Do preventive interventions for children of mentally ill parents work? Results of a systematic review and meta-analysis

Abstract Background There is sufficient meta-analytic evidence that antenatal interventions for women at risk (selective prevention) or for women with severe psychological symptoms (indicated prevention) are effective in reducing postpartum distress. However, women without risk or severe psychological symptoms might also experience distress. This meta-analysis focused on the effectiveness of preventive psychological interventions offered to universal populations of pregnant women on symptoms of depression, anxiety, and general stress. Paternal and infant outcomes were also included. Method We included 12 universal prevention studies in the meta-analysis, incorporating a total of 2559 pregnant women. Results Overall, ten studies included depression as an outcome measure, five studies included stress, and four studies anxiety. There was a moderate effect of preventive interventions implemented during pregnancy on the combined measure of maternal distress (d = .52), on depressive symptoms (d = .50), and on stress (d = .52). The effect on anxiety (d = .30) was smaller. The effects were not associated with intervention timing, intervention type, intervention delivery mode, timing of post-test, and methodological quality. The number of studies including partner and/or infant outcomes was too low to assess their effectiveness. Conclusions This meta-analysis suggests that universal prevention during pregnancy is effective on decreasing symptoms of maternal distress compared to routine care, at least with regard to depression. While promising, the results with regard to anxiety and stress are based on a considerably lower number of studies, and should thus be interpreted with caution. More research is needed on preventing other types of maternal distress beyond depression. Furthermore, there is a lack of research with regard to paternal distress. Also, given the large variety in interventions, more research is needed on which elements of universal prevention work. Finally, as maternal distress symptoms can affect infant development, it is important to investigate whether the positive effects of the preventive interventions extend from mother to infant. Systematic review registration number International prospective register of systematic reviews (PROSPERO) registration number: CRD42018098861.

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Comparative Efficacy of 6 Topical Pharmacological Agents for Preventive Interventions of Postoperative Sore Throat After Tracheal Intubation: A Systematic Review and Network Meta-analysis

Anesthesia & Analgesia ◽

10.1213/ane.0000000000005521 ◽

2021 ◽

Author(s):

Ge Wang ◽

Yang Qi ◽

LiNa Wu ◽

GuiChun Jiang

Keyword(s):

Systematic Review ◽

Tracheal Intubation ◽

Sore Throat ◽

Meta Analysis ◽

Preventive Interventions ◽

Comparative Efficacy ◽

Postoperative Sore Throat ◽

Pharmacological Agents

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P.0033 The effectiveness of preventive interventions for anxiety features in young people: a systematic review and meta-analysis

European Neuropsychopharmacology ◽

10.1016/j.euroneuro.2021.10.039 ◽

2021 ◽

Vol 53 ◽

pp. S24-S25

Author(s):

J.C. Moreira Pereira ◽

F. Besana ◽

L. Soardo ◽

S. Kaur ◽

A. Cabras ◽

...

Keyword(s):

Systematic Review ◽

Young People ◽

Meta Analysis ◽

Preventive Interventions

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STI Health Disparities: A Systematic Review and Meta-Analysis of the Effectiveness of Preventive Interventions in Educational Settings

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph15122819 ◽

2018 ◽

Vol 15 (12) ◽

pp. 2819 ◽

Cited By ~ 7

Author(s):

Nway Mon Kyaw Soe ◽

Yelena Bird ◽

Michael Schwandt ◽

John Moraros

Keyword(s):

Public Health ◽

Systematic Review ◽

Preventive Intervention ◽

Positive Impact ◽

Meta Analysis ◽

Motivational Factors ◽

Cochrane Library ◽

Preventive Interventions ◽

Educational Settings ◽

Transmitted Infection

The purpose of this systematic review and meta-analysis was to address disparities related to sexual health among students by examining the effectiveness of sexually transmitted infection (STI) preventive interventions in educational settings. PubMed, Medline, Cochrane Library, Public Health Database, and EMBASE databases were used to conduct searches. Information relating to studies, programs, participants, and quantitative outcome variables were extracted. Risk of bias was assessed and meta-analysis was conducted. This systematic review included 16 articles. The outcomes were classified into behavioral and psychosocial categories. The behavioral category included sexual partners, sexual activity, condom use, STI/HIV testing, and alcohol/drug use before sex. The psychosocial category consisted of knowledge, motivational factors, and skills. Interventions had a significantly positive impact on both behavioral (OR, 1.28; 95% CI, 1.17–1.39) and psychosocial (OR, 1.92; 95% CI, 1.36–2.72) outcomes. Among the psychosocial outcomes, the interventions were most effective at promoting knowledge (OR, 3.17; 95% CI, 2.13–4.72), followed by enhancing motivational factors (OR, 1.69; 95% CI, 1.04–2.75) and increasing behavioral skills (OR, 1.43; 95% CI, 1.13–1.81). The results of this systematic review provide empirical evidence for public health professionals and policy makers regarding planning, implementation, evaluation, and modification of STI preventive intervention programs in educational settings.

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Systematic review and meta-analysis of preventive interventions for eating disorders

Journal of Eating Disorders ◽

10.1186/2050-2974-3-s1-o35 ◽

2015 ◽

Vol 3 (S1) ◽

Author(s):

Long KD Le ◽

Jan Barendregt ◽

Phillipa Hay ◽

Cathrine Mihalopoulos

Keyword(s):

Systematic Review ◽

Eating Disorders ◽

Meta Analysis ◽

Preventive Interventions

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The effects of low-ratio n-6/n-3 PUFA on biomarkers of inflammation: a systematic review and meta-analysis

Food & Function ◽

10.1039/d0fo01976c ◽

2021 ◽

Author(s):

Yali Wei ◽

Yan Meng ◽

Na Li ◽

Qian Wang ◽

Liyong Chen

Keyword(s):

Systematic Review ◽

Fatty Acid ◽

Polyunsaturated Fatty Acid ◽

Meta Analysis ◽

Chain Polyunsaturated Fatty Acid ◽

Inflammation Markers ◽

Pufa Supplementation ◽

Long Chain

The purpose of the systematic review and meta-analysis was to determine if low-ratio n-6/n-3 long-chain polyunsaturated fatty acid (PUFA) supplementation affects serum inflammation markers based on current studies.

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