Subjective sleep disturbance increases the nocturnal blood pressure level and attenuates the correlation with target-organ damage

2011 ◽  
Vol 29 (2) ◽  
pp. 242-250 ◽  
Author(s):  
Léon HG Henskens ◽  
Martin PJ van Boxtel ◽  
Abraham A Kroon ◽  
Robert J van Oostenbrugge ◽  
Jan Lodder ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Sleep Disturbance ◽  
Target Organ Damage ◽  
Blood Pressure Level ◽  
Organ Damage ◽  
Pressure Level ◽  
Target Organ ◽  
Subjective Sleep ◽  
Nocturnal Blood Pressure

Is blood pressure load associated, independently of blood pressure level, with target organ damage?

2013 ◽  
Vol 31 (9) ◽  
pp. 1812-1818 ◽  
Author(s):  
Ming Liu ◽  
Yan Li ◽  
Fang-Fei Wei ◽  
Lu Zhang ◽  
Jing-Ling Han ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Target Organ Damage ◽  
Blood Pressure Level ◽  
Organ Damage ◽  
Pressure Level ◽  
Target Organ ◽  
Pressure Load ◽  
Blood Pressure Load

600 IS BLOOD PRESSURE LOAD ASSOCIATED, INDEPENDENTLY OF BLOOD PRESSURE LEVEL, WITH TARGET ORGAN DAMAGE?

2012 ◽  
Vol 30 ◽  
pp. e175-e176
Author(s):  
Ming Liu ◽  
Fang-Fei Wei ◽  
FA-Hong Li ◽  
Ji-Guang Wang ◽  
Yan Li
Keyword(s):  
Blood Pressure ◽  
Target Organ Damage ◽  
Blood Pressure Level ◽  
Organ Damage ◽  
Pressure Level ◽  
Target Organ ◽  
Pressure Load ◽  
Blood Pressure Load

scholarly journals Nocturnal Non-dipping Blood Pressure Profile in Black Normotensives Is Associated with Cardiac Target Organ Damage

2016 ◽  
Vol 26 (3) ◽  
pp. 279 ◽  
Author(s):  
Kenechukwu Mezue ◽  
Godsent Isiguzo ◽  
Chichi Madu ◽  
Geoffrey Nwuruku ◽  
Janani Rangaswami ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Left Ventricular ◽  
Target Organ ◽  
Volume Index ◽  
Left Ventricular Geometry ◽  
Nocturnal Blood Pressure ◽  
Significant Difference

<p><strong>Purpose: </strong>A non-dipping pattern of nocturnal blood pressure in hypertensive patients is an established predictor of cardiovascular risk, especially in Blacks. However, data on non-dipping normotensives and cardiovascular risk in this population is sparse. In this study, we aim to determine if a non-dipping profile in a cohort of Black normotensives is associated with cardiac target organ damage. <strong></strong></p><p><strong>Methods: </strong>We studied ambulatory blood pressure patterns in 43 normotensive Black patients of Caribbean origin and classified their profiles as dippers (DP) and nondippers (NDP) based on their nocturnal blood pressure profiles. Cardiac target organ damage was estimated from 2-D echocardiogram. </p><p><strong>Results: </strong>The mean age of the cohort was 52 years. Both groups were similar with respect to baseline age, sex, weight, height, body mass index and daytime ambulatory BP. There was a statistically significant difference in nocturnal blood pressure between DP and NDP groups (112 ± 7/64 ± 2 mm Hg vs 117 ± 3/69 ± 2 mm Hg, P=.004). The NDP cohort showed evidence of cardiovascular target damage on echocardiography with a significantly increased relative wall thickness (.35 ± .07cm vs .42 ± .05 cm, P=.001), left ventricular mass index (95 ± 14 vs 105 ± 14 g/m2, P=.018) and left atrial volume index (26 ± 3.5 vs. 30 ± 3.4, P=.001). Left ventricular geometry in the non-dippers also showed increased concentric remodeling, concentric and eccentric hypertrophy. </p><p><strong>Conclusions: </strong>Our study demonstrates that nocturnal non-dipping of blood pressure in normotensive Blacks of Caribbean origin may be associated with cardiovascular end organ damage thereby providing new surveillance and therapeutic targets. <em>Ethn Dis.</em>2016;26(3):279-284; doi:10.18865/ed.26.3.279 </p><br /><p><strong> </strong></p>

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