Monitoring Corneal Densities Following Primary Pterygium Excision With Adjuvant Topical Mitomycin-C Application—An Observational Study of Corneal Scar Changes

Cornea ◽  
2015 ◽  
Vol 34 (5) ◽  
pp. 530-534 ◽  
Author(s):  
Ka Wai Kam ◽  
Michael W. Belin ◽  
Alvin L. Young
Keyword(s):  
Observational Study ◽  
Mitomycin C ◽  
Corneal Scar ◽  
Pterygium Excision ◽  
Primary Pterygium

Prospective Study on the Safety and Efficacy of Combined Conjunctival Rotational Autograft With Intraoperative 0.02% Mitomycin C in Primary Pterygium Excision

Cornea ◽  
2009 ◽  
Vol 28 (2) ◽  
pp. 166-169 ◽  
Author(s):  
Alvin L Young ◽  
Patrick M K Tam ◽  
Gloria Y S Leung ◽  
Lulu L Cheng ◽  
Philip T H Lam ◽  
...  
Keyword(s):  
Prospective Study ◽  
Mitomycin C ◽  
Safety And Efficacy ◽  
Pterygium Excision ◽  
Primary Pterygium

scholarly journals The Role of Using Motorized Diamond Burr Polisher Instrument in Minimizing the Recurrent Rate of Pterygium Excision

2020 ◽  
pp. 129-136
Author(s):  
Sakar Abdulkarim Nidhamalddin
Keyword(s):  
Diamond Polishing ◽  
Corneal Scar ◽  
Group A ◽  
Iop Measurement ◽  
The Mean ◽  
Diamond Burr ◽  
Pterygium Excision ◽  
The Difference ◽  
Group B ◽  
Primary Pterygium

To compare the effects of using motorized diamond burr polisher in pterygium excision versus manual polishing of the corneoscleral bed in reducing the recurrent rate. A prospective, comparative and interventional study of 90 consecutive patients with different grads of primary pterygium, who underwent pterygium excision at Shahid Aso teaching eye hospital in Sulaimani city, between August 2018 till September 2019, which was performed by single surgeon. In group A (45) eyes polishing of the corneoscleral bed done using motorized diamond polishing burr, and in group B (45) eyes using manual crescent blade for polishing. Recurrent rate was evaluated after about (8±2) months postoperatively. Ethical consideration of the risks and the benefits of the procedure was observed for each individual patient. A 90 patients with the mean age of group A (48.84±12.7) years and group B (49.67±12.3) years, complained of different grads of primary pterygium, group A had 31(68.9%) male and 14(31.1%) female, while group B had 22(48.9%) male and 23(51.1%) female. Each individual factors like age, gender, visual acuity, BCVA pre and postoperatively, IOP measurement, dryness of the eye and risk factors like smoking and UV exposure affecting the recurrence were assessed. In both groups the main indication for surgery was sign of irritation. The mean surgical time was calculated and the difference between two groups were significant. After follow-up of average six months the outcomes and recurrent rate were checked, recurrent rate was in group A 1(2.2%) while in group B was 6(13.3%) patients. it significantly decreased. Corneal scar happens in only 1(2.2%) case of group A while in 11(24.4%) cases in group B, Corneal scar was statistically significant. In both groups the change of BCVA was significant but the visual change was more significant in group A in compare to group B. Motorized diamond burr is a safe instrument for polishing the cornea during pterygium excision, it is easy to handle, low price, need lesser operative time, its effect on recurrence postoperatively is significant and beside it leaves lesser corneal scar and early visual recovery postoperatively.   

scholarly journals Comparing Adjuvant Beta Radiation, Mitomycin C, and Conjunctival Autograft in Primary Pterygium Treatment, a Three-year Follow-up Study

2021 ◽  
Vol 14 (1) ◽  
pp. 82-87
Author(s):  
Khalil M. Al-Salem ◽  
Ahmad T.S. Saif ◽  
Passant S. Saif
Keyword(s):  
Postoperative Complications ◽  
Mitomycin C ◽  
Recurrence Rate ◽  
University Hospital ◽  
Beta Radiation ◽  
Conjunctival Autograft ◽  
Group A ◽  
Pterygium Excision ◽  
Group B ◽  
Primary Pterygium

Purpose: To compare the recurrence rate of primary pterygium surgery after the adjuvant use of Beta radiation, Mitomycin C, and conjunctival autograft. Methods: 180 eyes of 180 patients were included in the study. All cases had primary pterygium excision following the use of adjuvant therapy of Beta radiation or Mitomycin C (0.02% for 5 minutes) or conjunctival autograft. The study was conducted at Fayoum University Hospital, Fayoum, Egypt, and Misr University Hospital. The patients were randomly divided into three groups, with each group comprising 60 patients. Group (A) included patients treated with Beta radiation following Pterygium excision, group (B) patients had primary pterygium excision with the application of 0.02% Mitomycin C for 5 minutes, and group (C) patients had conjunctival autograft to cover the bare area after pterygium excision. Patients were followed up for three years postoperatively. Results: group A had the highest recurrence rate (33.3%) followed by group B (13.3%), and finally group C presented a recurrence rate of 6.7%. Group B showed the highest rate of intra-ocular postoperative complications, while no intra-ocular complications were recorded in group C. Common complications in groups A and B were scleral melting, keratitis, and Dellen formation. Conclusion: Using conjunctival autograft after primary pterygium excision gives the best results regarding the rate of recurrence and postoperative complications. Meanwhile, B-radiation or Mitomycin C did not prove to be as good.

