Correlation of ultrasound features and the Risk of Ovarian Malignancy Algorithm score for different histopathological subtypes of benign adnexal masses

Mature cystic teratoma often referred to as dermoid cysts have been diagnosed using all imaging modalities. Dermoid cysts present various and complex ultrasonographic aspects. At times diagnosis may be difficult and lead to confusion due to its complex solid and cystic nature. The specificity for diagnosis of fat and calcification makes computed tomography (CT) scan the modality of choice. But CT scan is high technique equipment, expensive and may not be affordable or available at all places. Advances in the quality of USG machines, better experiences of ultrasound operators and thorough analysis of all ultrasound features that characterise dermoid cysts have resulted in an increased accuracy of exact ultrasonographic diagnosis of dermoid cysts in the vast majority of the cases and now used as the first preoperative work-up method of choice for the assessment of adnexal masses in clinical practices. DOI: http://dx.doi.org/10.3126/jkmc.v3i1.10920Journal of Kathmandu Medical CollegeVol. 3, No. 1, Issue 7, Jan.-Mar., 2014, Page: 26-31

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Artificial neural network computer prediction of ovarian malignancy in women with adnexal masses

International Journal of Gynecology & Obstetrics ◽

10.1016/j.ijgo.2005.01.034 ◽

2005 ◽

Vol 89 (2) ◽

pp. 108-113 ◽

Cited By ~ 11

Author(s):

D. Szpurek ◽

R. Moszynski ◽

A. Smolen ◽

S. Sajdak

Keyword(s):

Neural Network ◽

Artificial Neural Network ◽

Ovarian Malignancy ◽

Computer Prediction ◽

Adnexal Masses ◽

Network Computer ◽

Artificial Neural

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Ethnic disparity in clinical performance between multivariate index assay and CA125 in detection of ovarian malignancy

Future Oncology ◽

10.2217/fon-2019-0310 ◽

2019 ◽

Vol 15 (26) ◽

pp. 3047-3051 ◽

Cited By ~ 1

Author(s):

Charles Dunton ◽

Rowan G Bullock ◽

Herbert Fritsche

Keyword(s):

Ovarian Cancer ◽

Cancer Detection ◽

Clinical Performance ◽

Lower Sensitivity ◽

Ovarian Malignancy ◽

Cutoff Value ◽

Adnexal Masses ◽

Is Implementation ◽

Prospective Trials ◽

Caucasian Women

Aim: Based on evidence that African–American (AA) women have lower CA125 values than Caucasian (C) women, we investigated this to see if this disparity would have an impact on ovarian cancer detection using CA125 and multivariate index assay (MIA). Materials & methods: Serum from two prospective trials of 1029 (274 malignancies [250 C/24AA]) were analyzed for CA125 and MIA results. Clinical performance was calculated. Results: Sensitivity of MIA in Caucasian women was 93.2%, 74.4% for CA125 at the ACOG approved cut-off level of 200 U/ml cutoff, and 80.4% using the 2007, Dearking 67 U/ml cutoff. In AA American women, MIA sensitivity was 79.2%, 33.3% for CA125 at the ACOG approved cut-off levels and 62.5% at the 2007, Dearking 67 U/ml cutoff. Conclusion: Our results support that CA125 in AA women with adnexal masses has lower sensitivity than MIA no matter what the cutoff value is. Implementation of MIA in evaluation of adnexal masses should increase sensitivity of detection of malignancy compared with CA125, particularly in AA women.

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The role of “penumbra sign” and diffusion-weighted imaging in adnexal masses: do they provide a clue in differentiating tubo-ovarian abscess from ovarian malignancy?

Polish Journal of Radiology ◽

10.5114/pjr.2021.111986 ◽

2021 ◽

Vol 86 (1) ◽

pp. 661-671

Author(s):

Ranjan Patel ◽

Anju Garg ◽

Rashmi Dixit ◽

Gauri Gandhi ◽

Nita Khurana

Keyword(s):

Diffusion Weighted Imaging ◽

Ovarian Malignancy ◽

Adnexal Masses ◽

Diffusion Weighted ◽

And Diffusion ◽

Ovarian Abscess

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Clinicopathological profile of adnexal masses presenting to a tertiary-care hospital in Bhutan

South Asian Journal of Cancer ◽

10.4103/sajc.sajc_303_18 ◽

2019 ◽

Vol 08 (03) ◽

pp. 168-172

Author(s):

Rojna Rai ◽

Pema Choden Bhutia ◽

Ugyen Tshomo

Keyword(s):

Statistical Analysis ◽

Postmenopausal Women ◽

Adnexal Mass ◽

Tertiary Care Hospital ◽

Preoperative Evaluation ◽

Tertiary Care ◽

Care Hospital ◽

Ovarian Malignancy ◽

Adnexal Masses ◽

Common Malignancy

Abstract Context: Adnexal masses of ovarian origin are of growing concern due to high fatality associated with ovarian malignancy because they are diagnosed at advanced stage due to vague symptoms and absence of recommended screening tests. Aims: The aim was to study the prevalence of histopathologic types of adnexal masses in different age groups and to analyze the accuracy of preoperative evaluation in diagnosing ovarian malignancy. Settings and Design: This was a cross-sectional study carried out in the Department of Obstetrics and Gynecology of a tertiary care hospital in Bhutan with gynecologic-oncology services, from January to December 2017. Subjects and Methods: Women presenting with adnexal mass were evaluated and those meeting criteria were enrolled. They were evaluated preoperatively with complete history, examination, ultrasound, and tumor markers. Risk of malignancy index (RMI) was calculated for all patients. Following surgery, histopathology results were compared with preoperative evaluation. Statistical Analysis Used: Chi-square test, t-test, Cohen's Kappa, and receiver operating characteristic curve analysis were used for statistical analysis. Results: Of 165 patients evaluated, 127 fulfilling criteria were enrolled. Adnexal masses of ovarian origin were most common (n = 102, 80.3%), of which 12.7% were malignant. Epithelial ovarian malignancy was the most common malignant ovarian tumor, serous cystadenocarcinoma being the most common. Malignancy was significantly more in older, postmenopausal women with high RMI. Seven out of 11 women with high RMI were diagnosed in Stage 3 or 4. RMI score at cutoff of 200 was 54.6% sensitive and 85.7% specific. Conclusions: Adnexal mass of ovarian origin was the most common. Malignancy was significantly more in older, postmenopausal women with high RMI. RMI showed moderate correlation in diagnosing epithelial ovarian malignancies.

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