scholarly journals Arousal dependent modulation of thalamo-cortical functional interaction

2017 ◽  
Author(s):  
Iain Stitt ◽  
Zhe Charles Zhou ◽  
Susanne Radtke-Schuller ◽  
Flavio Fröhlich
Keyword(s):  
Visual Processing ◽  
Posterior Parietal Cortex ◽  
Active Vision ◽  
Saccadic Eye Movements ◽  
Dynamic Interaction ◽  
Visual Exploration ◽  
Functional Interaction ◽  
Lateral Posterior ◽  
Posterior Parietal ◽  
And Behavior

Summary paragraphCognition and behavior emerge from the dynamic interaction of widely distributed, but functionally specialized brain networks. However, it remains unclear how network-level interactions dynamically reorganize to support ever-shifting cognitive and behavioral demands. Here, we investigate how the interaction between posterior parietal cortex (PPC) and lateral posterior (LP) / Pulvinar is shaped by ongoing fluctuations in pupil-linked arousal, which is a non-invasive measure related to neuromodulatory tone in the brain. We found that fluctuations in pupil-linked arousal tracked the dynamic interaction between PPC and LP/Pulvinar characterized by changes in the direction and carrier frequency of oscillatory interaction. Active visual exploration by saccadic eye movements elicited similar transitions in thalamo-cortical interaction. These findings suggest a common network substrate of both spontaneous activity and active vision. Thus, neuromodulators may play a role in dynamically sculpting the patterns of thalamo-cortical functional interaction that underlie visual processing.

Comparison of subcortical connections of inferior temporal and posterior parietal cortex in monkeys

1993 ◽  
Vol 10 (1) ◽  
pp. 59-72 ◽  
Author(s):  
Joan S. Baizer ◽  
Robert Desimone ◽  
Leslie G. Ungerleider
Keyword(s):  
Parietal Cortex ◽  
Visual Processing ◽  
Posterior Parietal Cortex ◽  
Temporal Cortex ◽  
Spatial Vision ◽  
Nucleus Basalis ◽  
Basal Nuclei ◽  
Processing Pathways ◽  
Posterior Parietal ◽  
Area Te

AbstractTo investigate the subcortical connections of the object vision and spatial vision cortical processing pathways, we injected the inferior temporal and posterior parietal cortex of six Rhesus monkeys with retrograde or anterograde tracers. The temporal injections included area TE on the lateral surface of the hemisphere and adjacent portions of area TEO. The parietal injections covered the posterior bank of the intraparietal sulcus, including areas VIP and LIP. Our results indicate that several structures project to both the temporal and parietal cortex, including the medial and lateral pulvinar, claustrum, and nucleus basalis. However, the cells in both the pulvinar and claustrum that project to the two systems are mainly located in different parts of those structures, as are the terminals which arise from the temporal and parietal cortex. Likewise, the projections from the temporal and parietal cortex to the caudate nucleus and putamen are largely segregated. Finally, we found projections to the pons and superior colliculus from parietal but not temporal cortex, whereas we found the lateral basal and medial basal nuclei of the amygdala to be reciprocally connected with temporal but not parietal cortex. Thus, the results show that, like the cortical connections of the two visual processing systems, the subcortical connections are remarkably segregated.

scholarly journals Human posterior parietal cortex responds to visual stimuli as early as peristriate occipital cortex

2018 ◽  
Author(s):  
Tamar I. Regev ◽  
Jonathan Winawer ◽  
Edden M. Gerber ◽  
Robert T. Knight ◽  
Leon Y. Deouell
Keyword(s):  
Visual Processing ◽  
Posterior Parietal Cortex ◽  
Right Hemisphere ◽  
Intractable Epilepsy ◽  
Event Related Potentials ◽  
Visual Responses ◽  
Baseline Activity ◽  
Visual Areas ◽  
Related Potentials ◽  
Posterior Parietal

AbstractMuch of what is known about the timing of visual processing in the brain is inferred from intracranial studies in monkeys, with human data limited to mainly non-invasive methods with lower spatial resolution. Here, we estimated visual onset latencies from electrocorticographic (ECoG) recordings in a patient who was implanted with 112 sub-dural electrodes, distributed across the posterior cortex of the right hemisphere, for pre-surgical evaluation of intractable epilepsy. Functional MRI prior to surgery was used to determine boundaries of visual areas. The patient was presented with images of objects from several categories. Event Related Potentials (ERPs) were calculated across all categories excluding targets, and statistically reliable onset latencies were determined using a bootstrapping procedure over the single trial baseline activity in individual electrodes. The distribution of onset latencies broadly reflected the known hierarchy of visual areas, with the earliest cortical responses in primary visual cortex, and higher areas showing later responses. A clear exception to this pattern was robust, statistically reliable and spatially localized, very early responses on the bank of the posterior intra-parietal sulcus (IPS). The response in the IPS started nearly simultaneously with responses detected in peristriate visual areas, around 60 milliseconds post-stimulus onset. Our results support the notion of early visual processing in the posterior parietal lobe, not respecting traditional hierarchies, and give direct evidence for the upper limit of onset times of visual responses across the human cortex.