PRIMARY PTERYGIUM EXCISION WITH AUTOGRAFT – WHY WASTE TISSUE

2021 ◽  
pp. 17-18
Author(s):  
Sowmiya Saras M ◽  
Mary Thomas
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Autologous Blood ◽  
Bulbar Conjunctiva ◽  
Tissue Graft ◽  
Large Size ◽  
Pterygium Excision ◽  
Primary Pterygium

AIM : To describe a modied technique of using conjunctival tissue graft from the pterygium itself in patients with primary pterygium and to measure the outcome. METHODS : 40 patients with primary pterygium were included in this prospective observational study from December 2018 to December 2019. Conjunctival layer was separated from the underlying pterygium and cut to get a rectangular graft. Pterygium tissue then excised completely. Cornea scraping done. Graft was placed over the bare sclera and was taken up by autologous blood. Follow up was done on POD 1, 1 week, 1st, 3rd & 6th month. RESULTS: 12 out of 40 patients (30%) had graft oedema on POD 1, 8 out of 40 patients (20%) had graft retraction. Granuloma was seen in 2 out of 40 patients (5%). None had recurrence. Cosmetic acceptance was good in all cases. CONCLUSION: This method is useful to prevent recurrence, in circumstances to cover the large size defect and in glaucoma patients to preserve the superior bulbar conjunctiva for future glaucoma surgeries if needed.

Long-Term Density Changes in Corneal Layers After Primary Pterygium Excision With Topical Mitomycin-C

Cornea ◽  
2016 ◽  
Vol 35 (8) ◽  
pp. 1093-1096 ◽  
Author(s):  
Ka Wai Kam ◽  
Rachel P. W. Kwok ◽  
Michael W. Belin ◽  
Alvin L. Young
Keyword(s):  
Mitomycin C ◽  
Pterygium Excision ◽  
Primary Pterygium

scholarly journals Diamond burr superficial keratectomy with mitomycin C for corneal scarring and high corneal astigmatism after pterygium excision

2013 ◽  
pp. 951 ◽  
Author(s):  
Engin Bilge Ozgurhan ◽  
Necip Kara ◽  
Aydin Yildirim ◽  
Ercüment Bozkurt ◽  
Demirok ◽  
...  
Keyword(s):  
Mitomycin C ◽  
Corneal Astigmatism ◽  
Corneal Scarring ◽  
Diamond Burr ◽  
Pterygium Excision

Surgical Outcome of Primary Pterygium Excision with Conjunctival Autograft

2015 ◽  
Vol 56 (6) ◽  
pp. 856 ◽  
Author(s):  
Dong Ik Kim ◽  
Mee Kum Kim ◽  
Won Ryang Wee ◽  
Joo Youn Oh
Keyword(s):  
Surgical Outcome ◽  
Conjunctival Autograft ◽  
Pterygium Excision ◽  
Primary Pterygium

scholarly journals Preoperative subconjunctival combined injection of bevacizumab and mitomycin C before the surgical excision of primary pterygium: clinical and histological results

2017 ◽  
Vol Volume 11 ◽  
pp. 493-501 ◽  
Author(s):  
Alahmady Hamad Alsmman ◽  
Gamal Abd Ellateif Radwan ◽  
Mortada Ahmed Abozaid ◽  
Usama Ali Mohammed ◽  
Nesreen Gamal Eldein Abd Elhaliem
Keyword(s):  
Mitomycin C ◽  
Surgical Excision ◽  
Histological Results ◽  
Primary Pterygium

scholarly journals Histamine-1 Receptors Expression in Primary Pterygium Tissue is Higher than Normal Conjunctival Tissue

2019 ◽  
Vol 12 (3) ◽  
pp. 1441-1448
Author(s):  
Putu Yuliawati ◽  
Cynthia Dewi M ◽  
A A A Sukartini Djelantik ◽  
Putu Budhiastra ◽  
N K Niti Susila
Keyword(s):  
Cell Proliferation ◽  
Observational Study ◽  
Case Control Study ◽  
Case Control ◽  
Eye Disease ◽  
Nuclear Factor ◽  
Study Approach ◽  
Final Score ◽  
Control Study ◽  
Primary Pterygium

Pterygium is an eye disease with multifactorial etiopathogenesis. Molecular factors such as cell proliferation and inflammatory mediators are associated with increased calcium mobilization and activation of nuclear factor kβ mediated by histamine-1 receptors (H1R). This study aims to determine whether the expression of H1R primary pterygium tissue is higher than normal conjunctival tissue and the expression of H1R based on pterygium grades. This study was an analytic observational study with a case-control study approach at Sanglah General Hospital, Bali Mandara Eye Hospital, and Mangusada Hospital. The study was conducted from November 2017 to April 2018. The pterygium and conjunctival tissues obtained from 28 subjects in the same eye and examined for H1R expression by immunohistochemistry. The results of this study obtained 64.3% of women with a mean age of 54.2 ± 7.8 years. There was no difference in mean H1R expression between pterygium grades in the final score (P = 0.759). There was a mean difference of H1R between primary pterygium (42.50) and normal conjunctival tissue (14.50) with P <0.001. Only tissue types affected the expression of H1R in the final score (B = 4.893; 95% CI 4.363-5.423; P <0.001). It was concluded that the expression of H1R primary pterygium tissue was higher in primary pterygium than normal conjunctival tissue.

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