Factors Associated with Erosive Arthritis in Rheumatoid Arthritis and Other Connective Tissue Diseases

2016 ◽  
Vol 22 (1) ◽  
pp. 22-29
Author(s):  
Shiwen Yuan ◽  
Dongying Chen ◽  
Youjun Xiao ◽  
Minxi Lao ◽  
Qian Qiu ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Connective Tissue ◽  
Connective Tissue Diseases ◽  
Factors Associated ◽  
Erosive Arthritis

Connective tissue disease

2019 ◽  
pp. 281-326
Author(s):  
Gavin Spickett
Keyword(s):  
Rheumatoid Arthritis ◽  
Connective Tissue ◽  
Connective Tissue Disease ◽  
Mixed Connective Tissue Disease ◽  
Raynaud’S Phenomenon ◽  
Connective Tissue Diseases ◽  
Raynaud's Phenomenon ◽  
Overlap Syndromes

This chapter covers the presentation, immunogenetics, immunopathology, diagnosis, treatment, and testing for a range of connective tissue diseases. It covers a range of rheumatic disorders, from rheumatoid arthritis to Raynaud’s phenomenon, and also covers the undifferentiated diseases, overlap syndromes, and mixed connective tissue disease.

Rheumatology

2014 ◽  
Author(s):  
Murray Longmore ◽  
Ian B. Wilkinson ◽  
Andrew Baldwin ◽  
Elizabeth Wallin
Keyword(s):  
Rheumatoid Arthritis ◽  
Back Pain ◽  
Ankylosing Spondylitis ◽  
Connective Tissue ◽  
Septic Arthritis ◽  
Reactive Arthritis ◽  
Mixed Connective Tissue Disease ◽  
Connective Tissue Diseases ◽  
Locomotor System ◽  
System P

The rheumatological historyAssessing the locomotor systemRheumatological investigationsBack painOsteoarthritis (oa)Septic arthritisRheumatoid arthritis (ra)Crystal arthropathies:Goutcppd arthropathySpondyloarthritides:Ankylosing spondylitis (as)Enteropathic, psoriatic and reactive arthritisAutoimmune connective tissue diseases:Mixed connective tissue disease...

scholarly journals Genetic Factors Associated with Rheumatoid Arthritis and Systemic Vasculitis: Evaluation of a Panel of Polymorphisms

2009 ◽  
Vol 27 (5) ◽  
pp. 217-223 ◽  
Author(s):  
Elisa Menegatti ◽  
Annalisa Davit ◽  
Simona Francica ◽  
Daniela Berardi ◽  
Daniela Rossi ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Connective Tissue ◽  
Frequency Analysis ◽  
Gene Polymorphisms ◽  
Genetic Factors ◽  
Systemic Vasculitis ◽  
Connective Tissue Diseases ◽  
Study Cohort ◽  
Mixed Cryoglobulinaemia ◽  
Schonlein Purpura

Immune and inflammatory response activation is a common feature of connective tissue diseases and systemic vasculitis. The aim of our study was to evaluate the possible involvement of TNFα c.-308A > G, IL-10 c.-1082A > G, uteroglobin c.38A > G, TGFβ 1 c.869C > T and NFκB2 c.-1837T > C gene polymorphisms in susceptibility to connective tissue diseases. Our study cohort included 68 unrelated patients affected by rheumatoid arthritis (RA) (37 patients) and ANCA-positive [micropolyangiitis (mPA) 17 patients] or ANCA-negative systemic vasculitis [including 8 patients with Henoch-Schönlein purpura (HSP) and 6 patients with mixed cryoglobulinaemia (MC)] as well as 98 control subjects. Allele frequency analysis of uteroglobin c.38G > A polymorphism showed a significant increase in the c.38A allele in patients (p= 0.002). Genotype frequency analysis of uteroglobin and NF-κB2 gene polymorphisms in patients showed an increase in c.38GA and c.38AA genotypes in the uteroglobin gene (p=0.02) coupled with an increase in homozygous c.-1837CC in the NF-κB2 gene (p=0.02). Our data suggest that genetic variation in UG and NF-κB2 pathways could have effects in connective tissue disease susceptibility.

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