Skin pH, Atopic Dermatitis, and Filaggrin Mutations

Dermatitis ◽  
2014 ◽  
Vol 25 (3) ◽  
pp. 127-129 ◽  
Author(s):  
Josefine Bandier ◽  
Jeanne Duus Johansen ◽  
Lars Jelstrup Petersen ◽  
Berit Christina Carlsen
Keyword(s):  
Atopic Dermatitis ◽  
Skin Ph

Atopic dermatitis: evaluation of the influence of physiotherapy on the barrier function of the skin and the severity of the course of dermatosis in children

2020 ◽  
pp. 43-51
Author(s):  
T. V. Koroleva ◽  
I. I. Ivanova ◽  
E. V. Filatova
Keyword(s):  
Atopic Dermatitis ◽  
Laser Radiation ◽  
Drug Treatment ◽  
Barrier Function ◽  
Polarized Light ◽  
Physiological Factors ◽  
Skin Ph ◽  
Maximum Decrease ◽  
Positive Effect ◽  
Ph Metry

The article presents data on the dynamics of indicators reflecting the barrier function of the skin: pH-metry, TEWA-metry and corneometry, under the infl uence of physiological factors. It was shown that under the influence of polarized light, laser radiation and hydrotherapy, in combination with drug treatment, the maximum decrease in the Scorad index is determined by 4,5 times. Moreover, each of the applied factors had a positive effect.

scholarly journals Skin pH Is the Master Switch of Kallikrein 5-Mediated Skin Barrier Destruction in a Murine Atopic Dermatitis Model

2016 ◽  
Vol 136 (1) ◽  
pp. 127-135 ◽  
Author(s):  
Hyosun Jang ◽  
Akira Matsuda ◽  
Kyungsook Jung ◽  
Kaoru Karasawa ◽  
Kenshiro Matsuda ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Skin Barrier ◽  
Skin Ph

scholarly journals Measurement of epidermal hydration and skin ph in infants with atopic dermatitis before and after a bath

2021 ◽  
Vol 22 (4) ◽  
pp. 326
Author(s):  
Pirabakaran Sivanesan ◽  
Thulasi Weerasinghe ◽  
Kavindra Nanayakkara ◽  
Praneeth Ratnayake ◽  
Sriyani Samaraweera ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Skin Ph ◽  
Before And After

Vitamin D shows in vivo efficacy in a placebo-controlled, double-blinded, randomised clinical trial on canine atopic dermatitis

2018 ◽  
Vol 182 (14) ◽  
pp. 406-406 ◽  
Author(s):  
Christoph J Klinger ◽  
Stefan Hobi ◽  
Cornelia Johansen ◽  
Hans-Joachim Koch ◽  
Karin Weber ◽  
...  
Keyword(s):  
Vitamin D ◽  
Atopic Dermatitis ◽  
Water Loss ◽  
Clinical Signs ◽  
Group Versus ◽  
Clinical Effects ◽  
Vitamin D Metabolites ◽  
Canine Atopic Dermatitis ◽  
Skin Ph ◽  
Double Blinded

Atopic dermatitis (AD) in dogs is among the most common skin diseases in small animal practice. It is an inflammatory disease based on a genetic predisposition to develop hypersensitivity against environmental and food allergens and typical clinical signs up exposure. Treatment sometimes can be difficult and associated with adverse effects. Previous studies evaluating cholecalciferol as treatment for human AD have shown promising results. With canine AD being a good animal model for its human counterpart, it was hypothesised that cholecalciferol might have beneficial clinical effects in dogs, too. In this randomised, placebo-controlled, double-blinded eight-week cross-over study, 23 client-owned dogs received either systemic cholecalciferol (n=16), a vitamin D receptor analogue (n=8) or placebo (n=13). Blood samples for ionised calcium were obtained regularly during the study, and Canine Atopic Dermatitis Extent and Severity Index and pruritus scores, blood levels of vitamin D metabolites, measurements of skin pH and transepidermal water loss were determined before and after. Pruritus and lesion scores decreased significantly in the cholecalciferol group versus placebo. No differences in water loss or skin pH were observed. An increase in serum 25-hydroxycholecalciferol strongly correlated with a reduction in pruritus. Systemic cholecalciferol may be a viable treatment option for canine AD.

scholarly journals Skin pH–dependent Staphylococcus aureus abundance as predictor for increasing atopic dermatitis severity

Allergy ◽  
2020 ◽  
Vol 75 (11) ◽  
pp. 2888-2898 ◽  
Author(s):  
Claudia Hülpüsch ◽  
Karolina Tremmel ◽  
Gertrud Hammel ◽  
Madhumita Bhattacharyya ◽  
Amedeo Tomassi ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Atopic Dermatitis ◽  
Atopic Dermatitis Severity ◽  
Skin Ph ◽  
Ph Dependent

scholarly journals THE FUNCTIONAL STATUS OF THE SKIN BARRIER IN CHILDREN WITH ATOPIC DERMATITIS

2013 ◽  
Vol 10 (1) ◽  
pp. 52-57
Author(s):  
E T Kindeeva ◽  
E E Varlamov ◽  
A N Pampura
Keyword(s):  
Staphylococcus Aureus ◽  
Atopic Dermatitis ◽  
Topical Therapy ◽  
Skin Barrier ◽  
Specific Ige ◽  
Transepidermal Water Loss ◽  
Severe Atopic Dermatitis ◽  
Skin Ph ◽  
Skin Colonization

Introduction. One of the factors in the pathogenesis of atopic dermatitis is a dysfunction of the skin barrier. Background. To reveal the features of the barrier function of the skin in children with atopic dermatitis by measuring transepidermal water loss (TEWL) and the pH of the skin. Methods. The study included 98 children with atopic dermatitis. All patients measurement was performed by TEWL (Tewameter TM 300, Multi Probe Adapter MPA 5/9, Courage + Khazaka) and the pH of the skin (Skin-pHMeter, Multi Probe Adapter MPA 5/9, Courage + Khazaka). Results. TEWL value was significantly higher in children with severe atopic dermatitis (p=0,00001), in children up to 3 years (p=0,002), in patients with skin colonization of Staphylococcus aureus (p=0,006) and with specific IgE to staphylococcal enterotoxins. Skin pH was significantly higher in children with severe atopic dermatitis (p=0,0001), and in children under the age of 3 years (p=0,04). Conclusion. The determination of the level of TEWL and skin pH to assess the degree of inflammation activity in atopic dermatitis and to justify use of topical therapy, aimed to restoring the epidermal barrier of the skin at children with atopic dermatitis, is substantiated.

scholarly journals Exposure to cold airflow alters skin pH and epidermal filaggrin degradation products in children with atopic dermatitis

2020 ◽  
Vol 69 (3) ◽  
pp. 429-436
Author(s):  
Minyoung Jung ◽  
Insung Kim ◽  
Ji Young Lee ◽  
Hyun Mi Kim ◽  
Mijeong Kwon ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Degradation Products ◽  
Skin Ph ◽  
Exposure To Cold
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