Ovarian Combined Brenner Tumor, Mucinous Cystadenoma and Struma Ovarii

Mucinous cystadenoma arises from the totipotent surface epithelium of the ovary. Its association with Brenner tumor suggests its origin as mucinous metaplasia of the epithelioid cells. The chance of malignancy is 5–10 percent. Patients usually present with abruptly increasing abdominal mass. Cystectomy is the management of choice in these cases. It was managed by laparoscopy.

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Borderline Brenner Tumor of the Ovary Coexisting With an Ovarian Mucinous Cystadenoma With Focal Atypical Epithelial Proliferation: A Rare Case With Review of the Literature

International Journal of Surgical Pathology ◽

10.1177/1066896921999459 ◽

2021 ◽

pp. 106689692199945

Author(s):

Christine J. Salibay ◽

Valentina Zanfagnin ◽

Heather Miller ◽

Saloni Walia ◽

Laurie L. Brunette ◽

...

Keyword(s):

Mucinous Cystadenoma ◽

Clinicopathological Characteristics ◽

Clinicopathological Features ◽

Review Of The Literature ◽

Epithelial Proliferation ◽

Unique Case ◽

Mucinous Neoplasm ◽

Brenner Tumor ◽

Clinical Presentations ◽

Brenner Tumors

Ovarian Brenner tumors, accounting for ∼5% of overall ovarian epithelial neoplasm, are often reported in association with mucinous neoplasm. Histogenetically, the two tumors are thought to arise from similar precursors. To date, fewer than 60 borderline Brenner tumors alone have been reported, and the concomitant presence of atypical proliferative components in Brenner and mucinous tumors is even rarer. Therefore, the clinicopathological characteristics and prognosis of patients with the borderline Brenner tumors alone or coexisting with mucinous neoplasm are extremely limited. Herein, we report a unique case of a 53-year-old woman with a unilateral ovarian borderline Brenner tumor associated with focal atypical mucinous epithelial proliferation and her clinical presentations. The clinicopathological features of the tumor are documented and the literature review along with the clinical molecular advances are summarized in this study.

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Predominant Brenner Tumor Combined with Struma Ovarii Containing a Papillary Microcarcinoma Associated with Benign Peritoneal Strumosis: Report of a Case and Histologic Features

Endocrine Pathology ◽

10.1007/s12022-010-9123-x ◽

2010 ◽

Vol 21 (3) ◽

pp. 199-203 ◽

Cited By ~ 5

Author(s):

Simone Sibio ◽

Francesco Borrini ◽

Paolo Sammartino ◽

Fabio Accarpio ◽

Daniele Biacchi ◽

...

Keyword(s):

Struma Ovarii ◽

Papillary Microcarcinoma ◽

Brenner Tumor

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Collision Tumors in Ovary: Case Series and Literature Review

Journal of Surgical Oncology ◽

10.31487/j.jso.2019.03.06 ◽

2019 ◽

pp. 1-10

Author(s):

Borges A ◽

Loddo A ◽

Martins A ◽

Peiretti M ◽

Fanni D ◽

...

Keyword(s):

Literature Review ◽

Ovarian Tumor ◽

Case Series ◽

Mucinous Cystadenoma ◽

Cystic Teratoma ◽

Mature Cystic Teratoma ◽

Adequate Treatment ◽

Collision Tumors ◽

Brenner Tumor ◽

Malignant Lesions

Histologically distinct tumors that coexist in an organ without any histological admixture at their interface are denominated collision tumors. We report 3 cases of colliding mature cystic teratoma with mucinous cystadenoma and a case of mature cystic teratoma colliding with benign Brenner tumor in the ovary. We also provide a literature review based on 35 previously published ovarian collision cases. Ovarian tumors from all classes, benign, borderline and malignant lesions may collide. Both our case series and the literature review indicate that ovarian tumor collisions tend to be clinically and ultrasonographically/radiologically unrecognized. The awareness among surgeons, radiologists and pathologists of this rare phenomenon and histological recognition are crucial in order to offer adequate treatment to patients. There is a need to identify novel and more specific imaging clues pointing towards collision tumors in the ovary.

