Genetic variability of hepatitis A virus
2003 ◽
Vol 84
(12)
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pp. 3191-3201
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Keyword(s):
Knowledge of the molecular biology of hepatitis A virus (HAV) has increased exponentially since its identification. HAV exploits all known mechanisms of genetic variation to ensure survival, including mutation and genetic recombination. HAV has been characterized by the emergence of different genotypes, three human antigenic variants and only one major serotype. This paper reviews the genetic variability and molecular epidemiology of HAV. Its evolutionary mechanisms are described with particular emphasis on genetic recombination and HAV mutation rate. Genotypic classification methods are also discussed.
1991 ◽
Vol 65
(4)
◽
pp. 2056-2065
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Keyword(s):
1991 ◽
Vol 163
(2)
◽
pp. 286-292
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2001 ◽
Vol 16
(5)
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pp. 519-524
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Keyword(s):
2017 ◽
Vol 65
(1)
◽
pp. 10-15
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2001 ◽
Vol 63
(2)
◽
pp. 88-95
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Keyword(s):
Keyword(s):
1990 ◽
Vol 87
(8)
◽
pp. 2867-2871
◽
1997 ◽
Vol 51
(4)
◽
pp. 273-279
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