Benefits of Hybrid SPECT/CT for 111In-Oxine- and Tc-99m-Hexamethylpropylene Amine Oxime-Labeled Leukocyte Imaging

2011 ◽  
Vol 36 (7) ◽  
pp. e50-e56 ◽  
Author(s):  
Mehdi Djekidel ◽  
Richard K. J. Brown ◽  
Morand Piert
1988 ◽  
Vol 27 (03) ◽  
pp. 83-86 ◽  
Author(s):  
B. Briele ◽  
F. Wolf ◽  
H. J. Biersack ◽  
F. F. Knapp ◽  
A. Hotze

A prospective study was initiated to compare the clinically proven results concerning localization/extent and activity of inflammatory bowel diseases with those of 111ln-oxine leukocyte imaging. All patients studied were completely examined with barium enema x-ray, clinical and laboratory investigations, and endoscopy with histopathology. A total of 31 leukocyte scans were performed in 15 patients (12 with Crohn’s disease, 3 with ulcerative colitis). The scans were graded by comparing the cell uptake of a lesion (when present) and a bone marrow area providing a count ratio (CR). The inflammatory lesions were correctly localized on 26 leukocyte scans, and in 21 scans the scintigraphically estimated extent of disease was identical to endoscopy. In 5 cases the disease extent was underestimated, 4 scans in patients with relapse of Crohn’s disease were falsely negative, and in one patient with remission truly negative. The scintigraphically assessed disease activity was also in a good agreement with clinical disease activity based on histopathology in all cases. We conclude that leukocyte imaging provides valuable information about localization and activity of inflammatory bowel disease.


Respiration ◽  
2002 ◽  
Vol 69 (2) ◽  
pp. 143-147 ◽  
Author(s):  
C.-M. Shih ◽  
Y.-C. Shiau ◽  
J.J. Wang ◽  
S.-T. Ho ◽  
A. Kao

1991 ◽  
Vol 16 (2) ◽  
pp. 103-106 ◽  
Author(s):  
BRIAN EISENBERG ◽  
JOHN E. POWE ◽  
ABASS ALAVI

1995 ◽  
Vol 22 (12) ◽  
pp. 1453-1456 ◽  
Author(s):  
Adil M. AL-Nahhas ◽  
Pantelis Hjiyiannakis ◽  
Peter A. G. Hammersley ◽  
V. Ralph McCready ◽  
Alan H. Horwich

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