Rainfall Infiltration Process of a Rock Slope with Considering the Heterogeneity of Saturated Hydraulic Conductivity

In order to analyze the effects of rainfall events on the stability of an open-pit rock slope, with considering the spatial variability of saturated hydraulic conductivity, based on the unsaturated seepage theory and the random filed theory, modified functions of the unit saturation, the hydraulic conductivity (k), and the shear strength parameters are established for unsaturated slope, by using FISH and the non-intrusive stochastic method. A saturated-unsaturated seepage random field model is proposed. And then the impacts of the rainfall intensity, the rainfall duration, and the spatial variability of saturated hydraulic conductivity (ks) on the infiltration process and stability of the unsaturated rock slope are analyzed. The results show that the proposed model can estimate rainfall infiltration of rock slope accurately. Rainfall mainly affects the seepage field in the shallow layer of the slope, where a transient saturated zone can be formed. With the development of the rainfall duration, the weight of the rock mass increased, the matric suction reduced, the negative pore pressure, the degree of saturation, and the infiltration depth of the rock slope increased, and the water in the slope root connects with the initial water table gradually, the unsaturated zone shrinks, which causes the safety factor of the model decreases, but the trend of change slows down gradually. As the rainfall intensity strengthened, the infiltration depth increased and the safety factor of the slope reduced, while the changing rate increases first and then decreases. Increasing the correlation length of k can reduces the infiltration depth and safety factor of the slope. Increasing the variation coefficient of k will increase the infiltration depth, while the safety factor of the slope decreases. The infiltration depth and safety factor of the slope are most affected by rainfall duration, but its sensitivity to the variability coefficient of k will be strengthened when the rainfall intensity exceeds the infiltration capacity. This conclusion can provide reference significance for the risk estimation of slope geological hazards, which are induced by the rainfall infiltration.

Infiltration Depth of Mineral Particles in Gravel-Bed Rivers

This article discusses the results of an experimental study of a spill of mineral particles in gravel-bed rivers due to mining accidents. The purpose of this research is to characterize the dynamics of the fine mining particles spilled on a bed of immobilized gravel as a hyper-concentrated mixture and to experimentally characterize the infiltration phenomenon. We analyzed the type of infiltration considering the dimensionless coarse to fine particle size relationship, the dimensionless weight of the fine particles, the relative density of the particles, and the relationship between the subsurface and surface velocities, in addition to the densimetric Froude and Reynolds numbers of the fine particles. We found that the dimensionless infiltration depth is not associated with hydraulic parameters or the weight of the fine sediment spilled; however, fine sediment deposition decreases with depth, and infiltration depth may increase if subsurface flow decreases over time. Finally, a relationship of the dimensionless maximum infiltration depth with the relative density of the mining particles, the ratio of the bed sediment and the mining particles sizes, and the ratio between the subsurface and surface velocities is established.

Evaluation of the role of soluble B7-H3 in association with membrane B7-H3 expression in gastric adenocarcinoma

BACKGROUND and OBJECTIVE: Gastric adenocarcinoma (GAC) is one of the most common malignancies. Increasing data have indicated a correlation between soluble B7-H3 (sB7-H3) levels and tumor malignancies. In this study, we aim to investigate the level of soluble B7-H3 in serum of GAC patients. Further, we analyze the correlation between sB7-H3 level and tissue B7-H3 expression and explore the clinical evaluation value of sB7-H3 associated with pathological characteristics and prognosis of GAC patients. METHODS: One hundred and twenty-eight serum and tissue samples of GAC 20 serum and tissue samples of gastritis patients and 77 serum, 5 tissue samples of healthy controls were collected. The serum levels of sB7-H3 were detected by Enzyme-linked immunosorbent assay (ELISA), while the expression of membrane B7-H3 (mB7-H3) and Ki67 were evaluated by immunohistochemistry. The correlation between sB7-H3 and mB7-H3, sB7-H3 and Ki67, sB7-H3 or mB7-H3 and clinical features were analyzed by Pearson’s Chi-square test. RESULTS: Both serum level of sB7-H3 and tissue B7-H3 of GAC patients were significantly higher than those of gastritis patients and healthy controls. sB7-H3 level was correlated with total B7-H3 expression in tissues (r= 0.2801, P= 0.0014). Notably, the concentration of sB7-H3 was correlated with its expression of membrane form in tumor cells (r= 0.3251, P= 0.002) while not in stromal cells (r= 0.07676, P= 0.3891). Moreover, the levels of sB7-H3 in patients with TNM stage III/IV or with Infiltration depth T3/T4 or with lymph node metastasis were significantly higher than those of patients with TNM stage I/II (P= 0.0020) or with Infiltration depth T1/T2 (P= 0.0169) or with no lymph node metastasis (P= 0.0086). Tumor B7-H3 score, but not stromal B7-H3 score, in patients with TNM stage III/IV or with lymph node metastasis was significantly higher than those with TNM stage I/II (P= 0.0150) or with no lymph node metastasis (P= 0.182). CONCLUSIONS: Soluble B7-H3 level may reflect the tissue B7-H3 expression on tumor cells of GAC tissues. Elevated level of sB7-H3 in serum suggests poor clinical pathological characteristics of GAC patients.

