Extramedullary plasmacytoma of the kidney in an HIV-positive patient

The aim of this paper is to describe a case report of EMP in an HIV-positive patient. A 44-year-old, dark-skinned HIV-infected woman was referred to the Oral Diseases Treatment Center with a swelling at palate and left gingival fornix in the maxilla. Biopsy was taken and the oral lesion was diagnosed as EMP with well-differentiated plasma cells and restriction of the lambda light-chain. Skeletal survey was performed and no radiograph alterations were observed, thus supporting the diagnosis of EMP. Patient was referred to treatment and after two months of chemo and radiotherapy, an expanding lesion was observed in L5/S1 patient’s vertebrae. Biopsy of the spinal lesion was consistent with lymphoma with plasmocitary differentiation, supporting the diagnosis of multiple myeloma (MM). Regarding the medical history, the final diagnostic was an oral extramedullary plasmacytoma with rapid progression into multiple myeloma. It is crucial to emphasize the relevance of HIV infection as a risk factor for both aggressive clinical behavior and unusual clinical presentation of extramedullary plasmacytoma cases.

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Extramedullary plasmacytoma of the ureter in an HIV-positive patient

International Cancer Conference Journal ◽

10.1007/s13691-017-0300-3 ◽

2017 ◽

Vol 6 (4) ◽

pp. 171-174

Author(s):

Takashi Nagai ◽

Takehiko Okamura ◽

Yosuke Taki ◽

Yutaro Tanaka ◽

Daichi Kobayashi ◽

...

Keyword(s):

Extramedullary Plasmacytoma ◽

Positive Patient ◽

Hiv Positive

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Oral extramedullary plasmacytoma in a HIV positive patient

Oral Oncology ◽

10.1016/j.oraloncology.2016.11.007 ◽

2017 ◽

Vol 64 ◽

pp. e4-e5

Author(s):

Premalatha Shetty ◽

Flora D. Lobo ◽

R. Arvind ◽

Sameep S. Shetty

Keyword(s):

Extramedullary Plasmacytoma ◽

Positive Patient ◽

Hiv Positive

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A Giant Solitary Adrenal Plasmacytoma in a Patient with HIV: A Rare Case Report and Review of the Literature

Case Reports in Urology ◽

10.1155/2021/6654437 ◽

2021 ◽

Vol 2021 ◽

pp. 1-6

Author(s):

Mehdi Chennoufi ◽

Ibrahim Boukhannous ◽

Mohamed Mokhtari ◽

Anouar El Moudane ◽

Mohamed Irzi ◽

...

Keyword(s):

Adrenal Gland ◽

Immunohistochemical Study ◽

Locally Advanced ◽

Extramedullary Plasmacytoma ◽

Positive Patient ◽

Hiv Positive ◽

Patient Reported ◽

Rare Case Report ◽

Rare Malignancy ◽

Solitary Extramedullary Plasmacytoma

Solitary extramedullary plasmacytoma (EMP) involving the adrenal gland is an extremely rare malignancy. We report a case of a solitary adrenal plasmacytoma in an HIV-positive 50-year-old woman on antiretroviral therapy who presented with a rapidly progressing lumbar left masse. A CT scan objectified a locally advanced left adrenal mass measuring 135mm long axis. A biopsy was taken, and the histopathology with the immunohistochemical study objectified an adrenal gland plasmacytoma. The skeletal survey and the sternal suction biopsy did not show any abnormalities. The diagnosis of a solitary EMP of the adrenal gland was made. There are only 10 cases of solitary adrenal plasmacytoma with only one case associated with an HIV-positive patient reported in the literature. Therefore, this paper is aimed at presenting the second case of an HIV-positive patient diagnosed with solitary adrenal plasmacytoma.

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