scholarly journals Bilateral Brenner tumor of ovary with associated unilateral mucinous cystadenoma: a case report

2019 ◽  
Vol 8 (5) ◽  
pp. 2122
Author(s):  
Natasha Mittal ◽  
Bhaskar Das ◽  
Seema Manuja ◽  
Renu Gupta
Keyword(s):  
Incidental Finding ◽  
Transitional Cell ◽  
Mucinous Cystadenoma ◽  
Pathological Examination ◽  
Benign Tumors ◽  
Surgical Removal ◽  
Brenner Tumor ◽  
Brenner Tumors ◽  
Mucinous Cystadenomas ◽  
Transitional Cell Tumors

Brenner tumors are rare ovarian tumors, which are a subgroup of transitional cell tumors of ovary. Most of these tumors are benign presenting as incidental unilateral masses in postmenopausal age group. Only 5-7% cases are bilateral. These tumors are mostly small, solid and asymptomatic, seen commonly in association with mucinous cystadenomas of ovary. In such cases they may attain a massive size. Specific diagnosis of Brenner tumor is difficult using imaging studies and can be definitely diagnosed only on pathological examination. Surgical removal is usually curative for benign tumors. We present a rare case of bilateral Brenner tumor of ovary with associated unilateral mucinous cystadenoma in which bilateral Brenner tumor was a rare incidental finding on pathological examinatio

Borderline Brenner Tumor of the Ovary Coexisting With an Ovarian Mucinous Cystadenoma With Focal Atypical Epithelial Proliferation: A Rare Case With Review of the Literature

2021 ◽  
pp. 106689692199945
Author(s):  
Christine J. Salibay ◽  
Valentina Zanfagnin ◽  
Heather Miller ◽  
Saloni Walia ◽  
Laurie L. Brunette ◽  
...  
Keyword(s):  
Mucinous Cystadenoma ◽  
Clinicopathological Characteristics ◽  
Clinicopathological Features ◽  
Review Of The Literature ◽  
Epithelial Proliferation ◽  
Unique Case ◽  
Mucinous Neoplasm ◽  
Brenner Tumor ◽  
Clinical Presentations ◽  
Brenner Tumors

Ovarian Brenner tumors, accounting for ∼5% of overall ovarian epithelial neoplasm, are often reported in association with mucinous neoplasm. Histogenetically, the two tumors are thought to arise from similar precursors. To date, fewer than 60 borderline Brenner tumors alone have been reported, and the concomitant presence of atypical proliferative components in Brenner and mucinous tumors is even rarer. Therefore, the clinicopathological characteristics and prognosis of patients with the borderline Brenner tumors alone or coexisting with mucinous neoplasm are extremely limited. Herein, we report a unique case of a 53-year-old woman with a unilateral ovarian borderline Brenner tumor associated with focal atypical mucinous epithelial proliferation and her clinical presentations. The clinicopathological features of the tumor are documented and the literature review along with the clinical molecular advances are summarized in this study.

scholarly journals A rare presentation of benign Brenner tumor of ovary: a case report

2018 ◽  
Vol 7 (7) ◽  
pp. 2971
Author(s):  
Sumathi Periasamy ◽  
Subha Sivagami Sengodan ◽  
Devipriya . ◽  
Anbarasi Pandian
Keyword(s):  
Abdominal Pain ◽  
Ovarian Tumor ◽  
Ovarian Neoplasms ◽  
Pelvic Mass ◽  
Ovarian Tumors ◽  
Pathological Examination ◽  
Rare Presentation ◽  
Brenner Tumor ◽  
Benign Nature ◽  
Brenner Tumors

Brenner tumors are rare ovarian tumors accounting for 2-3% of all ovarian neoplasms and about 2% of these tumors are borderline (proliferating) or malignant. These tumors are commonly seen in 4th-8th decades of life with a peak in late 40s and early 50s. Benign Brenner tumors are usually small, <2cm in diameter and often detected incidentally during surgery or on pathological examination. Authors report a case of a large, calcified benign Brenner tumor in a 55-year-old postmenopausal woman who presented with complaint of abdominal pain and mass in abdomen. Imaging revealed large complex solid cystic pelvic mass -peritoneal fibrosarcoma. She underwent laparotomy which revealed huge Brenner tumor weighing 9kg arising from left uterine cornual end extending up to epigastric region. Myomectomy and hysterectomy with bilateral salphingo oophorectomy, omentectomy done and the specimen was sent for histopathological and immunohistochemistry study which revealed benign Brenner tumor. Brenner tumors are rare ovarian neoplasms accounting for 2-3% of all ovarian tumors. Benign Brenner tumors are usually small and solid whereas borderline and malignant Brenner tumors are usually larger and cystic with solid areas. But it is possible to have a completely benign large Brenner tumor. Therefore, benign nature of the lesion should not be excluded even when the ovarian tumor is very large.

