Specific Detection of Prostate Cancer Cells in Urine by RNA In Situ Hybridization

2021 ◽  
Author(s):  
Jillian N. Eskra ◽  
Daniel Rabizadeh ◽  
Jiayi Zhang ◽  
William B. Isaacs ◽  
Jun Luo ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
In Situ Hybridization ◽  
Cancer Cells ◽  
Prostate Cancer Cells ◽  
Specific Detection ◽  
Rna In Situ Hybridization

A novel method for detection of exfoliated prostate cancer cells in urine by RNA in situ hybridization

2020 ◽  
Author(s):  
Jillian N. Eskra ◽  
Daniel Rabizadeh ◽  
Leslie Mangold ◽  
Elizabeth Fabian ◽  
W. Nathaniel Brennen ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
In Situ Hybridization ◽  
Cancer Cells ◽  
Prostate Cancer Cells ◽  
Rna In Situ Hybridization ◽  
Novel Method

In situ hybridization with a chromosome 1 specific DNA probe on interphase nuclei from prostate cancer cells.

1991 ◽  
Vol 52 (2) ◽  
pp. 246 ◽  
Author(s):  
Josée J. König ◽  
Sandra de Jong ◽  
Anne Hagemeijer ◽  
Hans Romijn ◽  
Fritz H. Schröder
Keyword(s):  
Prostate Cancer ◽  
In Situ Hybridization ◽  
Cancer Cells ◽  
Dna Probe ◽  
Chromosome 1 ◽  
Prostate Cancer Cells ◽  
Interphase Nuclei

scholarly journals Analytic Validation of RNA In Situ Hybridization (RISH) for AR and AR-V7 Expression in Human Prostate Cancer

2016 ◽  
Vol 22 (18) ◽  
pp. 4651-4663 ◽  
Author(s):  
Liana B. Guedes ◽  
Carlos L. Morais ◽  
Fawaz Almutairi ◽  
Michael C. Haffner ◽  
Qizhi Zheng ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
In Situ Hybridization ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Rna In Situ Hybridization

scholarly journals A high-resolution 3D epigenomic map reveals insights into the creation of the prostate cancer transcriptome

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Suhn Kyong Rhie ◽  
Andrew A. Perez ◽  
Fides D. Lay ◽  
Shannon Schreiner ◽  
Jiani Shi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
High Resolution ◽  
Cancer Cells ◽  
Chromatin Structure ◽  
Cancer Biology ◽  
Ctcf Binding ◽  
Chromatin Interaction ◽  
Prostate Cancer Cells ◽  
Cancer Transcriptome

Abstract To better understand the impact of chromatin structure on regulation of the prostate cancer transcriptome, we develop high-resolution chromatin interaction maps in normal and prostate cancer cells using in situ Hi-C. By combining the in situ Hi-C data with active and repressive histone marks, CTCF binding sites, nucleosome-depleted regions, and transcriptome profiling, we identify topologically associating domains (TADs) that change in size and epigenetic states between normal and prostate cancer cells. Moreover, we identify normal and prostate cancer-specific enhancer-promoter loops and involved transcription factors. For example, we show that FOXA1 is enriched in prostate cancer-specific enhancer-promoter loop anchors. We also find that the chromatin structure surrounding the androgen receptor (AR) locus is altered in the prostate cancer cells with many cancer-specific enhancer-promoter loops. This creation of 3D epigenomic maps enables a better understanding of prostate cancer biology and mechanisms of gene regulation.

In Situ Thermal Denaturation of Proteins in Dunning AT-1 Prostate Cancer Cells: Implication for Hyperthermic Cell Injury

2004 ◽  
Vol 32 (10) ◽  
pp. 1384-1398 ◽  
Author(s):  
Xiaoming He ◽  
Willem F. Wolkers ◽  
John H. Crowe ◽  
David J. Swanlund ◽  
John C. Bischof
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Thermal Denaturation ◽  
Cell Injury ◽  
Prostate Cancer Cells ◽  
Denaturation Of Proteins
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