A Stroke Alert With Unexpected Outcome

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
David Gritsch ◽  
Ehab Harahsheh ◽  
Amir Mbonde ◽  
Kartik Mangipudi ◽  
Sara Dawit ◽  
...  
Keyword(s):  
2018 ◽  
Author(s):  
Caoimhe Bonner ◽  
Bonnie Grant ◽  
Anthony Pittathankal ◽  
Imran Syed ◽  
Edel Casey ◽  
...  

Materials ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3174
Author(s):  
Alan F. Murray ◽  
Evangelos Delivopoulos

Neuronal patterning on microfabricated architectures has developed rapidly over the past few years, together with the emergence of soft biocompatible materials and tissue engineering scaffolds. Previously, we introduced a patterning technique based on serum and the biopolymer parylene-C, achieving highly compliant growth of primary neurons and astrocytes on different geometries. Here, we expanded this technique and illustrated that neuralized cells derived from mouse embryonic stem cells (mESCs) followed stripes of variable widths with conformity equal to or higher than that of primary neurons and astrocytes. Our results indicate the presence of undifferentiated mESCs, which also conformed to the underlying patterns to a high degree. This is an exciting and unexpected outcome, as molecular mechanisms governing cell and ECM protein interactions are different in stem cells and primary cells. Our study enables further investigations into the development and electrophysiology of differentiating patterned neural stem cells.


2019 ◽  
Vol 129 (623) ◽  
pp. 2722-2744 ◽  
Author(s):  
Benjamin Born ◽  
Gernot J Müller ◽  
Moritz Schularick ◽  
Petr Sedláček

Abstract Economic nationalism is on the rise, but at what cost? We study this question using the unexpected outcome of the Brexit referendum vote as a natural macroeconomic experiment. Employing synthetic control methods, we first show that the Brexit vote has caused a UK output loss of 1.7% to 2.5% by year-end 2018. An expectations-augmented VAR suggests that these costs are, to a large extent, driven by a downward revision of growth expectations in response to the vote. Linking quasi-experimental identification to structural time-series estimation allows us not only to quantify the aggregate costs but also to understand the channels through which expected economic disintegration impacts the macroeconomy.


Spine ◽  
2001 ◽  
Vol 26 (13) ◽  
pp. 1425-1428 ◽  
Author(s):  
M. P. G. Bostrom ◽  
X. Yang ◽  
M. Kennan ◽  
H. Sandhu ◽  
E. Dicarlo ◽  
...  

2012 ◽  
Vol 13 (1) ◽  
Author(s):  
Yasuhiro Hashimoto ◽  
Atsushi Imai ◽  
Noriko Tokui ◽  
Atsushi Sasaki ◽  
Hisao Saitoh ◽  
...  

2022 ◽  
Vol 3 (2) ◽  

BACKGROUND Disruptions to the integrity of the inner table and trabeculae of the calvaria are rare phenomena. Increasingly rare is the phenomenon of herniation of brain parenchyma through the defects in the skull causing neurological deficit. Surgical intervention is commonly performed but is fraught with risk of brain tissue loss. OBSERVATIONS The authors present a case of a 78-year-old White male presenting with strokelike symptoms who was found to have an intradiploic encephalocele that was successfully treated with surgical intervention and neuroplastic reconstruction of the anatomical deficit. The patient had a marked recovery and had near-complete resolution of symptoms. LESSONS This notably rare phenomenon resolved with neurosurgical intervention, sparing the parenchyma, and provided the patient with perceivably normal contour of the head using a collaborative approach with neuroplastic intervention.


1989 ◽  
Vol 108 (3) ◽  
pp. 120-121 ◽  
Author(s):  
Neil S. Isaacs ◽  
Ghazi Najem El-Din ◽  
Michael G. B. Drew

2017 ◽  
Vol 17 (4) ◽  
pp. 947-968 ◽  
Author(s):  
Joshua C Gordon

AbstractOver the past 25 years, Sweden has gone from having one of the most generous unemployment benefit systems among the rich democracies to one of the least. This article advances a multi-causal explanation for this unexpected outcome. It shows how the benefit system became a target of successive right-wing governments due to its role in fostering social democratic hegemony. Employer groups, radicalized by the turbulent 1970s more profoundly than elsewhere, sought to undermine the system, and their abandonment of corporatism in the early 1990s limited unions’ capacity to restrain right-wing governments in retrenchment initiatives. Two further developments help to explain the surprising political resilience of the cuts: the emergence of a private (supplementary) insurance regime and a realignment of working-class voters from the Social Democrats to parties of the right, especially the nativist Sweden Democrats, in the context of a liberal refugee/asylum policy.


2020 ◽  
Vol 5 (3) ◽  
Author(s):  
Gerald West

An unexpected outcome of the work of the Ujamaa Centre for Community Development and Research with marginalised sectors is their sense that Contextual Bible Study resources provide them with an interpretive resilience that enables them to return to the churches that have marginalised them because they are unemployed, HIV-positive, or queer. This article explores the notion of ‘interpretive resilience’ and reflects on its capacity to reintegrate those who have been marginalised by dominant theologies. “Interpretive resilience” may have the capacity to construct forms of communal peace, but the article asks, what if what is required is ‘interpretive resistance’, which puts the sword to dominant interpretations in the quest for a more just peace? A particular case study, to do with issues of homosexuality, gives shape and substance to the theoretical reflections.1


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