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A Rare Case of Giant Ovarian Serous Cystadenoma presenting as Psuedo-Meigs Syndrome

Obstetrics Gynecology and Reproductive Sciences ◽

10.31579/2578-8965/056 ◽

2021 ◽

Vol 5 (2) ◽

pp. 01-05

Author(s):

Richmond Ronald Gomes

Keyword(s):

Gold Standard ◽

Rare Case ◽

Standard Treatment ◽

Mucinous Cystadenoma ◽

Rare Condition ◽

Serous Cystadenoma ◽

Struma Ovarii ◽

Tumor Removal ◽

Definition Of ◽

Leiomyoma Of The Uterus

Meigs’ syndrome is a rare condition characterized by the presence of a benign fibroma of the ovary, ascites and pleural effusion. Other benign cysts of the ovary (such as struma ovarii, mucinous cystadenoma, serous cystadenoma and teratomas), leiomyoma of the uterus, and secondary metastatic tumours to ovary if associated with hydro thorax and ascites are referred to as ‘Pseudo‐Meigs” syndrome. It very uncommon and diagnosis is made difficult by symptoms that usually mimic disseminated malignancy or tuberculosis. The gold standard treatment is laparotomy and, by definition of the syndrome, after tumor removal, the symptoms resolves and the patients become asymptomatic. We presented an 18 years old girl with giant ovarian serous cystadenoma with associated pseudo-meigs syndrome, successfully managed in a low resources setting.

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Bilateral Brenner tumor of ovary with associated unilateral mucinous cystadenoma: a case report

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20191981 ◽

2019 ◽

Vol 8 (5) ◽

pp. 2122

Author(s):

Natasha Mittal ◽

Bhaskar Das ◽

Seema Manuja ◽

Renu Gupta

Keyword(s):

Incidental Finding ◽

Transitional Cell ◽

Mucinous Cystadenoma ◽

Pathological Examination ◽

Benign Tumors ◽

Surgical Removal ◽

Brenner Tumor ◽

Brenner Tumors ◽

Mucinous Cystadenomas ◽

Transitional Cell Tumors

Brenner tumors are rare ovarian tumors, which are a subgroup of transitional cell tumors of ovary. Most of these tumors are benign presenting as incidental unilateral masses in postmenopausal age group. Only 5-7% cases are bilateral. These tumors are mostly small, solid and asymptomatic, seen commonly in association with mucinous cystadenomas of ovary. In such cases they may attain a massive size. Specific diagnosis of Brenner tumor is difficult using imaging studies and can be definitely diagnosed only on pathological examination. Surgical removal is usually curative for benign tumors. We present a rare case of bilateral Brenner tumor of ovary with associated unilateral mucinous cystadenoma in which bilateral Brenner tumor was a rare incidental finding on pathological examinatio

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Pure Uterine Lipoma with a Combined Mucinous Cystic and Brenner Ovarian Tumor in a Postmenopausal Woman: A Case Report and Review of the Literature

Case Reports in Obstetrics and Gynecology ◽

10.1155/2021/5512951 ◽

2021 ◽

Vol 2021 ◽

pp. 1-4

Author(s):

Toshimitsu Tohya ◽

Mariko Tominaga ◽

Tomoko Honda

Keyword(s):

Postmenopausal Woman ◽

Ovarian Tumor ◽

Relevant Literature ◽

Mucinous Cystadenoma ◽

Cystic Tumor ◽

Solid Portion ◽

Uterine Tumors ◽

Brenner Tumor ◽

Uterine Lipoma ◽

Lipomatous Tumors

Lipomatous tumors are rare among uterine mesenchymal tumors. Due to their rarity, information on the clinical development and histological origin are lacking. We report a pure uterine lipoma and present a review of the relevant literature. We encountered a 72-year-old postmenopausal woman who was referred to our hospital. Computed tomography (CT) and magnetic resonance imaging (MRI) examinations revealed degenerative uterine tumors and a left ovarian cystic tumor with a solid portion. Total hysterectomy and bilateral salpingo-oophorectomy were performed, and postoperative histological examination revealed a uterine lipoma and adenomyosis. The cystic portion was a mucinous cystadenoma, and the solid portion was classified as a Brenner tumor. The postoperative course was uneventful, and the patient was discharged and remained well until follow-up. Our observations suggest that imaging examinations are sufficient for the diagnosis of uterine lipomatous tumors. To the best of our knowledge, the coexistence of a pure uterine lipoma and a mucinous Brenner ovarian tumor has not been documented in the existing literature. The histogenesis of uterine lipomas remains unclear. However, our results, and those from the existing literature, indicate that the mesenchymal stem cells surrounding the perivascular tissue may be implicated, because lipomas of the skin are reported to originate from these cells.

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