scholarly journals Lipid accumulation product as useful predictors of stroke

Medicine ◽  
2022 ◽  
Vol 101 (2) ◽  
pp. e28444
Author(s):  
Bing Zhang ◽  
Xiao Wang ◽  
Li Zhong ◽  
Yu-Shan Wang
Keyword(s):  
Lipid Accumulation ◽  
Lipid Accumulation Product

Value of lipid accumulation product for the assessment of metabolic syndrome in women with polycystic ovary syndrome

2013 ◽  
Author(s):  
Antic Ivana Bozic ◽  
Jelica Bjekic-Macut ◽  
Dimitrios Panidis ◽  
Danijela Vojnovic Milutinovic ◽  
Biljana Kastratovic ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Polycystic Ovary Syndrome ◽  
Lipid Accumulation ◽  
Polycystic Ovary ◽  
Lipid Accumulation Product ◽  
Ovary Syndrome

Lipid accumulation product and insulin resistance in Iranian PCOS prevalence study

2013 ◽  
Vol 81 (1) ◽  
pp. 52-57 ◽  
Author(s):  
Farhad Hosseinpanah ◽  
Maryam Barzin ◽  
Hadi Erfani ◽  
Sara Serahati ◽  
Fahimeh Ramezani Tehrani ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Lipid Accumulation ◽  
Prevalence Study ◽  
Lipid Accumulation Product

scholarly journals Interaction Analysis of Lipid Accumulation Product and Family History of Diabetes on Impaired Fasting Glucose and Diabetes Risk in Population with Normotension in Eastern China: A Community-based Cross-sectional Survey

2021 ◽  
Author(s):  
Li Shu ◽  
Yingying Zhao ◽  
Yanqi Shen ◽  
Xiaolu Li ◽  
Mengting Qiu ◽  
...  
Keyword(s):  
Family History ◽  
Impaired Fasting Glucose ◽  
Lipid Accumulation ◽  
Significant Interaction ◽  
Fasting Glucose ◽  
Diabetes Risk ◽  
Lipid Accumulation Product ◽  
Family History Of Diabetes ◽  
Significant Difference ◽  
History Of

Abstract Background: Lipid accumulation product (LAP) is considered to be a new convenient useful indicator to assess the visceral fat. However, the association between LAP and family history of diabetes remains an undetermined concept. Therefore, we aimed to evaluate the risk factors of impaired fasting glucose (IFG) and diabetes, and explore the possible interacting influences of LAP with other factors on the risk of IFG and diabetes among Chinese normotension adults.Methods: A multistage stratified cluster sampling method was conducted to select urban residents aged 45-86 years in Bengbu, China. For each eligible participant, data on questionnaire survey, anthropometric measurements and laboratory tests were obtained. LAP was calculated and divided into four categories according to quartile. The effects of body mass index (BMI), waist circumference (WC), waist to height ratio (WHtR) and LAP for predicting IFG and diabetes were performed by multiple logistic regressions and receiver operating characteristic (ROC) analyses. The interaction effects were evaluated by relative excess risk of interaction (RERI), attributable proportion due to interaction (AP) and synergy index (SI). If the 95% CI of RERI and AP do not include 0, the 95% CI of SI do not include 1, the interactions are statistically significant. Results: 6467 normotension subjects (2695 men and 3772 women) were enrolled in our study, the prevalence of IFG and diabetes were 9.37% and 14.33%, respectively. It was revealed that the prevalence rates of IFG and diabetes were gradually increased according to increasing LAP quartiles (P for trend <0.001). When assessed using ROC curve analysis, LAP exhibited higher diagnostic accuracy for identifying IFG and diabetes than BMI, the area under the AUC curve was 0.650 (95% CI: 0.637 to 0.662). After adjustment for age, sex, educational level and other confounding factors, multivariate logistic regression analyses indicated that subjects with the fourth quartile of LAP were more likely to develop IFG (adjusted OR: 2.735, 95% CI: 1.794-4.170) and diabetes (adjusted OR: 1.815, 95% CI: 1.297-2.541) than those with the first quartile. A significant interaction between LAP and family history of diabetes was observed in participants (RERI=1.538, 95%CI: 0.167 to 3.612; AP=0.375, 95%CI: 0.118 to 0.631; SI=1.980, 95%CI: 1.206 to 3.251), but there is no statistically significant difference between LAP and general obesity. However, a significant interaction between LAP and abdominal obesity was indicated by the value of RERI (1.492, 95%CI: 0.087 to 3.723) and AP (0.413, 95%CI: 0.014 to 0.756), but not the value of SI (1.824, 95%CI: 0.873 to 3.526). Conclusion: LAP significantly associates with IFG and diabetes risk in the study population, it has better performance than BMI, WC and WHtR. Apart from that, our results also demonstrated that there might be synergistic effect between LAP and family history of diabetes on the risk of IFG and diabetes.

