scholarly journals Characterization of Solid Renal Masses using 64-Slice Multidetector CT Scanner

2009 ◽  
Vol 9 ◽  
pp. 441-448 ◽  
Author(s):  
Saleh S. El-Esawy ◽  
Mohamed E. Abou El-Ghar ◽  
Ghada M. Gaballa ◽  
Saly A. Zahra
Keyword(s):  
Cell Carcinoma ◽  
Clear Cell ◽  
Multidetector Ct ◽  
Left Kidney ◽  
Ct Scanner ◽  
Renal Masses ◽  
Surgical Data ◽  
Attenuation Values ◽  
Mdct Scanner

The purpose of our study was to assess the role of a 64-slice multidetector CT (MDCT) scanner in the characterization of different solid renal masses, using a simplified approach to correct the postenhancement attenuation values. The study included 96 consecutive adults (58 men, 38 women) with renal masses; 93 with unilateral and three with bilateral masses. All of our patients underwent multiphasic CT study including pre- and postcontrast corticomedullary (CM) and nephrographic phases. We analyzed the images and corrected the postcontrast attenuation values at the CM phase. The postbiopsy or -surgical data were used as reference standard. There were 53 masses at the right kidney, 40 at the left kidney, and three bilateral. The final diagnosis of the 96 solid parenchymal masses were 28 clear-type renal cell carcinoma (RCC), 22 papillary-type RCC, 21 chromophobe-type RCC, six XP 11.2 chromosomal translocation–type RCC, 15 angiomyolipoma (AML), and seven oncocytoma. All the AML had fat, with attenuation values less than -40 HU at the nonenhanced scan. There is no difference in the precontrast attenuation values for the different types other than AML. At the postcontrast CM phase after the correction of the attenuation values, the clear cell type could be separated easily, with attenuation values >20 with specificity, sensitivity, and overall accuracy of 92, 84, and 93%, respectively. The 64-slice MDCT scanner with application of enhancement values correction allows diagnosis of clear cell carcinoma. Also, AML could be identified easily with fat inside at the precontrast scan.

scholarly journals Two Cases of Sporadic Eosinophilic Solid and Cystic Renal Cell Carcinoma in Manitoba Population

2021 ◽  
pp. 106689692199322
Author(s):  
Seyed Mohammad Mohaghegh Poor ◽  
Shivani Mathur ◽  
Karl Kassier ◽  
Janetta Rossouw ◽  
Robert Wightman ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Clear Cell ◽  
Preoperative Imaging ◽  
Renal Neoplasm ◽  
Renal Masses ◽  
Cystic Renal Cell Carcinoma ◽  
Eosinophilic Cytoplasm ◽  
Clear Cell Rcc

Two sporadic cases of eosinophilic solid and cystic renal cell carcinoma (ESC RCC), at our institution, are presented in this study to contribute to the growing literature on this novel renal neoplasm. The first patient was a 38-year-old female with two synchronous renal masses measuring 3.5 and 1.9 cm on preoperative imaging. The second patient was a 44-year-old female with an incidental renal mass measuring 4 cm. Both patients underwent uncomplicated radical nephrectomies. The 1.9 cm mass in the first patient was consistent with clear cell RCC. The dominant mass in the first patient and the tumor in the second patient had microscopic and macroscopic findings in keeping with ESC RCC including a tan appearance, abundant eosinophilic cytoplasm, and CK20+ and CK7− staining. Both patients had an uncomplicated course following surgery with no evidence of local recurrence or distant metastatic disease for 1 and 2 years for the first and second patient accordingly. These cases contribute to a growing body of literature regarding ESC RCC including, to our knowledge, the first reported case of synchronous ESC RCC and clear cell RCC. Further research about this novel renal neoplasm is needed.

Molecular characterization of clear cell renal cell carcinoma identifies CSNK2A1, SPP1 and DEFB1 as promising novel prognostic markers

Apmis ◽  
2016 ◽  
Vol 124 (5) ◽  
pp. 372-383 ◽  
Author(s):  
Maj Rabjerg ◽  
Henriette Bjerregaard ◽  
Ulrich Halekoh ◽  
Boye L. Jensen ◽  
Steen Walter ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Molecular Characterization ◽  
Renal Cell ◽  
Prognostic Markers ◽  
Clear Cell ◽  
Cell Renal Cell Carcinoma

scholarly journals MP39-01 CHARACTERIZING RECURRENT AND LETHAL SMALL RENAL MASSES IN CLEAR CELL RENAL CELL CARCINOMA USING SOMATIC MUTATIONS

2017 ◽  
Vol 197 (4S) ◽  
Author(s):  
Brandon Manley ◽  
Ed Reznik ◽  
Maria Becerra ◽  
Jozefina Casuscelli ◽  
Daniel Tennenbaum ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Somatic Mutations ◽  
Clear Cell ◽  
Small Renal Masses ◽  
Cell Renal Cell Carcinoma ◽  
Renal Masses

scholarly journals Primitive neuroectodermal tumour with synchronous ipsilateral clear cell carcinoma of the kidney

2018 ◽  
Vol 11 (1) ◽  
pp. e224273
Author(s):  
Mohamed Taha ◽  
Nur M Mohammed ◽  
Stephen Crowther ◽  
Rustom P Manecksha ◽  
Arun Z Thomas
Keyword(s):  
Cell Carcinoma ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Left Kidney ◽  
Disease Recurrence ◽  
Cell Renal Cell Carcinoma ◽  
Primitive Neuroectodermal Tumour ◽  
Neuroectodermal Tumour ◽  
First Case ◽  
Solid Lesions

We report the first case of a synchronous ipsilateral primitive neuroectodermal tumour (PNET) and clear cell renal cell carcinoma of the kidney. A 37-year-old man presented to the emergency department with a 24-hour history of colicky abdominal pain and visible haematuria. He had no relevant surgical or medical history. Physical examination was unremarkable apart from mild left flank tenderness. Triphasic CT of the abdomen and pelvis showed two solid lesions in the left kidney. Further staging CT of the chest showed no evidence of local or distal metastasis. He subsequently underwent laparoscopic radical nephrectomy. Pathological analysis of the kidney showed two synchronous renal tumours, a clear cell carcinoma and PNET of the kidney. The patient received adjuvant chemotherapy according to Ewing’s sarcoma chemotherapy protocol. Surveillance CT scans at 3, 6 and 12 months showed no evidence of disease recurrence or metastasis.

scholarly journals MP19-04 CT-BASED VOLUMETRIC CHARACTERIZATION OF RENAL CLEAR CELL CARCINOMA IN VON HIPPEL-LINDAU (VHL) USING NOVEL HISTOGRAM ANALYSIS.

2016 ◽  
Vol 195 (4S) ◽  
Author(s):  
Ashkan Malayeri ◽  
Amir Pourmorteza ◽  
Nikeith Shah ◽  
Rabindra Gautam ◽  
Alireza Yazdi ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Renal Clear Cell Carcinoma ◽  
Histogram Analysis ◽  
Von Hippel Lindau

Establishment and characterization of a new human cell line derived from ovarian clear cell carcinoma

1990 ◽  
Vol 38 (1) ◽  
pp. 37-45 ◽  
Author(s):  
W.S.Felix Wong ◽  
Y.F. Wong ◽  
Y.T.Angela Ng ◽  
P.Dolly Huang ◽  
E.C. Chew ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Cell Line ◽  
Human Cell ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Human Cell Line ◽  
Ovarian Clear Cell Carcinoma
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