Use of the clinical pulmonary infection score to guide therapy for ventilator-associated pneumonia risks antibiotic overexposure in patients with trauma

2012 ◽  
Vol 73 (1) ◽  
pp. 52-59 ◽  
Author(s):  
Nancy A. Parks ◽  
Louis J. Magnotti ◽  
Jordan A. Weinberg ◽  
Ben L. Zarzaur ◽  
Thomas J. Schroeppel ◽  
...  
2005 ◽  
Vol 14 (4) ◽  
pp. 325-332 ◽  
Author(s):  
Mary Jo Grap ◽  
Cindy L. Munro ◽  
Russell S. Hummel ◽  
R.K. Elswick ◽  
Jessica L. McKinney ◽  
...  

• Background Ventilator-associated pneumonia is a common complication of mechanical ventilation. Backrest position and time spent supine are critical risk factors for aspiration, increasing the risk for pneumonia. Empirical evidence of the effect of backrest positions on the incidence of ventilator-associated pneumonia, especially during mechanical ventilation over time, is limited. • Objective To describe the relationship between backrest elevation and development of ventilator-associated pneumonia. • Methods A nonexperimental, longitudinal, descriptive design was used. The Clinical Pulmonary Infection Score was used to determine ventilator-associated pneumonia. Backrest elevation was measured continuously with a transducer system. Data were obtained from laboratory results and medical records from the start of mechanical ventilation up to 7 days. • Results Sixty-six subjects were monitored (276 patient days). Mean backrest elevation for the entire study period was 21.7°. Backrest elevations were less than 30° 72% of the time and less than 10° 39% of the time. The mean Clinical Pulmonary Infection Score increased but not significantly, and backrest elevation had no direct effect on mean scores. A model for predicting the Clinical Pulmonary Infection Score at day 4 included baseline score, percentage of time spent at less than 30° on study day 1, and score on the Acute Physiology and Chronic Health Evaluation II, explaining 81% of the variability (F=7.31, P=.003). • Conclusions Subjects spent the majority of the time at backrest elevations less than 30°. Only the combination of early, low backrest elevation and severity of illness affected the incidence of ventilator-associated pneumonia.


2008 ◽  
Vol 23 (1) ◽  
pp. 50-57 ◽  
Author(s):  
François Lauzier ◽  
Annie Ruest ◽  
Deborah Cook ◽  
Peter Dodek ◽  
Martin Albert ◽  
...  

2011 ◽  
Vol 48 (12) ◽  
pp. 949-954 ◽  
Author(s):  
Anil Sachdev ◽  
K. Chugh ◽  
M. Sethi ◽  
D. Gupta ◽  
C. Wattal ◽  
...  

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