Update on innate immunity and perspectives on metabolite regulation in acute pancreatitis

2016 ◽  
Vol 32 (6) ◽  
pp. 507-512 ◽  
Author(s):  
Rafaz Hoque
Pancreatology ◽  
2011 ◽  
Vol 11 (5) ◽  
pp. 475-481 ◽  
Author(s):  
Vassiliki Mylona ◽  
Vassilios Koussoulas ◽  
Dimitrios Tzivras ◽  
Elias Makrygiannis ◽  
Panagiota Georgopoulou ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Shengchun Dang ◽  
Yao Shen ◽  
Kai Yin ◽  
Jianxin Zhang

Severe acute pancreatitis (SAP) can cause intestinal barrier dysfunction (IBD), which significantly increases the disease severity and risk of mortality. We hypothesized that the innate immunity- and inflammatory-related protein-triggering receptor expressed on myeloid cells-1 (TREM-1) contributes to this complication of SAP. Thus, we investigated the effect of TREM-1 pathway modulation on a rat model of pancreatitis-associated IBD. In this study we sought to clarify the role of TREM-1 in the pathophysiology of intestinal barrier dysfunction in SAP. Specifically, we evaluated levels of serum TREM-1 and membrane-bound TREM-1 in the intestine and pancreas from an animal model of experimentally induced SAP. TREM-1 pathway blockade by LP17 treatment may suppress pancreatitis-associated IBD and ameliorate the damage to the intestinal mucosa barrier.


Cytokine ◽  
2018 ◽  
Vol 103 ◽  
pp. 90-98 ◽  
Author(s):  
Shayal K. Chand ◽  
Ruma G. Singh ◽  
Sayali A. Pendharkar ◽  
Sakina H. Bharmal ◽  
Maxim S. Petrov

Suizo ◽  
2014 ◽  
Vol 29 (1) ◽  
pp. 45-50
Author(s):  
Tomohiro WATANABE ◽  
Yoshihisa TSUJI ◽  
Tsutomu CHIBA

Author(s):  
Murat Sarikaya ◽  
Nesibe Taser ◽  
Zeynal Dogan ◽  
Bilal Ergul ◽  
F. Irsel Tezer ◽  
...  

2001 ◽  
Vol 120 (5) ◽  
pp. A643-A644 ◽  
Author(s):  
D MEHTA ◽  
C FESTA ◽  
K DABNEY ◽  
M THEROUX ◽  
F MILLER

2001 ◽  
Vol 120 (5) ◽  
pp. A468-A469
Author(s):  
S RAHMAN ◽  
B AMMORI ◽  
I MARTIN ◽  
G BARCLAY ◽  
M LARVIN ◽  
...  

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