scholarly journals Rapid growth atypical mycobacteria infection associated with growth hormone injections: a case report

2021 ◽  
Vol 3 (11) ◽  
Author(s):  
Christian David Cardozo Lomaquiz ◽  
Tamara Frontanilla ◽  
Natalia Scavone ◽  
Alba Fretes ◽  
Nathalia Torales ◽  
...  

Introduction. Infections caused by fast growing mycobacteria have increased markedly worldwide. They are normally associated with trauma, surgery or cosmetic interventions. Paraguay has a deficit in sanitary control including clinics, private practices, and aesthetic centres. This situation is accompanied by the easy access to drugs, which leads to the performance of exclusively medical aesthetic procedures by people without professional knowledge or training. Case report. A 26-year-old female patient comes to a medical consultation with pain and bruising in the abdominal area with more than 3 months of progression, without fever or apparent cause. Later, she confessed to the application of subcutaneous injections of ‘growth hormones’ at the gym. Excisional biopsy of the lesions was carried out for anatomopathological and microbiological studies. In addition, the use of polymerase chain reaction analysis was indicated because of the strong suspicion of an atypical mycobacterial infection. The Ziehl-Neelsen staining was negative for BAAR, and the PAS-Hematoxylin negative for fungal elements. When performing the culture, the growth of atypical mycobacteria was observed on chocolate and blood agar medium culture. Through the polymerase chain reaction study, it was possible to identify the atypical mycobacterium as ‘Mycobacterium abscessus’. Conclusion. The irresponsible application of medications by people without professional authorization or biosafety precautions can lead to the development atypical infections that are difficult to diagnose and treat. This situation could lead to serious complications and even death.

2021 ◽  
Vol 55 (1) ◽  
pp. 40-44
Author(s):  
Vladimir Selaković ◽  
Milan Ranisavljević ◽  
Tijana Vasiljević ◽  
Bratislav Stoiljković ◽  
Biljana Kukić

Anorectal melanoma (AM) is an aggressive and very rare malignancy. The aim of this case report is to present a case of anorectal melanoma that occured in hemorrhoidal node after a colorectal surgery. A patient aged 69 years was treated at the Oncology Institute of Vojvodina for histopathological (HP) verified melanoma of the anorectum (S100, HMB45 and Melan A positive) localized in the hemorrhoidal node. Wide local excision was made. Three months after the operation secondary deposits ocurred at the site of the colorectal anasthomosis, stomach, lung and brain. Polymerase chain reaction analysis of tumor DNA found no mutation in the BRAF V600 gene. Five months after the operation the patient is still alive and on supportive and symptomatic therapy. Despite its rarity, AM should always be considered in unusual anorectal lesions first at all in hemorrhoid nodules.


1999 ◽  
Vol 28 (6) ◽  
pp. 1331-1332 ◽  
Author(s):  
Taru Meri ◽  
T. Sakari Jokiranta ◽  
Simo Granat ◽  
Fredrika Collander ◽  
Matti Valtonen ◽  
...  

Biomedicine ◽  
2021 ◽  
Vol 40 (4) ◽  
pp. 551-553
Author(s):  
Altynai Zhumabekova ◽  
Tugolbai Tagaev ◽  
Vityala Yethindra ◽  
Shirin Zhumabaeva ◽  
Datka Ysabaeva ◽  
...  

In December 2019, an outbreak of coronavirus disease 2019 (COVID-19) occurred in Wuhan, China. The disease, which is now a global pandemic, is reportedly associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this study, we report a case of COVID-19 in a 31-year-old pregnant woman who showed symptoms that included fever, a four-day history of dry cough, and myalgia. Real-time reverse transcriptase-polymerase chain reaction analysis of naso- and oropharyngeal samples was positive for the SARS-CoV-2. A cesarean section was performed during the acute phase of COVID-19; the full-term infant was isolated from his mother and underwent formula feeding. He was healthy and negative for the SARS-CoV-2. This report describes the clinical features, diagnosis, and treatment of the mother’s illness and its effects on her live-born infant.


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