS) and overall survival (OS) between cachexia and non-cachexia groups were compared by treatment setting using the long-rank test. Prognostic factors were evaluated using the Cox proportional hazards model.Results: Fifty patients were diagnosed with cancer cachexia (20.7%). In the definitive setting, both PFS and OS were significantly shorter in the cachexia group (median PFS, 15.5 months vs. not reached, p < 0.01; median OS, 48.4 months vs. not reached. p < 0.01). Conversely, there was no significant difference between the two groups in the adjuvant setting. UICC Stage IV, base of albumin of <4, and cachexia were significant poor prognostic factors in the definitive setting. However, no prognostic factors were detected in the adjuvant setting.Conclusion: Cancer cachexia was negatively related with prognosis in patients with head and neck squamous cell carcinoma who received definitive chemoradiotherapy. Nutritional intervention during chemoradiotherapy may improve survival in these patients. Further research is warranted.

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