scholarly journals Automatic subtyping of individuals with Primary Progressive Aphasia

2020 ◽  
Author(s):  
Charalambos Themistocleous ◽  
Bronte Ficek ◽  
Kimberly Webster ◽  
Dirk-Bart den Ouden ◽  
Argye E. Hillis ◽  
...  
Keyword(s):  
Machine Learning ◽  
Classification Accuracy ◽  
Primary Progressive Aphasia ◽  
Support Vector ◽  
Progressive Aphasia ◽  
Primary Progressive ◽  
Machine Learning Model ◽  
Machine Learning Approach ◽  
Automated Machine Learning

AbstractBackgroundThe classification of patients with Primary Progressive Aphasia (PPA) into variants is time-consuming, costly, and requires combined expertise by clinical neurologists, neuropsychologists, speech pathologists, and radiologists.ObjectiveThe aim of the present study is to determine whether acoustic and linguistic variables provide accurate classification of PPA patients into one of three variants: nonfluent PPA, semantic PPA, and logopenic PPA.MethodsIn this paper, we present a machine learning model based on Deep Neural Networks (DNN) for the subtyping of patients with PPA into three main variants, using combined acoustic and linguistic information elicited automatically via acoustic and linguistic analysis. The performance of the DNN was compared to the classification accuracy of Random Forests, Support Vector Machines, and Decision Trees, as well as expert clinicians’ classifications.ResultsThe DNN model outperformed the other machine learning models with 80% classification accuracy, providing reliable subtyping of patients with PPA into variants and it even outperformed auditory classification of patients into variants by clinicians.ConclusionsWe show that the combined speech and language markers from connected speech productions provide information about symptoms and variant subtyping in PPA. The end-to-end automated machine learning approach we present can enable clinicians and researchers to provide an easy, quick and inexpensive classification of patients with PPA.

scholarly journals Automatic Subtyping of Individuals with Primary Progressive Aphasia

2021 ◽  
pp. 1-10
Author(s):  
Charalambos Themistocleous ◽  
Bronte Ficek ◽  
Kimberly Webster ◽  
Dirk-Bart den Ouden ◽  
Argye E. Hillis ◽  
...  
Keyword(s):  
Machine Learning ◽  
Classification Accuracy ◽  
Primary Progressive Aphasia ◽  
Support Vector ◽  
Progressive Aphasia ◽  
Primary Progressive ◽  
Machine Learning Model ◽  
Machine Learning Approach ◽  
Automated Machine Learning

Background: The classification of patients with primary progressive aphasia (PPA) into variants is time-consuming, costly, and requires combined expertise by clinical neurologists, neuropsychologists, speech pathologists, and radiologists. Objective: The aim of the present study is to determine whether acoustic and linguistic variables provide accurate classification of PPA patients into one of three variants: nonfluent PPA, semantic PPA, and logopenic PPA. Methods: In this paper, we present a machine learning model based on deep neural networks (DNN) for the subtyping of patients with PPA into three main variants, using combined acoustic and linguistic information elicited automatically via acoustic and linguistic analysis. The performance of the DNN was compared to the classification accuracy of Random Forests, Support Vector Machines, and Decision Trees, as well as to expert clinicians’ classifications. Results: The DNN model outperformed the other machine learning models as well as expert clinicians’ classifications with 80% classification accuracy. Importantly, 90% of patients with nfvPPA and 95% of patients with lvPPA was identified correctly, providing reliable subtyping of these patients into their corresponding PPA variants. Conclusion: We show that the combined speech and language markers from connected speech productions can inform variant subtyping in patients with PPA. The end-to-end automated machine learning approach we present can enable clinicians and researchers to provide an easy, quick, and inexpensive classification of patients with PPA.

scholarly journals Application of Machine Learning to Electroencephalography for the Diagnosis of Primary Progressive Aphasia: A Pilot Study

2021 ◽  
Vol 11 (10) ◽  
pp. 1262
Author(s):  
Carlos Moral-Rubio ◽  
Paloma Balugo ◽  
Adela Fraile-Pereda ◽  
Vanesa Pytel ◽  
Lucía Fernández-Romero ◽  
...  
Keyword(s):  
Machine Learning ◽  
Graph Theory ◽  
Resting State ◽  
Naive Bayes ◽  
Primary Progressive Aphasia ◽  
Naïve Bayes ◽  
Support Vector ◽  
Progressive Aphasia ◽  
Primary Progressive ◽  
Lower Accuracy

