Irrigation therapy for acute rhinosinusitis: possible complications

Irrigation therapy is widely used in clinical practice for the treatment of acute rhinosinusitis. One of the methods of irrigation therapy is the Proetz method. This method has many contraindications and is associated with the development of a number of complications, which are not always taken into account by otorhinolaryngologists. We present a number of observations of complications associated with an uncontrolled pressure decrease in the nasal cavity and paranasal sinuses.

Maximizing Condensate Production Opportunities in a Giant Stacked Reservoir-Case Study

This paper addresses the opportunities of maximizing the condensate production in a giant Recycle Gas-Condensate Reservoir in UAE. The condensate reservoir is producing many years under recycling mode to maintain the pressure and maximize the gas condensate recovery. The producers and injector wells are in a line drive pattern where the injected fluid is lean gas to maintain 100% VRR. The condensate production declined through the years due to gradual pressure decrease as well as injected lean gas/N2 breakthrough. Several studies were done to increase condensate recovery and extend gas production plateau.

Pluto’s Atmosphere in Plateau Phase Since 2015 from a Stellar Occultation at Devasthal

A stellar occultation by Pluto was observed on 2020 June 6 with the 1.3 m and 3.6 m telescopes located at Devasthal, Nainital, India, using imaging systems in the I and H bands, respectively. From this event, we derive a surface pressure for Pluto’s atmosphere of p surf = 12.23 − 0.38 + 0.65 μbar. This shows that Pluto’s atmosphere has been in a plateau phase since mid-2015, a result which is in excellent agreement with the Pluto volatile transport model of Meza et al. This value does not support the pressure decrease reported by independent teams, based on occultations observed in 2018 and 2019 by Young et al. and Arimatsu et al., respectively.

Wellbore Integrity: An Integrated Experimental and Numerical Study to Investigate Pore Pressure Variation during Cement Hardening under Downhole Conditions

Summary Understanding the cement hardening process and determining the development of the state of stress in the cement under specific downhole conditions are challenging but fundamental requirements to perform an accurate prediction of wellbore integrity. As an essential component of the state of stress, the temporal variation of cement pore pressure is a critical factor that affects the occurrence of cement failure. In this study, we present a novel laboratory setup to measure the cement pore pressure variation during hardening under representative downhole conditions, including the pressure, temperature, and water exchange between the cement and formation. The pore pressure measurements are further incorporated with a staged finite element analysis (FEA) approach to investigate the state of stress development during cement hardening and to evaluate cement failure under different operations and after different wait-on-cement (WOC) periods. The laboratory measurements show that the external water supply from the formation significantly impedes the pore pressure drop in the cement. The numerical results indicate that the accelerated pore pressure decrease obtained without considering downhole conditions elevates the contact pressure at the cement-formation interfaces significantly and moderately increases the von Mises stress in the cement. The numerical results further predict that the accelerated pore pressure decrease leads to an overestimation of shear failure during pressure testing and steamflooding operations but an underestimation of debonding failure during severe fluid loss and injection-related cooling processes. Based on the results of the integrated laboratory and numerical approach, qualitative and quantitative suggestions are provided for field operations to inhibit wellbore integrity risk during the wellbore life cycle.

Use of Fenoldopam in Children with Congenital Heart Disease to Decrease Fluid Balance: A Retrospective, Descriptive Study and Insights into Predictors of Decreased Fluid Balance

This retrospective study aimed to determine if fenoldopam is associated with a decrease in fluid balance and to define the factors that may promote this in children with a history of congenital heart disease at the cardiac intensive care unit (CICU). Patients cared from January 2014 to December 2018 in the CICU were reviewed, and those on fenoldopam infusion were identified. Patient cohort data included demographics, clinical information, laboratory results, hemodynamic and urine output measurements, and information regarding fenoldopam infusion were compared between those with and without decrease in fluid balance. Forty-six patients were identified. Patients received a starting dose of fenoldopam of 0.2 mcg/kg/h, a maximum dose of 0.3 mcg/kg/h, and duration of 64 hours. Over the 4-hour study period, statistically significant change was noted in systolic pressure (decrease of 5.4%; p < 0.001), diastolic pressure (decrease of 3.5%; p = 0.01), fluid balance, and urine output (decrease of 1.3%; p = 0.027). In the cohort, 34 patients (74%) had a decrease in fluid balance, 18 (39%) had an increase in urine output, and 25 (54%) had a decrease in fluid input after the initiation of fenoldopam. Patients that had a decrease in fluid balance tended to have a higher blood urea nitrogen level at the time of fenoldopam initiation. Fenoldopam was associated with decrease in fluid balance and fluid input, but not associated with an increase in urine output. The identification of factors that can decrease fluid balance may help identify those patients who can be benefited with this treatment.