Biomarker-guided Intervention to Prevent AKI or KDIGO Care Bundle to Prevent AKI in High-risk Patients Undergoing Major Surgery?

2018 ◽  
Vol 268 (6) ◽  
pp. e67-e68 ◽  
Author(s):  
Anand Narayan Singh ◽  
Ragini Kilambi
Critical Care ◽  
2007 ◽  
Vol 11 (Suppl 2) ◽  
pp. P305
Author(s):  
S Lobo ◽  
N Oliveira ◽  
F Lobo ◽  
E Rezende ◽  
B Borges ◽  
...  

2018 ◽  
Vol 7 (1) ◽  
Author(s):  
Sophie V. Griffiths ◽  
◽  
Daniel H. Conway ◽  
Michael Sander ◽  
Ib Jammer ◽  
...  

2018 ◽  
Vol 100 (6) ◽  
pp. e154-e157 ◽  
Author(s):  
K Divani ◽  
S Selvadurai ◽  
S Molloy

Long-construct fixations can be complicated by proximal junctional kyphosis. In elderly, high-risk patients with numerous comorbidities, lengthy surgical times and increased blood loss associated with revision osteotomies and extension of fusions are not often tolerated and pose serious life-threatening risks. We present a salvage technique used in a patient with proximal junctional failure and demonstrate its role in improving symptoms and functionality in those not deemed fit for major surgery. Pre- and postoperative pain scores in accordance with the visual analogue scale, walking distances and radiographs were reviewed in a patient who underwent the salvage technique to ascertain the subjective and objective difference in pain and functionality. The patient showed marked improvement in pain scores and walking distances postoperatively. Additionally, the degree of proximal junctional kyphosis was lower on postoperative radiographs. While holding risks of its own, our described technique can be performed in select cases and is a good salvage procedure in high-risk patients. It prevents their exposure to the risks that accompany large revision operations and fusion models with further potential to fail. We recommend that our technique is performed only at specialist centres.


2010 ◽  
Vol 20 (5) ◽  
pp. 173-176 ◽  
Author(s):  
Shirley Collier

This article reviews the benefits of pre-assessment with cardio-pulmonary exercise testing (CPX) and the effectiveness of preoperative interventions in high-risk patients undergoing major surgery. Three patient case studies will be presented from local practice, to give examples of how patients' co-morbidity has been improved prior to surgery or how decisions for surgery can be modified as a result of the CPX test.


This case focuses on the effectiveness of using an epidural in high-risk patients undergoing surgery by asking the question: Do intraoperative epidural anesthesia and postoperative analgesia in high-risk patients presenting for major surgery decrease adverse outcomes compared with alternative analgesic regimens? This multicenter, randomized trial demonstrated improved pain control and a reduction in postoperative respiratory complications with the use of an epidural for intraoperative anesthesia and postoperative analgesia in high-risk patients undergoing major surgery. A significant effect on overall complications or mortality was not demonstrated.


JAMA ◽  
2017 ◽  
Vol 318 (14) ◽  
pp. 1346 ◽  
Author(s):  
Emmanuel Futier ◽  
Jean-Yves Lefrant ◽  
Pierre-Gregoire Guinot ◽  
Thomas Godet ◽  
Emmanuel Lorne ◽  
...  

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