scholarly journals Lipid accumulation product index in HIV-infected patients: a marker of cardiovascular risk

2018 ◽  
Vol 22 (3) ◽  
pp. 171-176 ◽  
Author(s):  
Milena Maria Moreira Guimarães ◽  
Dirceu Bartolomeu Greco ◽  
Allyson Nogueira Moreira ◽  
Nathalia Sernizon Guimarães ◽  
Cláudia Maria Vilas Freire ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Lipid Accumulation ◽  
Lipid Accumulation Product ◽  
Lipid Accumulation Product Index

Effect of Exercise Training on Spexin Level, Appetite, Lipid Accumulation Product, Visceral Adiposity Index, and Body Composition in Adults With Type 2 Diabetes

2021 ◽  
pp. 109980042110505
Author(s):  
Arash Mohammadi ◽  
Nahid Bijeh ◽  
Mahtab Moazzami ◽  
Kazem khodaei ◽  
Najmeh Rahimi
Keyword(s):  
Type 2 Diabetes ◽  
Body Composition ◽  
Lipid Accumulation ◽  
Visceral Adiposity ◽  
Visceral Adiposity Index ◽  
Model Assessment ◽  
Lipid Accumulation Product ◽  
Adiposity Index ◽  
Body Strength

Objective To compare the effects of resistance and aerobic training (RT and AT) on spexin (SPX), appetite, lipid accumulation product (LAP), visceral adiposity index (VAI), and body composition in type 2 diabetes mellitus (T2DM) patients. Materials and Methods: Thirty-six T2DM men were randomized to receive RT ( n = 12), AT ( n = 12), or to act as a non-exercise control (CON, n = 12) 3 days a week for 12 weeks. Results: SPX was increased after both RT and AT (66.2% and 46.5%, respectively). VAI, LAP, and homeostasis model assessment-insulin resistance (HOMA-IR) were reduced in both groups, while quantitative insulin sensitivity check index (Quicki) and McAuley’s indexes were increased following both interventions. However, the increases of both hunger and PFC in the RT group were greater than those of the AT. Moreover, the improvement of upper-body strength (41% vs. 10.3%) and lower-body strength (42.2% vs. 20.5%) in the RT group was greater than those of the AT. Conclusion: Our investigation shows that regardless of the modes of the regimen, a 12-week exercise intervention with RT and AT can effectively induce a significant improvement in SPX levels, appetite, LAP, VAI, and body composition in adults with T2DM.

scholarly journals The association of plant-based dietary patterns with visceral adiposity, lipid accumulation product, and triglyceride-glucose index in Iranian adults

2020 ◽  
Vol 53 ◽  
pp. 102531 ◽  
Author(s):  
Mahshid Shahavandi ◽  
Farhang Djafari ◽  
Hossein Shahinfar ◽  
Samira Davarzani ◽  
Nadia Babaei ◽  
...  
Keyword(s):  
Dietary Patterns ◽  
Lipid Accumulation ◽  
Visceral Adiposity ◽  
Lipid Accumulation Product ◽  
Triglyceride Glucose Index

scholarly journals Hypertriglyceridemic Waist Phenotype and Lipid Accumulation Product: Two Comprehensive Obese Indicators of Waist Circumference and Triglyceride to Predict Type 2 Diabetes Mellitus in Chinese Population

