Abundance and multimodal visibility of soft drusen in early age-related macular degeneration

Retina ◽  
2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Ling Chen ◽  
Jeffrey D. Messinger ◽  
Kenneth R. Sloan ◽  
Jessica Wong ◽  
Austin Roorda ◽  
...  
2006 ◽  
Vol 83 (4) ◽  
pp. 880-886 ◽  
Author(s):  
Chung-Jung Chiu ◽  
Larry D Hubbard ◽  
Jane Armstrong ◽  
Gail Rogers ◽  
Paul F Jacques ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Young Ho Kim ◽  
Boram Lee ◽  
Edward Kang ◽  
Jaeryung Oh

AbstractChoroidal changes have been suggested to be involved in the pathophysiology of both age-related macular degeneration (AMD) and pachychoroid spectrum diseases (PSD). To find out the choroidal characteristics of each disease groups, various groups of AMD and PSD were classified into several clusters according to choroidal profiles based on subfoveal choroidal thickness (CT), peripapillary CT, the ratio of subfoveal CT to peripapillary CT and age. We retrospectively analyzed 661 eyes, including 190 normal controls and 471 with AMD or PSDs. In the AMD groups, eyes with soft drusen or reticular pseudodrusen were belonged to the same cluster as those with classic exudative AMD (all p < 0.001). However, eyes with pachydrusen were not clustered with eyes from other AMD groups; instead, they were classified in the same cluster as eyes from the PSD group (all p < 0.001). In the PSD group, eyes with pachychoroid neovasculopathy were grouped in the same cluster of those with polypoidal choroidal vasculopathy (p < 0.001). The cluster analysis based on the CT profiles, including subfoveal CT, peripapillary CT, and their ratio, revealed a clustering pattern of eyes with AMD and PSDs. These findings support the suggestion that pachydrusen has the common pathogenesis as PSD.


2004 ◽  
Vol 109 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Changzheng Chen ◽  
Lezheng Wu ◽  
Dezheng Wu ◽  
Shizhou Huang ◽  
Feng Wen ◽  
...  

PLoS ONE ◽  
2020 ◽  
Vol 15 (10) ◽  
pp. e0240357
Author(s):  
Maho Sato ◽  
Sakiko Minami ◽  
Norihiro Nagai ◽  
Misa Suzuki ◽  
Toshihide Kurihara ◽  
...  

2019 ◽  
Vol 60 (5) ◽  
pp. 1581 ◽  
Author(s):  
Caroline Brandl ◽  
Christiane Brücklmayer ◽  
Felix Günther ◽  
Martina E. Zimmermann ◽  
Helmut Küchenhoff ◽  
...  

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