Qualitative Assessment of Diffusion Weighted Imaging and Susceptibility Weighted Imaging of Myeloid Sarcoma Involving the Brain

Abstract BACKGROUND The potential morbidity of cerebral ischemia after carotid endarterectomy (CEA) has been recognized, but its reported incidence varies widely. OBJECTIVE To prospectively evaluate the development of cerebral ischemic complications in patients treated by CEA at a high-volume cerebrovascular center. METHODS Fifty patients with moderate or severe carotid stenosis awaiting CEA were studied with perioperative diffusion-weighted imaging of the brain and standardized neurological evaluations. Microsurgical CEA was performed by 1 of 2 vascular neurosurgeons. Radiological studies were evaluated by faculty neuroradiologists who were blinded to the details of the clinical situation. RESULTS Preoperative diffusion-weighted imaging studies were performed within 24 hours of surgery. A second study was obtained within 24 (92% of patients), 48 (4% of patients), or 72 (4% of patients) hours after surgery. Intraluminal shunting was used in 1 patient (2%), and patch angioplasty was used in 2 patients (4%). No patient had diffusion-weighted imaging evidence of procedure-related cerebral ischemia. Nonischemic complications consisted of postoperative confusion in an 87-year-old man with a urinary tract infection and a marginal mandibular nerve paresis in another patient. Radiological studies were normal in both patients. CONCLUSION CEA is a relatively safe procedure that may be performed with an acceptable risk of cerebral ischemia in select patients. The low rate of ischemic complications associated with CEA sets a standard to which other carotid revascularization techniques should be held. The current results are presented with a discussion of the senior author's preferred surgical technique and a brief review of the literature.

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Imaging of the brain, including diffusion-weighted imaging in methylmalonic acidemia

Pediatric Radiology ◽

10.1007/s00247-004-1155-2 ◽

2004 ◽

Vol 34 (7) ◽

pp. 580-582 ◽

Cited By ~ 31

Author(s):

Steven J. Michel ◽

Curtis A. Given ◽

William C. Robertson

Keyword(s):

Diffusion Weighted Imaging ◽

Methylmalonic Acidemia ◽

Diffusion Weighted ◽

The Brain

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Susceptibility Weighted Imaging in Acute Stroke with Co-morbids: Magnetic Resonance Imaging Protocol Revisited

Journal of Advances in Medicine and Medical Research ◽

10.9734/jammr/2019/v29i1030134 ◽

2019 ◽

pp. 1-8 ◽

Cited By ~ 1

Author(s):

Fatima Mubarak ◽

Muhammad Danish Barakzai

Keyword(s):

Signal Intensity ◽

Diffusion Weighted Imaging ◽

Surrogate Marker ◽

Rank Correlation ◽

Acute Stage ◽

High Signal ◽

Susceptibility Weighted Imaging ◽

Imaging Protocol ◽

Diffusion Weighted ◽

Acute Infarct

Introduction: We aim to investigate ischemic penumbra using Diffusion weighted imaging- Susceptibility weighted imaging mismatch using DWI Alberta Stroke Program Early Computed tomography Stroke Score scoring in patients with multiple co morbid. Methods: From January 2011 to December, 2017; 70 consecutive patients (50 men, 20 women; mean age 64.5; range 45-82 years) with acute infarct on Diffusion weighted imaging (DWI) were selected for the study. Stroke protocol performed including DWI and susceptibility weighted imaging (SWI) on first day and repeat within three days. All initial MR images were interpreted by one Neuroradiologist with more than ten years blind to the clinical findings of each patient. The definition of an acute infarct area was high signal intensity on DWI with dark signal intensity on Apparent diffusion weighted imaging (ADC). The infarct extent was scored using the Alberta Stroke Program Early CT Score (ASPECTS) system. Infarct growth was defined as any new or larger lesion on the second DWI. For correlation with infarct growth, the same topographic system was used to record the extent of the Prominent vessel sign (PVS) on SWI. Spearman’s rank correlation test was used to examine the correlations between PVS score and infarct growth score. Regression was computed, with P<0.05 considered significant. Results: The study included 12 women and 10 men, (mean age 67.1 years). MRI images were initially acquired as stroke protocol (mean 12 hours) in acute stage and the next MRI was done within 3 days after the acute stage. 9 patients had right sided and 13 patients had left sided MCA territory infarct, the mean DWI-ASPECTS score was 4.3 (range 0–9). PVS was detected in 15 patients (mean score 4.1, range 0–10). Out of 22 patients 9 patients showed no evolution in infarct however in 13 patients evolution was from (ASPECTS mean score 3.95, range 0–9; mean infarct growth score 7.4, range 0–10). 7 patients devoid of PVS in initial MRI, did not exhibited evolution of infarction. Of 15 patients with PVS on initial MRI, 13 (87%) had infarct growth. Correlation between the evolution in infarct size and PVS score was observed (r = 0.86, P<0.001). Conclusion: PVS seen in infarcted territory is related to poor prognosis and this can be reliably used as a surrogate marker of oxygen extraction in penumbra. SWI can predict tissue at risk and can be a replacement for perfusion scan in clinical scenerio of acute ischaemic infarct.

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