Solitary Spindle Cell Xanthogranuloma Mimicking a Spitz Nevus

Spitz nevi (epithelioid and spindle-cell nevi) are a special group of melanocytic neoplasms with a specific clinical, dermatoscopic and histological picture. There are typical and atypical Spitz nevus. The typical Spitz nevus is more common in pediatric practice and has a benign course. Of particular interest are atypical forms that combine the characteristics of a typical Spitz nevus and melanoma. The article presents an analysis of the clinical picture, dermatoscopic, immunohistochemical, histological and genetic characteristics in various forms of Spitz nevus. The existing classification according to the metastasis risk degree is presented. The last recommendations on the tactics of managing patients with this nosology are discussed with examples of original observations.

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Spitz nevus (large spindle cell and/or epithelioid cell nevus)

Virchows Archiv A Pathological Anatomy and Histopathology ◽

10.1007/bf00784346 ◽

1989 ◽

Vol 415 (2) ◽

pp. 97-101 ◽

Cited By ~ 29

Author(s):

Yves M�rot ◽

Edgar Frenk

Keyword(s):

Spindle Cell ◽

Epithelioid Cell ◽

Spitz Nevus

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A Case of Combined Nevus: Compound Nevus and Spindle Cell Spitz Nevus

The Journal of Dermatology ◽

10.1111/j.1346-8138.2000.tb02157.x ◽

2000 ◽

Vol 27 (4) ◽

pp. 233-237 ◽

Cited By ~ 12

Author(s):

Zhao-hui Jin ◽

Masanobu Kumakiri ◽

Hisaya Ishida ◽

Shoichi Kinebuchi

Keyword(s):

Spindle Cell ◽

Spitz Nevus

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Clinical Review of 247 Case Records of Spitz Nevus (Epithelioid Cell and/or Spindle Cell Nevus)

Dermatology ◽

10.1159/000246051 ◽

1997 ◽

Vol 194 (1) ◽

pp. 20-25 ◽

Cited By ~ 44

Author(s):

V. Dal Pozzo ◽

C. Benelli ◽

L. Restano ◽

R. Gianotti ◽

B.M. Cesana

Keyword(s):

Clinical Review ◽

Spindle Cell ◽

Epithelioid Cell ◽

Spitz Nevus

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Spindle Cell and Epithelioid Cell Nevi with Atypia and Metastasis (Malignant Spitz Nevus)

The American Journal of Surgical Pathology ◽

10.1097/00000478-198911000-00003 ◽

1989 ◽

Vol 13 (11) ◽

pp. 931-939 ◽

Cited By ~ 186

Author(s):

Kathleen J. Smith ◽

Terry L. Barrett ◽

Henry G. Skelton ◽

George P. Lupton ◽

James H. Graham

Keyword(s):

Spindle Cell ◽

Epithelioid Cell ◽

Spitz Nevus

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Angiomatoid Spitz Nevus

Revista da Sociedade Portuguesa de Dermatologia e Venereologia ◽

10.29021/spdv.78.4.1245 ◽

2020 ◽

Vol 78 (4) ◽

pp. 377-379

Author(s):

Jorge Lopes ◽

David Afonso-João ◽

Diogo Teixeira ◽

Armando Baptista

Keyword(s):

Spindle Cell ◽

Distant Metastases ◽

Rare Tumor ◽

Fibrous Stroma ◽

Spitz Nevus ◽

Small Vessels ◽

Long Term Follow Up ◽

Vascular Component

Angiomatoid Spitz nevus is a rare tumor that combines the classic aspects of Spitz nevus with a prominent vascular component. Clinically, it presents as a pink or brownish papule, usually solitary, in the extremities of young adults. On histology, it is characterized by a proliferation of epithelioid or spindle cell melanocytes embedded in a fibrous stroma, where a dense proliferation of small vessels is evident. The differential diagnosis with malignant melanoma can be difficult, particularly with the desmoplastic variant or with those with marked regression. Its behavior is benign, as suggested by the absence of local recurrences or distant metastases during long-term follow-up.

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Ultrastructure of mesotheliomas

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100110775 ◽

1984 ◽

Vol 42 ◽

pp. 98-101

Author(s):

Irving Dardick

Keyword(s):

Electron Microscopy ◽

Latent Period ◽

Spindle Cell ◽

Spindle Cell Sarcoma ◽

Metastatic Adenocarcinoma ◽

Cell Sarcoma ◽

Cytological Features ◽

Industrial Use ◽

Degree Of Differentiation

With the extensive industrial use of asbestos in this century and the long latent period (20-50 years) between exposure and tumor presentation, the incidence of malignant mesothelioma is now increasing. Thus, surgical pathologists are more frequently faced with the dilemma of differentiating mesothelioma from metastatic adenocarcinoma and spindle-cell sarcoma involving serosal surfaces. Electron microscopy is amodality useful in clarifying this problem.In utilizing ultrastructural features in the diagnosis of mesothelioma, it is essential to appreciate that the classification of this tumor reflects a variety of morphologic forms of differing biologic behavior (Table 1). Furthermore, with the variable histology and degree of differentiation in mesotheliomas it might be expected that the ultrastructure of such tumors also reflects a range of cytological features. Such is the case.

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Inflammatory Myofibroblastic Tumour in Antimesenteric Border of Descending Colon of Children: A Case Report

Journal of Paediatric Surgeons of Bangladesh ◽

10.3329/jpsb.v3i1.23908 ◽

2015 ◽

Vol 3 (1) ◽

pp. 47-50

Author(s):

Shahnoor Islam ◽

AKM Amirul Morshed ◽

Afiqul Islam

Keyword(s):

Soft Tissue ◽

Spindle Cell ◽

Inflammatory Myofibroblastic Tumour ◽

Pathological Findings ◽

Soft Tissue Lesion ◽

Soft Tissue Tumours ◽

Inflammatory Pseudotumour ◽

Erythrocyte Sedimentation ◽

Antimesenteric Border

Inflammatory myofibroblastic tumour (IMT) occurring at intraabdominal sites in children has rarely been described. Inflammatory pseudotumour is a soft tissue lesion that may be confused with a sarcoma. It is abbreviated as IMT. Inflammatory myofibroblastic tumour, also known as soft tissue tumours, atypical fibromyxoid tumours, pseudosarcomatous fibromyxoid tumour, plasma cell granuloma, pseudosarcomatous myofibrotic proliferation, post-operative spindle cell nodules. In this paper, we describe a case of inflammatory myofibroblastic tumour (IMT) with an unusual constellation of clinical, pathological findings. A 10-year-old girl had an 7-cm intraabdominal mass accompanied by severe anemia, fever, constipation, weight loss, thrombocytosis, elevated erythrocyte sedimentation rate. Laparotomy was performed. The final pathologic diagnosis was IMT. At the most recent follow up (12months) after excision of the tumour, the patient was symptom-free and there was no evidence of tumour recurrence.J. Paediatr. Surg. Bangladesh 3(1): 47-50, 2012 (January)

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