scholarly journals DIAGNOSIS AND MANAGEMENT OF PANCREATIC MUCINOUS CYSTADENOMA

2015 ◽  
Vol 2 (2) ◽  
pp. 63-67
Author(s):  
Lidia Ladea ◽  
Andreea Nicoleta Costache ◽  
F. C. Blăjuț ◽  
V. Tomulescu
Keyword(s):  
Acute Pancreatitis ◽  
Therapeutic Option ◽  
Malignant Lesion ◽  
Mucinous Cystadenoma ◽  
Rare Condition ◽  
The Body ◽  
Pancreatic Cysts ◽  
Benign Tumors ◽  
Recurrent Acute Pancreatitis ◽  
Mucinous Cystadenomas

Pancreatic mucinous cystadenomas (MCAs) are considered to be benign tumors with a high risk of malignant progression. The pancreatic mucinous cystadenoma is considered to be a rare condition that may lead to pancreatic cancer when not surgically resected. MCAs represent 9.7% of all neoplastic pancreatic cysts. The male:female ratio of MCAs is 1:10. The condition appears mostly in women, mean age in the 5th decade. The cyst is restricted by a fibrous capsule of variable consistency and has usually no communication with the pancreatic ductal system. The MCAs are located mostly in the body or tail of the pancreas. The MCAs located in the head of the pancreas are more likely to be malignant. Complete surgical resection is the recommended therapeutic option. We present a case of a 59-year-old female patient admitted in the Departemt of Surgery and Liver Transplatation of Fundeni Clinical Institute for recurrent episodes of acute pancreatitis. After a thorough investigation was performed, the CT-examination showed a pancreatic mass, located in the tail, measuring 30/40mm. Because the CT aspect was specific for a cystic-like lesion, surgery was recommended. The patient underwent a laparoscopic caudal splenopancreatectomy with a favorable postoperative evolution. The particularity of the case comes from the patient’s clinical presentation, with recurrent acute pancreatitis and the imagistic aspect (ultrasound and CT) that initially suggested a pseudocystic-like lesion, but the elevated CA 15-3 and further elaborated examinations indicated a possible malignant lesion.

Pilocytic Astrocytomas in Children: Prognostic Factors—A Retrospective Study of 80 Cases

Neurosurgery ◽  
2003 ◽  
Vol 53 (3) ◽  
pp. 544-555 ◽  
Author(s):  
Carla Fernandez ◽  
Dominique Figarella-Branger ◽  
Nadine Girard ◽  
Corinne Bouvier-Labit ◽  
Joanny Gouvernet ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Survival Rates ◽  
Progression Free Survival ◽  
Partial Resection ◽  
Pathological Examination ◽  
Benign Tumors ◽  
Surgical Removal ◽  
Clinicopathological Factors ◽  
Pilocytic Astrocytomas ◽  
Worse Prognosis

Abstract OBJECTIVE Pilocytic astrocytomas (PA) are Grade I brain tumors characterized by an excellent prognosis. In some cases, however, the patient has a bad outcome. The aim of our study was to search for the clinicopathological factors underlying the prognosis for patients with this disease. METHODS We reviewed the clinical, neuroradiological, and histopathological features of 80 PAs (33 cerebellar, 18 optochiasmatic, 16 brainstem, 7 spinal cord, 3 thalamic, 2 optic nerve, and 1 hemispheric) in pediatric patients. RESULTS Pathological examination revealed 58 classic PAs and 20 pilomyxoid astrocytomas, which are a histological variant of PAs. Two cases remained unclassified. The mean overall follow-up period was 58 months, the 5-year progression-free survival rate was 75%, and the 5-year survival rates were 100 and 92% after total and partial removal. Univariate statistical analysis revealed that partial resection, optochiasmatic PA localization, and pilomyxoid variant were associated with a worse prognosis, but the latter two parameters were too closely related to the extent of resection to be independent prognostic factors in multivariate analysis. Among the patients who underwent partial surgical removal, only invasion of the surrounding structures was related to prognosis. CONCLUSION PAs are benign tumors, but some clinicopathological factors, such as partial resection, optochiasmatic location, invasion of surrounding structures, and the pilomyxoid variant, have a worse prognosis.

