Low-concentration povidone-iodine for the prevention of intraocular infections in ophthalmic surgery

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Andrzej Grzybowski ◽  
Hiroyuki Shimada ◽  
Hiroyuki Nakashizuka ◽  
Jagger Koerner
Keyword(s):  
Povidone Iodine ◽  
Ophthalmic Surgery ◽  
Low Concentration

The Effect of Povidone-Iodine Solution Applied at the Conclusion of Ophthalmic Surgery

1995 ◽  
Vol 119 (6) ◽  
pp. 701-705 ◽  
Author(s):  
LEONARD APT ◽  
SHERWIN J. ISENBERG ◽  
ROBERT YOSHIMORI ◽  
ALVIN CHANG ◽  
GEOFFREY C. LAM ◽  
...  
Keyword(s):  
Povidone Iodine ◽  
Iodine Solution ◽  
Ophthalmic Surgery ◽  
Povidone Iodine Solution

scholarly journals Antiseptic effect of low-concentration povidone-iodine applied with a depot device in the conjunctiva before cataract surgery

Eye ◽  
2018 ◽  
Vol 32 (12) ◽  
pp. 1900-1907
Author(s):  
Simon Wass ◽  
Grethe Albrektsen ◽  
Maria Tjåland Ødegård ◽  
Mari Sand ◽  
Dordi Austeng
Keyword(s):  
Cataract Surgery ◽  
Povidone Iodine ◽  
Low Concentration

Enhanced wound healing by topical application of ointment containing a low concentration of povidone-iodine

2016 ◽  
Vol 25 (9) ◽  
pp. 521-529 ◽  
Author(s):  
O. Mitani ◽  
A. Nishikawa ◽  
I. Kurokawa ◽  
E.C. Gabazza ◽  
M. Ikeda ◽  
...  
Keyword(s):  
Wound Healing ◽  
Topical Application ◽  
Povidone Iodine ◽  
Low Concentration

Efficacy of Topical Povidone-Iodine During the First Week After Ophthalmic Surgery

1997 ◽  
Vol 124 (1) ◽  
pp. 31-35 ◽  
Author(s):  
SHERWIN J. ISENBERG ◽  
LEONARD APT ◽  
ROBERT YOSHIMORI ◽  
CATHERINE PHAM ◽  
NAM K. LAM
Keyword(s):  
Povidone Iodine ◽  
Ophthalmic Surgery

In vitro bactericidal activity of 0.6% povidone-iodine eye drops formulation

2018 ◽  
Vol 29 (6) ◽  
pp. 673-677 ◽  
Author(s):  
Rosario Musumeci ◽  
Francesco Bandello ◽  
Marianna Martinelli ◽  
Enrico Calaresu ◽  
Clementina Elvezia Cocuzza
Keyword(s):  
Staphylococcus Aureus ◽  
Bactericidal Activity ◽  
Staphylococcus Epidermidis ◽  
Povidone Iodine ◽  
Bacterial Load ◽  
Eye Drops ◽  
Ophthalmic Surgery ◽  
Free Iodine

Purpose:To evaluate the bactericidal activity of a diluted povidone-iodine formulation (0.6%) in comparison with the most used 5% povidone-iodine solution ophthalmic preparation.Methods:In vitro bactericidal activity comparison between 0.6% povidone-iodine versus 5% povidone-iodine formulations, against these bacteria: Staphylococcus aureus ATCC 25923, Staphylococcus aureus ATCC 43300, Staphylococcus epidermidis ATCC 12228, linezolid-resistant Staphylococcus epidermidis α99 strain, a clinical isolate, Pseudomonas aeruginosa ATCC 27853, Escherichia coli ATCC 25922.Results:About 0.6% povidone-iodine formulation was demonstrated to be faster than 5% povidone-iodine preparation in killing Gram-positive as well as Gram-negative bacteria. Against a linezolid-resistant methicillin-resistant Staphylococcus epidermidis strain, 0.6% povidone-iodine formulation showed the best antiseptic efficacy requirement of 3-log10reduction in bacterial load, if compared with the 5% povidone-iodine formulation.Conclusion:Our investigation has demonstrated that the more diluted 0.6% preparation was more rapidly bactericidal than the 5% povidone-iodine formulation, most probably due to the fact that dilution from 5% to 0.6% increases the amount of free iodine. While our finding must be confirmed by in vivo clinical studies, this fact constitutes an intriguing news for what concerns the use of povidone-iodine eye drops in the ocular surface treatment before intravitreal injections as well as ophthalmic surgery.

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