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Minrui Xu ◽  
Mingtao Huang ◽  
Deren Qiang ◽  
Jianxin Gu ◽  
Yong Li ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Dose Response ◽  
Lipid Accumulation ◽  
Hazard Ratio ◽  
Lipid Accumulation Product ◽  
Hypertriglyceridemic Waist ◽  
Additive Interactions

Purpose. To determine whether hypertriglyceridemic waist (HTGW) and high lipid accumulation product (LAP) preceded the incidence of type 2 diabetes mellitus (T2DM), and to investigate the interactions of HTGW and LAP with other components of metabolic syndrome on the risk of T2DM. Methods. A total of 15,717 eligible participants without baseline T2DM and aged 35 and over were included from a Chinese rural cohort. Cox proportional hazards regression models were used to estimate the association of HTGW and LAP with the incidence of T2DM, and the restricted cubic spline model was used to evaluate the dose-response association. Results. Overall, 867 new T2DM cases were diagnosed after 7.77 years of follow-up. Participants with HTGW had a higher hazard ratio for T2DM (hazard ratio (HR): 6.249, 95% confidence interval (CI): 5.199-7.511) after adjustment for potential confounders. The risk of incident T2DM was increased with quartiles 3 and 4 versus quartile 1 of LAP, and the adjusted HRs (95% CIs) were 2.903 (2.226-3.784) and 6.298 (4.911-8.077), respectively. There were additive interactions of HTGW (synergy index (SI): 1.678, 95% CI: 1.358-2.072) and high LAP (SI: 1.701, 95% CI: 1.406-2.059) with increased fasting plasma glucose (FPG) on the risk of T2DM. Additionally, a nonlinear ( P nonlinear < 0.001) dose-response association was found between LAP and T2DM. Conclusion. The subjects with HTGW and high LAP were at high risk of developing T2DM, and the association between LAP and the risk of T2DM may be nonlinear. Our study further demonstrates additive interactions of HTGW and high LAP with increased FPG on the risk of T2DM.

scholarly journals Avaliação do risco cardiovascular por meio do índice LAP em pacientes não obesas com síndrome dos ovários policísticos

2010 ◽  
Vol 54 (7) ◽  
pp. 630-635 ◽  
Author(s):  
Eduardo Caldas Costa ◽  
Joceline Cássia Ferezini de Sá ◽  
Elvira Maria Mafaldo Soares ◽  
Telma Maria Araújo Moura Lemos ◽  
Técia Maria de Oliveira Maranhão ◽  
...  
Keyword(s):  
Lipid Accumulation ◽  
Rio Grande ◽  
Lipid Accumulation Product

OBJETIVO: Analisar o risco cardiovascular de mulheres não obesas com síndrome dos ovários policísticos (SOP) por meio do índice LAP (lipid accumulation product). SUJEITOS E MÉTODOS: 283 pacientes (18-34 anos) alocadas do Hospital Universitário da Universidade Federal do Rio Grande do Norte, Natal-RN, foram divididas em quatro grupos: 1) SOP magras (n = 35); 2) saudáveis magras (n = 162); 3) SOP com sobrepeso (n = 28); 4) saudáveis com sobrepeso (n = 58). RESULTADOS: Pacientes com SOP apresentaram valores superiores do índice LAP em comparação às saudáveis: magras (22,26 vs. 15,87 cm.mmol/L; p = 0,007); sobrepeso (40,83 vs. 26,32 cm.mmol/L; p = 0,001). O percentual de mulheres acima do percentil 75 do índice LAP também foi superior nos subgrupos com SOP: magras (17,1 vs. 6,8%; p = 0,04); sobrepeso (37,5 vs. 13,8%; p = 0,01). CONCLUSÕES: Na amostra estudada, as pacientes com SOP apresentaram maior risco cardiovascular avaliado pelo índice LAP, quando comparadas a mulheres saudáveis, mesmo na ausência de obesidade.

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