scholarly journals HYDATIC CYST OF THE LIVER OR HEPATIC MUCINOUS CYSTADENOMA

2021 ◽  
Vol 9 (11) ◽  
pp. 35-39
Author(s):  
Tamour H. ◽  
◽  
Ait Belaid W. ◽  
Ahbala T. ◽  
Rabbani K. ◽  
...  
Keyword(s):  
General Surgery ◽  
Mucinous Cystadenoma ◽  
Benign Tumors ◽  
Hydatid Cysts ◽  
Hepatic Hydatid Cyst ◽  
Cystic Neoplasms ◽  
Hydatic Cyst ◽  
Mucinous Cystadenomas ◽  
Surgery Department ◽  
Hepatic Hydatid

Mucinous cystadenomas of the liver are rare cystic neoplasms, often mistaken for simple cysts or hydatid cysts of the liver. They are generally benign tumors, often discovered incidentally on imaging or during independent surgeries. Despite their tendency to grow slowly, mucinous cystadenomas of the liver can reach symptomatic dimensions. And given their potential for malignant transformation into mucinous cystadenocarcinomas, a misdiagnosis can have serious secondary consequences. We report the case of a 55-year-old woman with chronic right hypochondrium pain in whom a mucinous cystadenoma of the liver was accidentally discovered during surgery for hepatic hydatid cyst at the general surgery department at the ARRAZI Hospital - UHC Mohammed VI in Marrakech, Morocco.

Exploring the Histogenesis of Ovarian Mucinous and Transitional Cell (Brenner) Neoplasms and Their Relationship With Walthard Cell Nests: A Study of 120 Tumors

2008 ◽  
Vol 132 (11) ◽  
pp. 1753-1760 ◽  
Author(s):  
Jeffrey D. Seidman ◽  
Fatemeh Khedmati
Keyword(s):  
Strong Association ◽  
Transitional Cell ◽  
Relative Volume ◽  
Size Distributions ◽  
Mucinous Component ◽  
Cell Components ◽  
The Face ◽  
Brenner Tumors ◽  
Mucinous Cystadenomas ◽  
Combined Tumors

Abstract Context.—The origin of and relationship between ovarian mucinous and transitional cell (Brenner) neoplasms are enigmatic. The reported association ranges from 1% to 16%, and whether there is an association with Walthard cell nests is unknown. Objective.—To clarify the histologic relationship between mucinous and Brenner tumors. Design.—A total of 40 mucinous cystadenomas, 67 Brenner tumors, and 13 combined tumors were studied. Peritoneal surfaces were examined for Walthard nests in 83 patients compared with 272 controls. Results.—A total of 25% of tumors with a mucinous component contained a Brenner component, and 16% of tumors with a Brenner component contained a mucinous component. Most calcifications were spiculated (nonpsammomatous). In 6 combined tumors, the relative volume of the 2 components was less than 1:3000 (transitional-mucinous). Walthard nests were found in 50% of patients with Brenner tumors and 59% of patients with mucinous tumors. This was significantly higher than the 28% found in controls (P = .002 and P &lt; .001, respectively). The number of fallopian tube blocks examined was correlated with the likelihood of finding Walthard nests, and accordingly, sampling accounted for 39% of the increase with Brenner tumors but strengthened the association with mucinous tumors. Conclusions.—The strong association of mucinous and transitional cell components, similar type of calcification, complementary size distributions, and frequent identification of a transitional component in the face of an exceedingly small estimated proportion of that component suggest that this association has been underestimated. The association of Brenner tumors with Walthard nests, although significant, appears weak and not strongly supportive of a histogenetic relationship. The stronger association of Walthard nests with mucinous tumors remains unexplained.

