Multicentric investigation of survival after Spanish emergency department discharge for acute heart failure

2012 ◽  
Vol 19 (3) ◽  
pp. 153-160 ◽  
Author(s):  
Òscar Miró ◽  
Víctor Gil ◽  
Pablo Herrero ◽  
Francisco Javier Martín-Sánchez ◽  
Javier Jacob ◽  
...  
Author(s):  
William B. Stubblefield ◽  
Cathy A. Jenkins ◽  
Dandan Liu ◽  
Alan B. Storrow ◽  
John A. Spertus ◽  
...  

Background: We conducted a secondary analysis of changes in the Kansas City Cardiomyopathy Questionnaire (KCCQ)-12 over 30 days in a randomized trial of self-care coaching versus structured usual care in patients with acute heart failure who were discharged from the emergency department. Methods: Patients in 15 emergency departments completed the KCCQ-12 at emergency department discharge and at 30 days. We compared change in KCCQ-12 scores between the intervention and usual care arms, adjusted for enrollment KCCQ-12 and demographic characteristics. We used linear regression to describe changes in KCCQ-12 summary scores and logistic regression to characterize clinically meaningful KCCQ-12 subdomain changes at 30 days. Results: There were 350 patients with both enrollment and 30-day KCCQ summary scores available; 166 allocated to usual care and 184 to the intervention arm. Median age was 64 years (interquartile range, 55–70), 37% were female participants, 63% were Black, median KCCQ-12 summary score at enrollment was 47 (interquartile range, 33–64). Self-care coaching resulted in significantly greater improvement in health status compared with structured usual care (5.4-point greater improvement, 95% CI, 1.12–9.68; P =0.01). Improvements in health status in the intervention arm were driven by improvements within the symptom frequency (adjusted odds ratio, 1.62 [95% CI, 1.01–2.59]) and quality of life (adjusted odds ratio, 2.39 [95% CI, 1.46–3.90]) subdomains. Conclusions: In this secondary analysis, patients with acute heart failure who received a tailored, self-care intervention after emergency department discharge had clinically significant improvements in health status at 30 days compared with structured usual care largely due to improvements within the symptom frequency and quality of life subdomains of the KCCQ-12. REGISTRATION: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT02519283.


2017 ◽  
Vol 24 (3) ◽  
pp. 298-307 ◽  
Author(s):  
Francisco Javier Martín‐Sánchez ◽  
Esther Rodríguez‐Adrada ◽  
Christian Mueller ◽  
María Teresa Vidán ◽  
Michael Christ ◽  
...  

2010 ◽  
Vol 17 (4) ◽  
pp. 197-202 ◽  
Author(s):  
Òscar Miró ◽  
Pere Llorens ◽  
Francisco Javier Martín-Sánchez ◽  
Pablo Herrero ◽  
Javier Jacob ◽  
...  

2016 ◽  
Vol 1 (1) ◽  
Author(s):  
Kori Sauser ◽  
Lora Alkhawam ◽  
Linda Pierchala ◽  
Peter S. Pang

Acute heart failure (AHF) may lead to subclinical tissue ischemia due to hypoperfusion from inadequate forward flow or congestion. The aim of the present study is to test whether lactate levels are elevated in emergency department (ED) patients with AHF. A prospective pilot study of ED AHF patients was conducted. Venous lactate level was measured at baseline and 6-12 hours after initial draw. Of the 50 patients enrolled, mean age was 65.3 years, 68% were male. Only 7 (14%) had an elevated lactate on either draw, with no differences in baseline characteristics between patients with and without elevated lactate. Patients with an elevated lactate had a higher mean heart rate (99 <em>vs</em> 81, P=0.03) and trended toward an increased rate of abnormal initial temperature (57 <em>vs</em> 23%, P=0.06). In this pilot study, only a minority of acute HF patients had an elevated lactate on presentation.


2018 ◽  
Vol 35 (5) ◽  
pp. 692-694
Author(s):  
Sajith Matthews ◽  
Phillip D. Levy ◽  
Mark Favot ◽  
Laura Gowland ◽  
Aiden Abidov

In Vivo ◽  
2018 ◽  
Vol 32 (4) ◽  
pp. 921-925 ◽  
Author(s):  
EFTYCHIOS SINIORAKIS ◽  
SPYRIDON ARVANITAKIS ◽  
CHRISTINA TSITSIMPIKOU ◽  
KONSTANTINOS TSAROUHAS ◽  
PANAGIOTIS TZEVELEKOS ◽  
...  

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