The article presents the results of a study of Doppler ultrasound (USDG) of arteries and veins of the upper and lower extremities of 68 children with connective tissue dysplasia of heart. When examining the veins, functional tests were carried out: Valsalva’s test and a test with compression by a sensor. In children with connective tissue dysplasia of heart and concomitant arterial hypertension, the failure of the valves of saphenous veins is more common. Also, the following pathologies are revealed: chronic venous insufficiency, angiodysplasia, congenital hypoplasia and aplasia of the deep veins of the lower extremities. Examination of the arteries revealed a spasm of the arteries of the upper and lower extremities with a constant thickness of intima-media, Raynaud’s syndrome. In such patients, the linear blood flow velocity decreases, mainly in the deep arteries of the upper and lower extremities. Doppler ultrasound should be used for early detection of changes in the arteries and veins of the upper and lower extremities in order to prevent and treat vascular diseases.