scholarly journals Malignant Brenner Tumor of Ovary

2014 ◽  
Vol 6 (2) ◽  
pp. 126-128
Author(s):  
Shikha Joshi ◽  
Prabhjot Ubeja
Keyword(s):  
Reproductive Tract ◽  
Malignant Tumors ◽  
Transitional Cell ◽  
Female Reproductive Tract ◽  
Gravid Uterus ◽  
Brenner Tumor ◽  
Pouch Of Douglas ◽  
Brenner Tumors ◽  
Exact Size ◽  
Irregular Mass

ABSTRACT Introduction Ovarian carcinoma remains the most lethal disease of the female reproductive tract and most difficult to diagnose early. Brenner tumor of ovary is a relatively uncommon neoplasm constituting 1.4 to 2.5% of all ovarian tumors. In vast majority of cases, these tumor are benign, only 2.5% being malignant. Case Report A 46 years old parous menopausal female presented with complains of pain in abdomen since 2 months and lump in right iliac region. Per abdomen examination showed irregular mass of variable consistency with 16 to 18 weeks gravid uterus size arising from pelvis. On per vaginum examination, firm to hard mass was felt in the posterior and lateral fornices exact size of which could not be determined. Per rectal examination revealed hard nodules in Pouch of Douglas (POD). Ovarian cytoreduction surgery was performed. Omentectomy was performed. Histopathology showed malignant Brenner tumor (transitional cell carcinoma). Conclusion Although Brenner tumors are rare and the majority of them are benign, the correct histological diagnosis with identification of the small proportion of malignant tumors allows the extent of the operation to be needed. How to cite this article Hariharan C, Joshi S, Ubeja P. Malignant Brenner Tumor of Ovary. J South Asian Feder Obst Gynae 2014;6(2):126-128.

scholarly journals Radiographic Features of a Benign Mixed Brenner Tumor and Mucinous Cystadenoma: A Rarely Identified Ovarian Neoplasm on Imaging

2020 ◽  
Vol 10 ◽  
pp. 22
Author(s):  
Mitchell P. Wilson ◽  
Prayash Katlariwala ◽  
June Hwang ◽  
Gavin Low
Keyword(s):  
Mucinous Cystadenoma ◽  
Ovarian Neoplasm ◽  
Imaging Features ◽  
Radiographic Features ◽  
Brenner Tumor ◽  
Mucinous Cystadenomas

Imaging features of benign mixed Brenner tumor and mucinous cystadenomas are rarely reported. This report aims to describe the case of a benign mixed Brenner tumor and mucinous cystadenoma with a dominant Brenner tumor component and to review the typical imaging features of this ovarian neoplasm.

Paratesticular Mucinous Cystadenoma Arising From an Oviduct-Like Müllerian Remnant: A Case Report and Review of the Literature

2006 ◽  
Vol 130 (11) ◽  
pp. 1715-1717 ◽  
Author(s):  
Vedran Uschuplich ◽  
John R. Hilsenbeck ◽  
Claude R. Velasco
Keyword(s):  
Case Reports ◽  
Mucinous Cystadenoma ◽  
Clinical Importance ◽  
Benign Tumors ◽  
Review Of The Literature ◽  
Substantial Evidence ◽  
Current Case ◽  
Mucinous Neoplasms ◽  
Mucinous Epithelium ◽  
Mucinous Cystadenomas

Abstract A mucinous cystadenoma of the paratestis arising from an unequivocal oviduct-like structure in an 18-year-old man is reported. Mucinous cystadenomas of the testis and paratestis are extremely rare benign tumors of controversial origin. The diagnosis may be challenging and is of clinical importance because these lesions may mimic a teratoma, and teratomas in postpubertal males carry a malignant potential regardless of the degree of maturation. A few case reports and reviews of testicular and paratesticular mucinous neoplasms resembling ovarian tumors have suggested the possibility of a müllerian origin of these tumors. However, no histologic evidence has been found to support such a histogenesis. The current case demonstrates a clear transition from müllerian-type tubal epithelium to intestinal-type mucinous epithelium. This finding, in conjunction with immunophenotypic studies, strongly supports a derivation from a paratesticular müllerian remnant. To our knowledge this represents the first substantial evidence that, in at least some cases, mucinous cystadenomas of the testis and paratestis are of müllerian derivation.

Sign in / Sign up

Export Citation Format

Share Document