Three-dimensional intracranial EEG monitoring in presurgical assessment of MRI-negative frontal lobe epilepsy

This chapter is concerned with the use of subdural EEG for location of the epileptogenic zone and for functional mapping in frontal lobe epilepsy (FLE), tasks that are both necessary before epilepsy surgery in various subtypes of FLE. It reviews clinical features of subtypes of FLE, individualized electrode arrays, and the recording and analysis of epileptiform abnormalities of ictal and interictal states. It then reviews the principles of functional mapping by cortical stimulation and by other methods, e.g. intrinsic EEG activity. Intrinsic EEG activity consists of Bereitschaftspotentials or readiness potentials, judgment-related potentials from pre-supplementary motor area (SMA), somatosensory evoked potentials from SMA proper and pre-SMA, and language-related potentials. It also reviews new methods such as event-related synchronization, event-related desynchronization, coherence analysis for functional mapping, wide-band EEG analysis of slow (DC) shifts and high-frequency oscillations, and three-dimensional EEG source analysis for epileptogenic mapping.

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Frontal Lobe Epilepsy with Supplementary Motor Seizures Successfully Treated with Cortical Resection following Intracranial EEG/CCTV Monitoring and Functional Mapping

Psychiatry and Clinical Neurosciences ◽

10.1111/j.1440-1819.1993.tb02068.x ◽

1993 ◽

Vol 47 (2) ◽

pp. 267-270

Author(s):

Takayasu Tottori ◽

Kazuichi Yagi ◽

Tadahiro Mihara ◽

Kazumi Matsuda ◽

Koichi Baba ◽

...

Keyword(s):

Frontal Lobe ◽

Functional Mapping ◽

Frontal Lobe Epilepsy ◽

Intracranial Eeg

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Preoperative Electroencephalographic Investigation in Frontal Lobe Epilepsy: Electroencephalographic and Electrocorticographic Recordings

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques ◽

10.1017/s0317167100032698 ◽

1991 ◽

Vol 18 (S4) ◽

pp. 559-563 ◽

Cited By ~ 27

Author(s):

L.F. Quesney

Keyword(s):

Frontal Lobe ◽

Frontal Lobe Epilepsy ◽

Eeg Monitoring ◽

Seizure Onset ◽

Epileptic Patients ◽

Intracranial Electrodes

ABSTRACT:The first section of this article deals with specific anatomic and pathophysiologic factors which contribute to a poor EEG localization of the interictal epileptic abnormality and to the unreliable seizure onset localization commonly reported in patients with frontal lobe epilepsy. The localizing effectiveness of long term EEG monitoring was reviewed in four different groups of frontal lobe epileptic patients who underwent preoperative EEG investigation with extracranial and intracranial electrodes. The results of this study reveal a continuum distribution of interictal epileptic disturbances, ranging from focal abnormalities to lobar or multi-lobar epileptogenesis. A frontal lobe localization of the seizure generator based on ictal recordings obtained with extracranial electrodes is rather poor and much more reliable results can be obtained by depth-electroencephalography.

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Ictal SPECT analyzed by three-dimensional stereotactic surface projection in frontal lobe epilepsy patients

Epilepsy Research ◽

10.1016/j.eplepsyres.2005.09.032 ◽

2006 ◽

Vol 68 (2) ◽

pp. 95-102 ◽

Cited By ~ 11

Author(s):

Masafumi Fukuda ◽

Hiroshi Masuda ◽

Jyunpei Honma ◽

Shigeki Kameyama ◽

Ryuichi Tanaka

Keyword(s):

Frontal Lobe ◽

Three Dimensional ◽

Frontal Lobe Epilepsy ◽

Ictal Spect ◽

Surface Projection

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Prognostic factors in presurgical assessment of frontal lobe epilepsy

Journal of Neurology Neurosurgery & Psychiatry ◽

10.1136/jnnp.66.3.350 ◽

1999 ◽

Vol 66 (3) ◽

pp. 350-356 ◽

Cited By ~ 72

Author(s):

C H Ferrier ◽

J Engelsman ◽

G Alarcon ◽

C D Binnie ◽

C E Polkey

Keyword(s):

Prognostic Factors ◽

Frontal Lobe ◽

Frontal Lobe Epilepsy ◽

Presurgical Assessment

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Use of statistical parametric mapping of 18F-FDG-PET in frontal lobe epilepsy

Nuklearmedizin ◽

10.1055/s-0038-1625189 ◽

2003 ◽

Vol 42 (05) ◽

pp. 190-196 ◽

Cited By ~ 10

Author(s):

H. Amthauer ◽

M. Merschhemke ◽

L. Lüdemann ◽

E. Hartkop ◽

J. Ruf ◽

...

Keyword(s):

Frontal Lobe ◽

Fdg Pet ◽

Statistical Parametric Mapping ◽

Clinical Findings ◽

Control Group ◽

Frontal Lobe Epilepsy ◽

Eeg Monitoring ◽

Monitoring Method ◽

Eeg Recordings ◽

Surface Eeg

Summary: Aim: Evaluation of the use of statistical parametrical mapping (SPM) of FDG-PET for seizure lateralization in frontal lobe epilepsy. Patients: 38 patients with suspected frontal lobe epilepsy supported by clinical findings and video-EEG monitoring. Method: Statistical parametrical maps were generated by subtraction of individual scans from a control group, formed by 16 patients with negative neurological/psychiatric history and no abnormalities in the MR scan. The scans were also analyzed visually as well as semiquantitatively by manually drawn ROIs. Results: SPM showed a better accordance to the results of surface EEG monitoring compared with visual scan analysis and ROI quantification. In comparison with intracranial EEG recordings, the best performance was achieved by combining the ROI based quantification with SPM analysis. Conclusion: These findings suggest that SPM analysis of FDG-PET data could be a useful as complementary tool in the evaluation of seizure focus lateralization in patients with supposed frontal lobe epilepsy.

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