Chlorhexidine and other alternatives for povidone-iodine in ophthalmic surgery

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Piotr Kanclerz ◽  
William G. Myers
1995 ◽  
Vol 119 (6) ◽  
pp. 701-705 ◽  
Author(s):  
LEONARD APT ◽  
SHERWIN J. ISENBERG ◽  
ROBERT YOSHIMORI ◽  
ALVIN CHANG ◽  
GEOFFREY C. LAM ◽  
...  

1997 ◽  
Vol 124 (1) ◽  
pp. 31-35 ◽  
Author(s):  
SHERWIN J. ISENBERG ◽  
LEONARD APT ◽  
ROBERT YOSHIMORI ◽  
CATHERINE PHAM ◽  
NAM K. LAM

2018 ◽  
Vol 29 (6) ◽  
pp. 673-677 ◽  
Author(s):  
Rosario Musumeci ◽  
Francesco Bandello ◽  
Marianna Martinelli ◽  
Enrico Calaresu ◽  
Clementina Elvezia Cocuzza

Purpose:To evaluate the bactericidal activity of a diluted povidone-iodine formulation (0.6%) in comparison with the most used 5% povidone-iodine solution ophthalmic preparation.Methods:In vitro bactericidal activity comparison between 0.6% povidone-iodine versus 5% povidone-iodine formulations, against these bacteria: Staphylococcus aureus ATCC 25923, Staphylococcus aureus ATCC 43300, Staphylococcus epidermidis ATCC 12228, linezolid-resistant Staphylococcus epidermidis α99 strain, a clinical isolate, Pseudomonas aeruginosa ATCC 27853, Escherichia coli ATCC 25922.Results:About 0.6% povidone-iodine formulation was demonstrated to be faster than 5% povidone-iodine preparation in killing Gram-positive as well as Gram-negative bacteria. Against a linezolid-resistant methicillin-resistant Staphylococcus epidermidis strain, 0.6% povidone-iodine formulation showed the best antiseptic efficacy requirement of 3-log10reduction in bacterial load, if compared with the 5% povidone-iodine formulation.Conclusion:Our investigation has demonstrated that the more diluted 0.6% preparation was more rapidly bactericidal than the 5% povidone-iodine formulation, most probably due to the fact that dilution from 5% to 0.6% increases the amount of free iodine. While our finding must be confirmed by in vivo clinical studies, this fact constitutes an intriguing news for what concerns the use of povidone-iodine eye drops in the ocular surface treatment before intravitreal injections as well as ophthalmic surgery.


Anaesthesia ◽  
2006 ◽  
Vol 61 (11) ◽  
pp. 1128-1129 ◽  
Author(s):  
Y. K. Ghosh ◽  
H. Ahluwalia ◽  
J. Beamer

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Andrzej Grzybowski ◽  
Hiroyuki Shimada ◽  
Hiroyuki Nakashizuka ◽  
Jagger Koerner

2004 ◽  
Vol 21 (2) ◽  
pp. 101-106
Author(s):  
D. Henzler ◽  
R. Kramer ◽  
U. H. Steinhorst ◽  
S. Piepenbrock ◽  
R. Rossaint ◽  
...  

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