scholarly journals Nanoparticles and Inflammation

2011 ◽  
Vol 11 ◽  
pp. 1300-1312 ◽  
Author(s):  
Ross Stevenson ◽  
Axel J. Hueber ◽  
Alan Hutton ◽  
Iain B. McInnes ◽  
Duncan Graham
Keyword(s):  
Inflammatory Diseases ◽  
Molecular Probes ◽  
Disease States ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Cellular Recruitment ◽  
Enhanced Raman Scattering ◽  
New Methodologies ◽  
Magnetic Resonance Imaging Mri ◽  
New Generation

The development of nanoscale molecular probes capable of diagnosis, characterization, and clinical treatment of disease is leading to a new generation of imaging technologies. Such probes are particularly relevant to inflammation, where the detection of subclinical, early disease states could facilitate speedier detection that could yield enhanced, tailored therapies. Nanoparticles offer robust platforms capable of sensitive detection, and early research has indicated their suitability for the detection of vascular activation and cellular recruitment at subclinical levels. This suggests that nanoparticle techniques may provide excellent biomarkers for the diagnosis and progression of inflammatory diseases with magnetic resonance imaging (MRI), fluorescent quantum dots (QDs), and surface enhanced Raman scattering (SERS) probes being just some of the new methodologies employed. Development of these techniques could lead to a range of sensitive probes capable of ultrasensitive, localized detection of inflammation. This article will discuss the merits of each approach, with a general overview to their applicability in inflammatory diseases.

scholarly journals Ag Nanoparticle-Decorated Cu2S Nanosheets for Surface Enhanced Raman Spectroscopy Detection and Photocatalytic Applications

Nanomaterials ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 2508
Author(s):  
Osama Nasr ◽  
Jian-Ru Jiang ◽  
Wen-Shuo Chuang ◽  
Sheng-Wei Lee ◽  
Chih-Yen Chen
Keyword(s):  
Reduction Method ◽  
Organic Pollutant ◽  
Surface Enhanced Raman Spectroscopy ◽  
Highly Sensitive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection ◽  
Enhanced Raman Scattering ◽  
New Generation ◽  
Photocatalytic Applications

In this article, we demonstrate a facile, rapid, and practical approach to growing high-quality Cu2S nanosheets decorated with Ag nanoparticles (NPs) through the galvanic reduction method. The Ag/Cu2S nanosheets were efficiently applied to the surface-enhanced Raman scattering (SERS) and photocatalytic degradation applications. The photodegradation of RhB dye with the Ag/Cu2S nanosheets composites occurred at a rate of 2.9 times faster than that observed with the undecorated Cu2S nanosheets. Furthermore, the Ag/Cu2S nanosheets displayed highly sensitive SERS detection of organic pollutant (R6G) as low as 10−9 M. The reproducibility experiments indicated that the Ag/Cu2S nanosheets composites could be used for dual functionality in a new generation of outstandingly sensitive SERS probes for detection and stable photocatalysts.

scholarly journals Sensitive Aptamer SERS and RRS Assays for Trace Oxytetracycline Based on the Catalytic Amplification of CuNCs

Nanomaterials ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 2501
Author(s):  
Shuxin Chen ◽  
Xiaowen Lv ◽  
Jifan Shen ◽  
Siqi Pan ◽  
Zhiliang Jiang ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
Rayleigh Scattering ◽  
Molecular Probes ◽  
Resonance Rayleigh Scattering ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Wet Chemical ◽  
Amplification Reaction

A new method for the determination of oxytetracycline (OTC) has been established by coupling the catalytic amplification reaction of copper nanoclusters (CuNCs) with the aptamer reaction. CuNCs prepared by a wet chemical method have the catalytic activity for the formation of gold nanoparticles (AuNPs) resulting from a HAuCl4-ethanol (En) reaction. The experimental results showed that OTC aptamer (Apt) can be adsorbed on the surface of CuNCs in a non-specific way, thus inhibiting its catalytic activity. When OTC was added to the solution, the OTC-Apt complex was generated by a specific reaction, which made the CuNCs desorb and restore their catalytic activity. With the increase of OTC, the recovery of the catalytic activity of CuNCs is strengthened, the reaction speed is accelerated, and the number of AuNPs is increased. The generated AuNPs exhibited surface enhanced Raman scattering (SERS) signals at 1615 cm−1 in the presence of Vitoria blue 4R (VB4R) molecular probes, and a resonance Rayleigh scattering (RRS) peak at 586 nm. There is a good linear relationship between the intensities of SERS, or RRS, and OTC concentration at the range of 37.5–300 ng/L or 37.5–225 ng/L, respectively. A new SERS and RRS assay for the determination of trace OTC based on the regulation of CuNCs catalysis was established.

