Perineural Invasion in T1 Oral Squamous Cell Carcinoma Indicates the Need for Aggressive Elective Neck Dissection

2013 ◽  
Vol 37 (8) ◽  
pp. 1164-1172 ◽  
Author(s):  
Shyh-Kuan Tai ◽  
Wing-Yin Li ◽  
Muh-Hwa Yang ◽  
Pen-Yuan Chu ◽  
Yi-Fen Wang
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Perineural Invasion ◽  
Elective Neck Dissection

Elective Neck Dissection in T1N0M0 Oral Squamous Cell Carcinoma: When Is It Necessary?

2020 ◽  
Vol 78 (12) ◽  
pp. 2306-2315 ◽  
Author(s):  
Zhien Feng ◽  
Aoming Cheng ◽  
Shadi Alzahrani ◽  
Bo Li ◽  
Zhengxue Han ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Elective Neck Dissection

Elective neck dissection in early-stage oral squamous cell carcinoma—does it influence recurrence and survival?

Head & Neck ◽  
2006 ◽  
Vol 29 (1) ◽  
pp. 3-11 ◽  
Author(s):  
Ana Capote ◽  
Veronica Escorial ◽  
Mario F. Muñoz-Guerra ◽  
Francisco J. Rodríguez-Campo ◽  
Carlos Gamallo ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Early Stage ◽  
Elective Neck Dissection

scholarly journals Tumour infiltration depth ⩾4mm is an indication for an elective neck dissection in pT1cN0 oral squamous cell carcinoma

Oral Oncology ◽  
2012 ◽  
Vol 48 (4) ◽  
pp. 337-342 ◽  
Author(s):  
L.J. Melchers ◽  
E. Schuuring ◽  
B.A.C. van Dijk ◽  
G.H. de Bock ◽  
M.J.H. Witjes ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Elective Neck Dissection ◽  
Infiltration Depth ◽  
Tumour Infiltration

scholarly journals Elective neck dissection improves the survival of patients with T2N0M0 oral squamous cell carcinoma: a study of the SEER database

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Alimujiang Wushou ◽  
Feiluore Yibulayin ◽  
Lu Sheng ◽  
Yuan Luo ◽  
Zhi-cheng Yang
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Early Stage ◽  
The United States ◽  
Elective Neck Dissection ◽  
Rank Test ◽  
Observation Group

Abstract Background Treatment of clinical N0 neck tumours is controversial in early-stage oral squamous cell carcinoma (OSCC), possibly because T1N0M0 and T2N0M0 merge together at early stages. The purposes of this study were to compare survival outcomes only for T2N0M0 cases based upon treatment elective neck dissection versus neck observation. Methods T2N0M0 OSCC cases were identified in the Surveillance, Epidemiology, and End Results database of the United States National Cancer Institute between 2004 and 2015. Survival curves for different variable values were generated using Kaplan-Meier estimates and compared using the log-rank test. Variables that achieved significance at P < 0.05 were entered into multivariable analyses via the Cox proportional hazards multivariate regression. Results A total of 2857 patients were selected, and 2313 cases were available for disease specific survival (DSS). The 5-year and 10-year overall survival (OS) were 66.7 and 46% for patients receiving elective neck dissection (END), respectively, and 56.4 and 37.2% for patients with neck observation (P < 0.0001). The 5-year and 10-year DSS were 73.6 and 64% for the END group, respectively, versus 64.5 and 54.5% for the neck observation group (P < 0.0001). More importantly, performing END was independently associated with favourable DSS and OS for patients with T2N0M0 OSCC [hazard ratio (HR) = 0.769, P = 0.0069 for DSS; HR = 0.829, P = 0.0031 for OS, neck observation group as reference] according to multivariate survival analysis. Conclusion END is recommended for T2N0M0 OSCC cases and it is associated with improved DSS and OS.

scholarly journals Elective neck dissection in oral squamous cell carcinoma: Past, present and future

Oral Oncology ◽  
2019 ◽  
Vol 90 ◽  
pp. 87-93 ◽  
Author(s):  
Remco de Bree ◽  
Robert P. Takes ◽  
Jatin P. Shah ◽  
Marc Hamoir ◽  
Luiz P. Kowalski ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Elective Neck Dissection
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