scholarly journals MP03-16 LONG-TERM FOLLOW-UP SUGGESTS HIGH SATISFACTION RATES FOR BULBOMEMBRANOUS RADIATION INDUCED URETHRAL STRICTURES TREATED WITH ANASTOMOTIC URETHROPLASTY

2021 ◽  
Vol 206 (Supplement 3) ◽  
Author(s):  
John Barnard ◽  
Aron Liaw ◽  
Joel Gelman
2018 ◽  
Vol 3 (5) ◽  
pp. 217-224 ◽  
Author(s):  
Luigi Zagra ◽  
Enrico Gallazzi

Total hip arthroplasty (THA) is widely considered one of the most successful surgical procedures in orthopaedics. It is associated with high satisfaction rates and significant improvements in quality of life following surgery. On the other hand, the main cause of late revision is osteolysis and wear, often a result of failure of bearing surfaces. Currently, several options are available to the surgeon when choosing the bearing surface in THA (ceramic-on-ceramic (CoC), ceramic-on-polyethylene (CoPE), metal-on-polyethylene (MoPE)), each with advantages and drawbacks. Very few studies have directly compared the various combinations of bearings at long-term follow-up. Randomized controlled trials show similar short- to mid-term survivorship among the best performing bearing surfaces (CoC, CoXLPE and MoXLPE). Selection of the bearing surface is often ‘experience-based’ rather than ‘evidence-based’. The aim of this paper is therefore to evaluate the main advantages and drawbacks of various types of tribology in THA, while providing practical suggestions for the surgeon on the most suitable bearing surface option for each patient.Cite this article: EFORT Open Rev 2018;3 DOI: 10.1302/2058-5241.3.180300.


ESC CardioMed ◽  
2018 ◽  
pp. 1153-1156
Author(s):  
Ersilia M. DeFilippis ◽  
Anju Nohria

Radiation-induced heart disease is a major cause of morbidity and mortality among cancer survivors. It encompasses many clinical entities, including pericardial disease, coronary artery disease, valvular disease, cardiomyopathy, conduction system abnormalities, autonomic dysfunction, and peripheral vascular disease. As the cardiovascular effects of radiation manifest many years after treatment, long-term follow-up with regular screening is essential. This chapter reviews the epidemiology and pathogenesis of radiation-induced heart disease as well as existing consensus recommendations regarding surveillance and management.


1994 ◽  
Vol 61 (1_suppl) ◽  
pp. 256-259
Author(s):  
G. Sevin ◽  
H. Gezeroglu ◽  
R. Pacchiele ◽  
A. Carbone

Sigma-rectum pouch (Mainz Pouch II) operation, which is a detubularized modification of the well-known ureterosigmoidostomy is becoming a popular alternative of urinary diversion in selected patients. 12 male patients underwent this operation due to locally invasive bladder tumours or incurable urethral strictures and fistulas. The pouch was tailored using 12 cm of sigmoid colon and rectum and performing a side to side anastomosis of the detubularized bowel in an inverted U shape. The new formed pouch was fixed onto the posterior peritoneum so that traction affecting the pouch was minimized. Postoperative radiological analysis revealed no obstruction or ureteral reflux. Urodynamic studies revealed low pressure, high volume reservoirs. Only 1 patient had reservoir wall contractions of low amplitude during filling. Although early postoperative blood chemistry did not reveal any metabolic abnormality, at long-term follow-up some patients showed important electrolyte and acid-base disorders.


Surgery ◽  
2007 ◽  
Vol 142 (6) ◽  
pp. 819-822.e1 ◽  
Author(s):  
Giuseppe Ippolito ◽  
F. Fausto Palazzo ◽  
Frederic Sebag ◽  
Jean François Henry

2001 ◽  
Vol 35 (7-8) ◽  
pp. 806-810 ◽  
Author(s):  
Diclehan Kilic ◽  
Seren Ozenirler ◽  
Ibrahim Egehan ◽  
Ayse Dursun

BACKGROUND: Radiation-induced gastrointestinal toxicity is a significant concern for patients who are treated with this modality for pelvic malignancies. Eicosanoids and free radicals are thought to be among the reasons for this effect. Sulfasalazine is an inhibitor of their synthesis in the mucosa. OBJECTIVE: To determine whether sulfasalazine can reduce the radiation-induced acute gastrointestinal complications. METHODS: In this prospective, double-blind study, 31 patients receiving pelvic radiotherapy were randomized to receive two sulfasalazine 500-mg tablets twice daily or placebo, administered orally from the first day of irradiation. Patients were evaluated weekly, and gastrointestinal toxicities were graded according to the Late Effect of Normal Tissue — Subjective Objective Management Analytic (LENT-SOMA) toxicity table during pelvic radiotherapy. On the last day of week 5, the subjects were graded endoscopically, and biopsies taken from the rectum were classified histopathologically. RESULTS: Groups did not differ in age, gender, tumor site, or irradiation procedure. During radiotherapy, grade 2 or higher gastrointestinal toxicity occurred in 20% (3/15) and 63% (10/16) of the sulfasalazine and placebo groups, respectively. This difference was significant (p = 0.017). No statistically significant differences were found in endoscopic and histopathologic evaluations. CONCLUSIONS: Sulfasalazine is effective in decreasing clinically acute gastrointestinal toxicities. Long-term follow-up with the subjects will help to determine the net effect of sulfasalazine on the radiation-induced gastrointestinal injuries.


1997 ◽  
Vol 83 (3) ◽  
pp. 721-723 ◽  
Author(s):  
Moshe E. Stein ◽  
Michelle Leviov ◽  
Keren Drumea ◽  
Ludmilla Goralnik ◽  
Innes Miselevich ◽  
...  

We report a case of radiation-induced retroperitoneal leiomyosarcoma which developed 37 years after the patient received radiation therapy for testicular seminoma. The sarcoma originated within the para-aortic field, extensively involving neighboring organs, soft tissue and muscle tissues, and could be only partially resected. The absolute number of these secondary sarcomas is low, but the risk of developing such neoplasms calls for awareness in the long-term follow-up of cured seminoma patients.


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