scholarly journals Retained Placenta Creta After Selective Fetal Reduction in Twin Pregnancy

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Weiran Zheng ◽  
Xinrui Yang ◽  
Yuchun Zhu ◽  
Jie Yan ◽  
Huixia Yang
1994 ◽  
Vol 142 (2) ◽  
pp. 261-265 ◽  
Author(s):  
M R Johnson ◽  
A A Abbas ◽  
A C J Allman ◽  
K H Nicolaides ◽  
S L Lightman

Abstract The factors that determine the circulating levels of relaxin during pregnancy have been investigated by comparing the plasma levels of relaxin throughout pregnancy in women who became pregnant spontaneously (singleton, n=240) or following superovulation (singleton and multifetal pregnancies (two to ten conceptuses), n=83). Some of the women with multifetal pregnancies underwent selective fetal reduction to twin pregnancies. Relaxin levels were higher at 7–34 weeks of gestation in singleton pregnancies achieved following superovulation when compared with levels in spontaneously conceived singleton pregnancies (P<0·05–0·001). In samples obtained between 10 and 12 weeks of gestation (before fetal reduction for the multifetal pregnancies), plasma relaxin levels correlated with fetal number (r=0·526, P=0·0001). Reduction in fetal number to a twin pregnancy did not alter relaxin levels. These data suggest that the circulating levels of relaxin throughout pregnancy are determined during the cycle of conception by gonadotrophin stimulation, and within the first 10 weeks of pregnancy by the luteotrophic stimulus from the conceptus. Furthermore, once corpus luteum synthesis of relaxin is established, then reduction in the luteotrophic stimulus does not appear to affect it. Journal of Endocrinology (1994) 142, 261–265


2017 ◽  
Vol 9 (3) ◽  
pp. 277-279
Author(s):  
Vineet Mishra ◽  
Rohina Aggarwal ◽  
Sumesh Choudhary ◽  
Himani Agarwal

ABSTRACT Background The incidence of conjoined twins is rare. In early pregnancy, transvaginal ultrasound may facilitate diagnosis and prompt intervention can be done. Case Report A 35 years old patient with history of infertility for 17 years conceived after In vitro fertilization–embryo transfer with donor oocytes due to ovarian factor; three embryos were transferred. Transvaginal sonography was done on 21st day after transfer and it revealed three gestational sacs with fetal pole in all the sacs. Repeat TVS done on 65th day post embryo transfer revealed one gestational sac with single live embryo, second sac with two embryos joined at thorax and abdomen with a common heart, and two heads. Couple was then counseled for fetal reduction in view of expected poor outcome of conjoined twins. Selective fetal reduction was done at 12 weeks gestation with intra-cardiac potassium chloride administration. Pregnancy is now ongoing with an apparently normal live singleton fetus. Conclusion When conjoined twins are detected early, fetal reduction is a good modality of management. These pregnancies are associated with severe complications, maternal and fetal morbidity and mortality. Hence, the sooner the fetal reduction is, the better the management of conjoined twins. How to cite this article Choudhary S, Mishra V, Aggarwal R, Agarwal H. Selective Fetal Reduction of Conjoined Twins in Twin Pregnancy. J South Asian Feder Obst Gynae 2017;9(3):277-279.


2005 ◽  
Vol 83 (5) ◽  
pp. S12
Author(s):  
M. Mitwally ◽  
H. Albuarki ◽  
M.H. Fakih ◽  
F.N. Shamma ◽  
J. Ayers ◽  
...  

2020 ◽  
Author(s):  
Shiri Shinar ◽  
Swati Agrawal ◽  
Darine El‐Chaâr ◽  
Nimrah Abbasi ◽  
Robert Beecroft ◽  
...  

2015 ◽  
Vol 30 (8) ◽  
pp. 1807-1812 ◽  
Author(s):  
L. van de Mheen ◽  
S.M.P. Everwijn ◽  
M.F.C.M. Knapen ◽  
M.C. Haak ◽  
M.A.J. Engels ◽  
...  

2000 ◽  
Vol 164 (1) ◽  
pp. 7-11 ◽  
Author(s):  
O Ogueh ◽  
AP Hawkins ◽  
A Abbas ◽  
GD Carter ◽  
KH Nicolaides ◽  
...  

The aim of the study was to investigate maternal thyroid function in pregnancy by monitoring the circulating concentrations of thyroid stimulating hormone (TSH), free thyroxine (fT(4)) and human chorionic gonadotrophin (hCG) in multifetal pregnancies before and after embryo reduction. We studied two groups of women: group 1 comprised singleton (n=12) and twin (n=12) pregnancies achieved after superovulation and in vitro fertilisation and embryo transfer (IVF-ET), and group 2 were multifetal pregnancies (n=39) undergoing selective fetal reduction to twin pregnancies. Blood samples were obtained initially at 10-12 weeks gestation (before fetal reduction) and then 4 and 8 weeks afterwards. Before fetal reduction, the circulating concentrations of fT(4) in multifetal pregnancies were significantly greater than those in singleton or twin pregnancies (singleton, mean 16.49 pmol/l (interquartile range 14.09-18.13 pmol/l); twins, 15.84 (15.36-16.95 pmol/l); multifetal, 21.08 (16. 64-26.29 pmol/l); P<0.005 for singleton and twins), and in a multiple regression analysis, fT(4) was significantly related to the number of fetuses (F=23.739, P=0.0001), but not to hCG. After fetal reduction to twins, the circulating concentrations of fT(4) in multifetal pregnancies decreased progressively towards those in control twin pregnancies, but remained significantly greater at both 4 (P=0.003) and 8 weeks (P=0.050). This pattern of change in the concentrations of fT(4) is similar to, but lags behind, that of hCG, which attains twin levels 4 weeks after fetal reduction. This may represent a delayed thyroid response to the decreasing concentrations of hCG, but the alternative is that the maternal thyroid function is controlled by a fetal factor in addition to hCG.


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