Monodispersed plasmonic Prussian blue nanoparticles for zero-background SERS/MRI-guided phototherapy

Nanoscale ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 3292-3301 ◽  
Author(s):  
Wei Zhu ◽  
Meng-Yue Gao ◽  
Qing Zhu ◽  
Bin Chi ◽  
Ling-Wen Zeng ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cancer Therapeutics ◽  
Resonance Imaging ◽  
Prussian Blue Nanoparticles ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Mri Guided ◽  
Magnetic Resonance Imaging Mri ◽  
Enhanced Imaging

Surface-enhanced Raman scattering (SERS) and magnetic resonance imaging (MRI)-guided phototherapy are new breakthroughs in cancer therapeutics due to their complementary advantages, such as enhanced imaging spatial resolution and depth.

scholarly journals A Highly Sensitive SERS and RRS Coupled Di-Mode Method for CO Detection Using Nanogolds as Catalysts and Bifunctional Probes

Nanomaterials ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 450 ◽  
Author(s):  
Dongmei Yao ◽  
Guiqing Wen ◽  
Lingbo Gong ◽  
Chongning Li ◽  
Aihui Liang ◽  
...  
Keyword(s):  
Rayleigh Scattering ◽  
Molecular Probes ◽  
Resonance Rayleigh Scattering ◽  
Highly Sensitive ◽  
Surface Enhanced ◽  
Mode Method ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Co Detection

Carbon monoxide (CO) is a commonly poisonous gas. It is important to detect CO in daily life. Herein, a new and sensitive surface enhanced Raman scattering (SERS) and resonance Rayleigh scattering (RRS) coupled di-mode method was developed for CO, based on gold nano-enzyme catalysis and gold nanoprobes. CO can react with HAuCl4 to generate gold nanoparticles (AuNPs) in pH 5.2 HAc-NaAc buffer. The generated AuNPs exhibited SERS activity at 1620 cm−1 in the presence of Vitoria blue B (VBB) molecular probes, and an RRS peak at 290 nm. Based on the AuNP bifunctional probes, the increased SERS and RRS intensities respond linearly with the concentration of CO in the range of 100–1500 ng/mL and 30–5230 ng/mL, respectively. To improve the sensitivity, the produced AuNPs were used as nano-enzyme catalysts for the new indicator reaction of HAuCl4-ethanol (En) to amplify the signal. The sensitive SERS method was coupled with the accurate RRS method to develop a sensitive and accurate SERS/RRS di-mode method for determination of 3.0–413 ng/mL CO, based on the AuNP-HAuCl4-En nanocatalytic reaction and its product of AuNPs as SERS and RRS bifunctional probes.

scholarly journals A comprehensive review on plasmonic-based biosensors used in viral diagnostics

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Anand M. Shrivastav ◽  
Uroš Cvelbar ◽  
Ibrahim Abdulhalim
Keyword(s):  
Virus Detection ◽  
Infrared Absorption Spectroscopy ◽  
Enhanced Fluorescence ◽  
Surface Enhanced Fluorescence ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Available Information ◽  
New Generation ◽  
Viral Diagnostics

AbstractThe proliferation and transmission of viruses has become a threat to worldwide biosecurity, as exemplified by the current COVID-19 pandemic. Early diagnosis of viral infection and disease control have always been critical. Virus detection can be achieved based on various plasmonic phenomena, including propagating surface plasmon resonance (SPR), localized SPR, surface-enhanced Raman scattering, surface-enhanced fluorescence and surface-enhanced infrared absorption spectroscopy. The present review covers all available information on plasmonic-based virus detection, and collected data on these sensors based on several parameters. These data will assist the audience in advancing research and development of a new generation of versatile virus biosensors.

scholarly journals Raman reporters derived from aryl diazonium salts for SERS encoded-nanoparticles

2020 ◽  
Vol 56 (50) ◽  
pp. 6822-6825
Author(s):  
Yun Luo ◽  
Yu Xiao ◽  
Delphine Onidas ◽  
Laura Iannazzo ◽  
Mélanie Ethève-Quelquejeu ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Raman Scattering ◽  
Diazonium Salt ◽  
Diazonium Salts ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Aryl Diazonium Salt ◽  
Diazonium Salt Chemistry ◽  
New Generation

A new generation of surface-enhanced Raman scattering encoded-nanoparticles has been designed by combining aryl diazonium salt chemistry and gold nanoparticles.

Sign in / Sign up

Export Citation Format

Share Document