Purpose: To evaluate glistening and long-term stability of five commercially available intraocular lenses. Methods: This experimental study evaluated the SN60WF (Alcon), XY1 (Hoya), NS-60YG (NIDEK), ZCB00V (Johnson & Johnson Vision) and AN6KA (Kowa) intraocular lenses. To generate glistenings, intraocular lenses were immersed in physiological saline at 50°C for 2 h, then left in situ at 35°C and removed at regular intervals over 24 h. Stability of the intraocular lens material was assessed by immersing intraocular lenses into vials of purified water placed at 100°C for 115 days, which simulated 20-year ageing. Gas chromatography–mass spectrometry was used to detect leached compounds. Results: Almost no glistenings were observed for the AN6KA. Glistenings were observed in the remaining intraocular lenses after 3 h. The number of glistenings gradually disappeared by 6 h for all intraocular lenses except SN60WF (12 h). Only the NS-60YG and ZCB00V intraocular lenses had no changes in weight or dimensions. Gas chromatography–mass spectrometry detected phenethyl alcohol in XY1 and SN60WF, 2-phenoxyethanol in AN6K and no compounds in the remaining intraocular lenses. A peak shift due to the carbonyl group between 1600 and 1700 cm−1 was detected for the SN60WF and AN6K intraocular lenses only. Conclusion: SN60WF had the most numerous glistenings that resolved over a longer duration. The long-term stability test confirmed elution of the intraocular lens material–derived compounds and signs of degradation for the XY1, SN60WF and AN6K intraocular lenses. NS-60YG and ZCB00V showed no signs of deterioration due to ageing. Differing manufacturing methods likely play a role in the stability of intraocular lenses.
Long-term stability of intraocular lens optic capture after femtosecond laser capsulotomy in traumatic cataract with coexisting subluxation and posterior capsule dehiscence
