scholarly journals Association of angiotensin-converting enzyme 2 gene polymorphism and enzymatic activity with essential hypertension in different gender

Medicine ◽  
2018 ◽  
Vol 97 (42) ◽  
pp. e12917 ◽  
Author(s):  
Qi Zhang ◽  
Mingyu Cong ◽  
Ningning Wang ◽  
Xueyan Li ◽  
Hao Zhang ◽  
...  
2004 ◽  
Vol 22 (Suppl. 2) ◽  
pp. S317-S318
Author(s):  
J. Zhong ◽  
Z. Zhu ◽  
T. Cao ◽  
Z. Yan ◽  
C. Shen ◽  
...  

2006 ◽  
Vol 34 (3) ◽  
pp. 272-283 ◽  
Author(s):  
L Yi ◽  
YH Gu ◽  
XL Wang ◽  
LZ An ◽  
XD Xie ◽  
...  

To assess the significance of polymorphisms of the genes for angiotensin-converting enzyme ( ACE), angiotensin-converting enzyme 2 ( ACE2) and urotensin II (UTS2) as risk factors for essential hypertension in two populations from north-western China, we enrolled 198 patients with essential hypertension and 131 healthy controls from the Han population and 120 patients with essential hypertension and 102 healthy controls from the Dongxiang population. Polymerase chain reaction (PCR) and PCR-restriction fragment length polymorphism were used to analyse gene polymorphisms. The results provided evidence that genetic variants of UTS2 and ACE2 may play a role in the development of essential hypertension in these populations. Polymorphisms of ACE were not associated with essential hypertension in either population. This is the first report showing that the S89N single-nucleotide polymorphism of the UTS2 gene is associated with essential hypertension.


2012 ◽  
Vol 16 (3) ◽  
pp. 174-177 ◽  
Author(s):  
Kamna Srivastava ◽  
Ruchi Sundriyal ◽  
Prakash C. Meena ◽  
Jagriti Bhatia ◽  
Rajiv Narang ◽  
...  

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