scholarly journals Reversible hearing impairment: delayed complication of murine typhus or adverse reaction to azithromycin?

2010 ◽  
Vol 59 (5) ◽  
pp. 602-606 ◽  
Author(s):  
Shang-Yi Lin ◽  
Ya-Ling Wang ◽  
Hsiu-Fen Lin ◽  
Tun-Chieh Chen ◽  
Yen-Hsu Chen ◽  
...  

Delayed and reversible hearing loss occurred in a 55-year-old male patient with murine typhus infection. The patient had the initial symptoms of headache, fever and chills, followed by the occurrence of bilateral hearing loss on day 9 from fever onset. Murine typhus was diagnosed with a high IgM titre by indirect immunofluorescence assay. After treatment with azithromycin and prednisolone, the fever and other symptoms subsided gradually and bilateral hearing loss improved 3 weeks later. Though an adverse reaction to azithromycin could not be ruled out, delayed onset of hearing loss was more likely a complication of murine typhus, mainly because the hearing loss did not occur during the azithromycin usage period. Although hearing loss due to murine typhus is rare, clinicians should be alert to the existence of such a delayed complication.

2016 ◽  
Vol 370 ◽  
pp. 18-20 ◽  
Author(s):  
A. Paul ◽  
M. Mazighi ◽  
S. Lenck ◽  
D. Bresson ◽  
P. Herman ◽  
...  

2020 ◽  
pp. 026565902096996
Author(s):  
Damaris F Estrella-Castillo ◽  
Héctor Rubio-Zapata ◽  
Lizzette Gómez-de-Regil

Profound hearing loss can have serious and irreversible consequences for oral language development in children, affecting spoken and written language acquisition. Auditory-verbal therapy has been widely applied to children with hearing loss with promising results, mainly in developed countries where cochlear implants are available. An evaluation was done of auditory perception in 25 children 5 to 8 years of age, with profound hearing loss, users of 4- or 5-channel hearing aids, and enrolled in a personalized auditory-verbal therapy program. Regarding initial auditory perception skills, children performed better on the Noises and Sounds block than on the Language block. By subscales, top performance was observed for auditory analysis (Noises and Sounds) and auditory recognition (Language). A series of t-tests showed that significant improvement after Auditory-verbal therapy occurred in global scores for Noises and Sounds and for Language blocks, regardless of sex, urban or rural community origin, nuclear or extended family. The study provides evidence of deficiencies in auditory in children with profound bilateral hearing loss and how this might improve after receiving Auditory-verbal therapy. Nevertheless, the descriptive study design prevents conclusions regarding the effectiveness of the therapy. Subsequent research must take into account intrinsic and environmental factors that might play a mediating role in the benefits of Auditory-verbal therapy for auditory perception.


2013 ◽  
Vol 2013 ◽  
pp. 1-2
Author(s):  
Kirsti S. V. Lee ◽  
Niranjan Sritharan ◽  
Allan Forrest

This case report highlights an unusual case of sudden sensorineural hearing loss related to superficial siderosis (SS). Our patient had a craniotomy for medulloblastoma 23 years earlier, and this may represent a delayed complication related to this procedure. Magnetic resonance imaging (MRI) remains the key diagnostic investigation to illustrate the imaging features of superficial siderosis and exclude other pathologies. Increased awareness of progressive and sudden hearing complications caused by SS is important in the otolaryngologic community to expedite management and better counsel patients during the consent process.


2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Tom Gawliczek ◽  
Wilhelm Wimmer ◽  
Fabio Munzinger ◽  
Marco Caversaccio ◽  
Martin Kompis

Objective. To measure the audiological benefit of the Baha SoundArc, a recently introduced nonimplantable wearing option for bone conduction sound processor, and to compare it with the known softband wearing option in subjects with normal cochlear function and a purely conductive bilateral hearing loss.Methods. Both ears of 15 normal hearing subjects were occluded for the time of the measurement, yielding an average unaided threshold of 49 dB HL (0.5 – 4 kHz). Soundfield thresholds, speech understanding in quiet and in noise, and sound localization were measured in unaided conditions and with 1 or 2 Baha 5 sound processors mounted on either a softband or a SoundArc device.Results. Soundfield thresholds and speech reception thresholds were improved by 19.5 to 24.8 dB (p<.001), when compared to the unaided condition. Speech reception thresholds in noise were improved by 3.7 to 4.7 dB (p<.001). Using 2 sound processors rather than one improved speech understanding in noise for speech from the direction of the2nddevice and sound localization error by 23° to 28°. No statistically significant difference was found between the SoundArc and the softband wearing options in any of the tests.Conclusions. Bone conduction sound processor mounted on a SoundArc or on a softband resulted in considerable improvements in hearing and speech understanding in subjects with a simulated, purely conductive, and bilateral hearing loss. No significant difference between the 2 wearing options was found. Using 2 sound processors improves sound localization and speech understanding in noise in certain spatial settings.


2018 ◽  
Vol 127 (10) ◽  
pp. 731-734 ◽  
Author(s):  
Nathan D. Cass ◽  
Samuel P. Gubbels ◽  
Cory D. F. Portnuff

Objectives: The objective was to describe a unique case of sudden bilateral hearing loss, tinnitus, and vertigo presenting as the first symptoms of chronic myeloid leukemia (CML). Methods: A patient case is discussed along with a review of associated literature. Results: A patient presented with sudden onset hearing loss, tinnitus, and vertigo, and was diagnosed with CML with an initial white blood cell (WBC) count of 555 000 per microliter. The proposed etiology of otologic symptoms is hyperleukocytosis. Serial audiograms showed minimal improvement in hearing despite reduction of WBC. Conclusion: In cases of bilateral, sudden onset sensorineural hearing loss, evaluation for systemic causes of otologic symptoms, including CML, should be considered.


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