Development and Calibration of Automated Multiple-Ring Infiltrometer

An automatic triple-ring infiltrometer was developed using a set of pre-set sensors and transducer (AP 403, AP 404, AP 405 and AP 406, RAP001 and RAP002). The aluminum probe sensors were graduated and arranged in series to monitor the rate at which water is infiltrating into the soil layer. The working principle of automatic triple-ring infiltrometer was developed using six probes with depth calibration of 1.0mm, 26.7 mm, 12.4 mm, and 12.7 mm, respectively. The result obtained showed strong agreement with a coefficient of determination R2= 0.963, indicating positive proportionality between cumulative infiltration and time taken for the water to infiltrate at different depths. The instrument has a measuring accuracy of ± 0.3mm infiltration depth. The device works effectively under biochar amended soil and other soil formations with high precision. Accurate infiltration data generated by the instrument would be applied to estimate the depth of water available to plant and predict possible agricultural drought.

Development and Calibration of Automated Multiple-Ring Infiltrometer

An automatic triple-ring infiltrometer was developed using a set of pre-set sensors and transducer (AP 403, AP 404, AP 405 and AP 406, RAP001 and RAP002). The aluminum probe sensors were graduated and arranged in series to monitor the rate at which water is infiltrating into the soil layer. The working principle of automatic triple-ring infiltrometer was developed using six probes with depth calibration of 1.0mm, 26.7 mm, 12.4 mm, and 12.7 mm, respectively. The result obtained showed strong agreement with a coefficient of determination R2= 0.963, indicating positive proportionality between cumulative infiltration and time taken for the water to infiltrate at different depths. The instrument has a measuring accuracy of ± 0.3mm infiltration depth. The device works effectively under biochar amended soil and other soil formations with high precision. Accurate infiltration data generated by the instrument would be applied to estimate the depth of water available to plant and predict possible agricultural drought.

Clinicopathological Risk Factors for Contralateral Lymph Node Metastases in Intraoral Squamous Cell Carcinoma: A Study of 331 Cases

The current study aimed to examine the effects of clinicopathological factors, including the region, midline involvement, T classification, histological grade, and differentiation of the tumor on the rate of contralateral lymph node metastasis for oral squamous cell carcinoma and to assess their effects on survival rates. A total of 331 patients with intraoral squamous cell carcinomas were included. The influence of tumor location, T status, midline involvement, tumor grading, and the infiltration depth of the tumor on the pattern of metastasis was evaluated. Additionally, the effect of contralateral metastases on the prognosis was examined. Metastases of the contralateral side occurred most frequently in squamous cell carcinomas of the palate and floor of the mouth. Furthermore, tumors with a high T status resulted in significantly higher rates of contralateral metastases. Similarly, the midline involvement, tumor grading, existing ipsilateral metastases, and the infiltration depth of the tumor had a highly significant influence on the development of lymph node metastases on the opposite side. Oral squamous cell carcinomas require a patient-specific decision. There is an ongoing need for further prospective studies to confirm the validity of the prognostic factors described herein.

Clinical study of the clinical characteristics and prognosis of 1219 cases of endometrial cancer with lymph node metastasis

To analyze the clinical characteristics and prognosis of endometrial cancer patients with lymph node metastasis to provide a reference for lymphadenectomy in endometrial cancer. The data used in this study were extracted from a tertiary hospital in Guangxi, China based on the hospital information system. 1219 patients with endometrial malignancy who were treated in our hospital. The lymph node metastasis rate was 9.8%. The metastasis rate of the abdominal aorta + pelvic lymph nodes (56.7%) was significantly higher than that of the pelvic (24.2%) or para-aortic (19.2%) lymph nodes alone. The proportion of postmenopausal patients with lymph node metastasis was higher than that of premenopausal patients. The proportion of patients with lymph node metastasis with vaginal and uterus involvement, HPV detection, Thinprep Cytologic Testresults, CRP level <10 ug/mL, G3 tumor grade, postoperative pathology indicating cervical invasion, lymphovascular invasion, and muscular infiltration depth > 1/2 was higher than that of patients without lymph node metastasis. The proportion of endometrial cancer patients with lymph node metastasis with CA125 ≥ 35 U/ml was higher than that of those with CA125 < 35 U/ml. The lymph node-positive rate is related to tissue differentiation, lymphangitic infiltration, cervical invasion, muscle infiltration depth > 1/2, and CA125 level. The metastasis rate of pelvic and para-aortic lymph nodes is higher than that of pelvic lymph nodes or para-aortic lymph nodes alone. There was no statistically significant difference in the overall survival rate among the three groups.

Response characteristics of soil moisture to rainfall for a single grass vegetation in the urban area A case of regional grassland in Yangzhou City

A regional grassland with Bermudagrass in Yangzhou City of China was adopted as the study location. Based on the analysis of the different rainfall events and soil water content data in the same periods, the response characteristics of infiltration to rainfall were revealed in a certain degree. The surface resistance parameters (rs) are calibrated according to the soil water content at the depths of a range for 0-30 cm and of the root layer (0-10 cm). Penman-Monteith (P-M) equation was adopted to estimated the hourly evapotranspiration (ET) over the Bermudagrass lawn of the soil layers for the depths of 0-30 cm (ET30) and 0-10 cm (ET10), respectively. Applicability of HYDRUS-1D model for simulating soil water content at different depths was validated. The results indicated that the infiltration depth generally varies with the rainfall event grade, and on the whole, the infiltration depth increases with the improvement of amount of rainfall; the response time for the soil water content in root layer is much shorter with the less soil water content in the topsoil (0-5.5 cm); the increase rate of soil water content raised with increasing of rainfall intensity in the state of unsaturation; ET10 accounts for about 78% of ET30, which demonstrates the water consumed by ET is mainly provided by the soil water in the root layer. the rationality of the results of different rainfall events and infiltration depth achieved by the analysis of the observed data were verified via numerical simulation using Hydrus-1D.