Imaging of the brain, including diffusion-weighted imaging in methylmalonic acidemia

2004 ◽  
Vol 34 (7) ◽  
pp. 580-582 ◽  
Author(s):  
Steven J. Michel ◽  
Curtis A. Given ◽  
William C. Robertson
2005 ◽  
Vol 46 (1) ◽  
pp. 101-103 ◽  
Author(s):  
A. Yeşildağ ◽  
A. Ayata ◽  
B. Baykal ◽  
M. Koroglu ◽  
H. Yıldız ◽  
...  

Methylmalonic acidemia (MMA) is an inborn disorder of amino acid metabolism, often presenting with neurological symptoms. We present the results of magnetic resonance imaging (MRI) and diffusion‐weighted imaging (DWI) of the brain in a 16‐month‐old male patient with classic neurological and laboratory findings for MMA. MRI demonstrated the hyperintensity within globi pallidi both on T2‐weighted image and DWI during the acute episode of metabolic acidosis.


PEDIATRICS ◽  
2003 ◽  
Vol 112 (1) ◽  
pp. 1-7 ◽  
Author(s):  
S. J. Counsell ◽  
J. M. Allsop ◽  
M. C. Harrison ◽  
D. J. Larkman ◽  
N. L. Kennea ◽  
...  

2002 ◽  
Vol 44 (11) ◽  
pp. 907-911 ◽  
Author(s):  
Morita N. ◽  
Harada M. ◽  
Yoneda K. ◽  
Nishitani H. ◽  
Uno M.

Neurosurgery ◽  
2010 ◽  
Vol 67 (2) ◽  
pp. 286-294 ◽  
Author(s):  
Matthew O. Hebb ◽  
Joseph E. Heiserman ◽  
Kirsten P. N. Forbes ◽  
Joseph M. Zabramski ◽  
Robert F. Spetzler

Abstract BACKGROUND The potential morbidity of cerebral ischemia after carotid endarterectomy (CEA) has been recognized, but its reported incidence varies widely. OBJECTIVE To prospectively evaluate the development of cerebral ischemic complications in patients treated by CEA at a high-volume cerebrovascular center. METHODS Fifty patients with moderate or severe carotid stenosis awaiting CEA were studied with perioperative diffusion-weighted imaging of the brain and standardized neurological evaluations. Microsurgical CEA was performed by 1 of 2 vascular neurosurgeons. Radiological studies were evaluated by faculty neuroradiologists who were blinded to the details of the clinical situation. RESULTS Preoperative diffusion-weighted imaging studies were performed within 24 hours of surgery. A second study was obtained within 24 (92% of patients), 48 (4% of patients), or 72 (4% of patients) hours after surgery. Intraluminal shunting was used in 1 patient (2%), and patch angioplasty was used in 2 patients (4%). No patient had diffusion-weighted imaging evidence of procedure-related cerebral ischemia. Nonischemic complications consisted of postoperative confusion in an 87-year-old man with a urinary tract infection and a marginal mandibular nerve paresis in another patient. Radiological studies were normal in both patients. CONCLUSION CEA is a relatively safe procedure that may be performed with an acceptable risk of cerebral ischemia in select patients. The low rate of ischemic complications associated with CEA sets a standard to which other carotid revascularization techniques should be held. The current results are presented with a discussion of the senior author's preferred surgical technique and a brief review of the literature.


2010 ◽  
Vol 28 (10) ◽  
pp. 1541-1545 ◽  
Author(s):  
Cornelius von Morze ◽  
Douglas A.C. Kelley ◽  
Timothy M. Shepherd ◽  
Suchandrima Banerjee ◽  
Duan Xu ◽  
...  

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