Thalamic Inputs to Posterior Parietal Cortical Areas Involved in Skilled Forelimb Movement and Tool Use in the Capuchin Monkey

2019 ◽  
Vol 29 (12) ◽  
pp. 5098-5115
Author(s):  
Andrei Mayer ◽  
Gabriela Lewenfus ◽  
Ruben Ernesto Bittencourt-Navarrete ◽  
Francisco Clasca ◽  
João Guedes da Franca
Keyword(s):  
Functional Connectivity ◽  
Tool Use ◽  
Posterior Parietal Cortex ◽  
Capuchin Monkey ◽  
Cell Populations ◽  
Cortical Areas ◽  
Thalamic Input ◽  
Lateral Posterior ◽  
Posterior Parietal ◽  
Forelimb Movement

Abstract The posterior parietal cortex (PPC) is a central hub for the primate forebrain networks that control skilled manual behavior, including tool use. Here, we quantified and compared the sources of thalamic input to electrophysiologically-identified hand/forearm-related regions of several PPC areas, namely areas 5v, AIP, PFG, and PF, of the capuchin monkey (Sapajus sp). We found that these areas receive most of their thalamic connections from the Anterior Pulvinar (PuA), Lateral Posterior (LP) and Medial Pulvinar (PuM) nuclei. Each PPC area receives a specific combination of projections from these nuclei, and fewer additional projections from other nuclei. Moreover, retrograde labeling of the cells innervating different PPC areas revealed substantial intermingling of these cells within the thalamus. Differences in thalamic input may contribute to the different functional properties displayed by the PPC areas. Furthermore, the observed innervation of functionally-related PPC domains from partly intermingled thalamic cell populations accords with the notion that higher-order thalamic inputs may dynamically regulate functional connectivity between cortical areas.

A Tale of Two Visual Systems: Invariant and Adaptive Visual Information Representations in the Primate Brain

2018 ◽  
Vol 4 (1) ◽  
pp. 311-336 ◽  
Author(s):  
Yaoda Xu
Keyword(s):  
Visual Processing ◽  
Visual Information ◽  
Posterior Parietal Cortex ◽  
Visual Representations ◽  
Primate Brain ◽  
Visual Systems ◽  
Two Visual Systems ◽  
Adaptive Nature ◽  
And Behavior

Visual information processing contains two opposite needs. There is both a need to comprehend the richness of the visual world and a need to extract only pertinent visual information to guide thoughts and behavior at a given moment. I argue that these two aspects of visual processing are mediated by two complementary visual systems in the primate brain—specifically, the occipitotemporal cortex (OTC) and the posterior parietal cortex (PPC). The role of OTC in visual processing has been documented extensively by decades of neuroscience research. I review here recent evidence from human imaging and monkey neurophysiology studies to highlight the role of PPC in adaptive visual processing. I first document the diverse array of visual representations found in PPC. I then describe the adaptive nature of visual representation in PPC by contrasting visual processing in OTC and PPC and by showing that visual representations in PPC largely originate from OTC.

Eye-centered, head-centered, and intermediate coding of remembered sound locations in area LIP

1996 ◽  
Vol 76 (3) ◽  
pp. 2071-2076 ◽  
Author(s):  
B. Stricanne ◽  
R. A. Andersen ◽  
P. Mazzoni
Keyword(s):  
Visual Information ◽  
Posterior Parietal Cortex ◽  
Reference Frames ◽  
Visual Stimulation ◽  
Spatial Vision ◽  
Saccadic Eye Movements ◽  
Auditory Memory ◽  
Exact Nature ◽  
Sound Sources ◽  
Posterior Parietal

