Non-Melanoma Skin Cancer Incidence and Risk Factors After Kidney Transplantation: A Canadian Experience

2008 ◽  
Vol 86 (4) ◽  
pp. 535-541 ◽  
Author(s):  
Sherry Comeau ◽  
Louise Jensen ◽  
Sandra M. Cockfield ◽  
Mariusz Sapijaszko ◽  
Sita Gourishankar
2021 ◽  
Vol 160 (6) ◽  
pp. S-551
Author(s):  
Gary R. Lichtenstein ◽  
Eleni Demas ◽  
Paul Quinn ◽  
Jan-Christof Schuller ◽  
Scott D. Lee ◽  
...  

2015 ◽  
Vol 96 (3) ◽  
pp. 285-290 ◽  
Author(s):  
Montse Gómez ◽  
Vicent Guillem ◽  
Arturo Pereira ◽  
Francisca Ferrer-Marín ◽  
Alberto Álvarez-Larrán ◽  
...  

2014 ◽  
Vol 134 (1) ◽  
pp. 43-50 ◽  
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Annika Waldmann ◽  
Alan C. Geller ◽  
Martin A. Weinstock ◽  
Beate Volkmer ◽  
...  

2020 ◽  
pp. 239936932097212
Author(s):  
Davide Viggiano ◽  
Michael W Lee ◽  
Mariadelina Simeoni ◽  
Giovambattista Capasso ◽  
Anna Capasso

Kidney transplant (KT) recipients have an increased risk for specific types of cancer. Some forms of incident cancer are similarly present in other diseases where T-cells are depleted, such as HIV-infection: specifically, non-Hodgkin lymphoma and Kaposi’s sarcoma. Conversely, other forms of highly incident cancers in KT patients, primarily non-melanoma skin cancer (squamous cell carcinoma and basal cell carcinoma), are specific to this condition. By comparing HIV-related cancers, general cancer incidence, and the association of immunotherapy with cancer incidence, we suggest that the high incidence of non-melanoma skin cancer seen in KT patients is mediated by off-target effects of calcineurin inhibitors in the skin, combined with a “permissive” cancer microinflammatory environment.


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