1. The lateral intraparietal area (LIP) of the posterior parietal cortex lies within the dorsal cortical stream for spatial vision and processes visual information to plan saccadic eye movements. We investigated how LIP neurons respond when a monkey makes saccades to the remembered location of sound sources in the absence of visual stimulation. 2. Forty-three (36%) of the 118 neurons sampled showed significant auditory triggered activity during the memory period. This figure is similar to the proportion of cells showing visually triggered memory activity. 3. Of the cells showing auditory memory activity, 44% discharged in an eye-centered manner, similar to the way in which LIP cells discharge for visually initiated saccades. Another 33% responded in head-centered coordinates, and the remaining 23% had responses intermediate between the two reference frames. 4. For a substantial number of cells in all three categories, the magnitude of the response was modulated by eye position. Similar orbital "gain fields" had been shown previously for visual saccades. 5. We propose that area LIP is either at the origin of, or participates in, the transformation of auditory signals for oculomotor purposes, and that orbital gains on the discharge are part of this process. 6. Finally, we suggest that, by the level of area LIP, cells are concerned with the abstract quality of where a stimulus is in space, independent of the exact nature of the stimulus.

scholarly journals When Left Is One and Right Is Double: An Experimental Investigation of Visual Allesthesia after Right Parietal Damage

Vision ◽  
2020 ◽  
Vol 4 (1) ◽  
pp. 16
Author(s):  
Denise Baumeler ◽  
Sabine Born ◽  
Nicolas Burra ◽  
Radek Ptak
Keyword(s):  
Visual Processing ◽  
Posterior Parietal Cortex ◽  
Experimental Studies ◽  
Physiological Processes ◽  
Unilateral Stimulation ◽  
Original Stimulus ◽  
Stationary Objects ◽  
Visual Phenomena ◽  
Posterior Parietal ◽  
Automatic Activation

Illusory visual phenomena, such as palinopsia, polyopsia or allesthesia, are rare manifestations of posterior cortical damage. Symptoms are characterized by illusory perceptions, ranging from isolated stationary objects to scenes and moving persons. Such illusions may appear while the original object is still in view, or become manifest with a delay and last for minutes, hours or even days. Some authors have suggested a disinhibited cortical response underlying visual illusions, but experimental studies supporting this hypothesis are lacking. Here, we examined a rare patient who after focal right parietal injury consistently reported a second stimulus on the left when briefly shown a target in his right hemifield. The patient perceived the illusory stimulus as less intense, and therefore concluded that it must have a different shape than the original stimulus. A masking experiment revealed that the frequency of the illusion was inversely related to the visibility of the original stimulus, suggesting that it depended on early, feedforward visual processing. We propose that illusory perceptions reflect the interplay of two physiological processes: a fast and automatic activation of contralateral, homotopic visual cortex after unilateral stimulation, and the lack of top-down inhibition following damage to the posterior parietal cortex.

Evidence for Anticipatory Motor Control within a Cerebello-Diencephalic-Parietal Network

2008 ◽  
Vol 20 (5) ◽  
pp. 828-840 ◽  
Author(s):  
Bettina Pollok ◽  
Joachim Gross ◽  
Daniel Kamp ◽  
Alfons Schnitzler
Keyword(s):  
Motor Control ◽  
Functional Connectivity ◽  
Internal Model ◽  
Posterior Parietal Cortex ◽  
Phase Synchronization ◽  
Functional Interaction ◽  
Feedback Processing ◽  
Spatially Distributed ◽  
Posterior Parietal ◽  
Anticipatory Motor Control

The posterior parietal cortex and the cerebellum are assumed to contribute to anticipatory motor control. Thus, it is reasonable that these areas act as a functional unit. To identify a neural signature of anticipatory motor control, 11 healthy volunteers performed a bimanual finger-tapping task with respect to isochronous (i.e., regular) and randomized (i.e., irregular) auditory pacing. Neuromagnetic activity was recorded using a 122-channel whole-head neuromagnetometer. Functional interaction between spatially distributed brain areas was determined by measures of tap-related phase synchronization. Assuming that (i) the cerebellum predicts sensory events by an internal model and (ii) the PPC maintains this prediction, we hypothesized that functional interaction between both structures varies depending on the predictability of the pacing signal. During isochronous pacing, functional connectivity within a cerebello-diencephalic-parietal network before tap onset was evident, suggesting anticipatory motor control. During randomized pacing, however, functional connectivity after tap onset was increased within a parietal-cerebellar loop, suggesting mismatch detection and update of the internal model. Data of the present study imply that anticipatory motor control is implemented in a network-like manner. Our data agree well with the hypothesis that functional connectivity in a cerebello-diencephalic-parietal loop might be crucial for anticipatory motor control, whereas parietal-cerebellar interaction might be critical for feedback processing.

Sign in / Sign up

Export Citation Format

Share Document