Background. Primary progressive aphasia (PPA) is a neurodegenerative syndrome in which diagnosis is usually challenging. Biomarkers are needed for diagnosis and monitoring. In this study, we aimed to evaluate Electroencephalography (EEG) as a biomarker for the diagnosis of PPA. Methods. We conducted a cross-sectional study with 40 PPA patients categorized as non-fluent, semantic, and logopenic variants, and 20 controls. Resting-state EEG with 32 channels was acquired and preprocessed using several procedures (quantitative EEG, wavelet transformation, autoencoders, and graph theory analysis). Seven machine learning algorithms were evaluated (Decision Tree, Elastic Net, Support Vector Machines, Random Forest, K-Nearest Neighbors, Gaussian Naive Bayes, and Multinomial Naive Bayes). Results. Diagnostic capacity to distinguish between PPA and controls was high (accuracy 75%, F1-score 83% for kNN algorithm). The most important features in the classification were derived from network analysis based on graph theory. Conversely, discrimination between PPA variants was lower (Accuracy 58% and F1-score 60% for kNN). Conclusions. The application of ML to resting-state EEG may have a role in the diagnosis of PPA, especially in the differentiation from controls. Future studies with high-density EEG should explore the capacity to distinguish between PPA variants.

The Classification of Skateboarding Tricks : A Transfer Learning and Machine Learning Approach

Mekatronika ◽  
2020 ◽  
Vol 2 (2) ◽  
pp. 1-12
Author(s):  
Muhammad Nur Aiman Shapiee ◽  
Muhammad Ar Rahim Ibrahim ◽  
Muhammad Amirul Abdullah ◽  
Rabiu Muazu Musa ◽  
Noor Azuan Abu Osman ◽  
...  
Keyword(s):  
Machine Learning ◽  
Classification Accuracy ◽  
Nearest Neighbor ◽  
Olympic Games ◽  
Learning Approach ◽  
K Nearest Neighbor ◽  
Test Dataset ◽  
Machine Learning Approach ◽  
Competitive Games

The skateboarding scene has arrived at new statures, particularly with its first appearance at the now delayed Tokyo Summer Olympic Games. Hence, attributable to the size of the game in such competitive games, progressed creative appraisal approaches have progressively increased due consideration by pertinent partners, particularly with the enthusiasm of a more goal-based assessment. This study purposes for classifying skateboarding tricks, specifically Frontside 180, Kickflip, Ollie, Nollie Front Shove-it, and Pop Shove-it over the integration of image processing, Trasnfer Learning (TL) to feature extraction enhanced with tradisional Machine Learning (ML) classifier. A male skateboarder performed five tricks every sort of trick consistently and the YI Action camera captured the movement by a range of 1.26 m. Then, the image dataset were features built and extricated by means of  three TL models, and afterward in this manner arranged to utilize by k-Nearest Neighbor (k-NN) classifier. The perception via the initial experiments showed, the MobileNet, NASNetMobile, and NASNetLarge coupled with optimized k-NN classifiers attain a classification accuracy (CA) of 95%, 92% and 90%, respectively on the test dataset. Besides, the result evident from the robustness evaluation showed the MobileNet+k-NN pipeline is more robust as it could provide a decent average CA than other pipelines. It would be demonstrated that the suggested study could characterize the skateboard tricks sufficiently and could, over the long haul, uphold judges decided for giving progressively objective-based decision.

scholarly journals Machine learning for psychiatric patient triaging: an investigation of cascading classifiers

2018 ◽  
Vol 25 (11) ◽  
pp. 1481-1487 ◽  
Author(s):  
Vivek Kumar Singh ◽  
Utkarsh Shrivastava ◽  
Lina Bouayad ◽  
Balaji Padmanabhan ◽  
Anna Ialynytchev ◽  
...  
Keyword(s):  
Machine Learning ◽  
Psychiatric Patient ◽  
Classification Accuracy ◽  
Psychiatric Patients ◽  
Patient Records ◽  
Classification Technique ◽  
Machine Learning Approach ◽  
The One ◽  
Unique Dataset

Abstract Objective Develop an approach, One-class-at-a-time, for triaging psychiatric patients using machine learning on textual patient records. Our approach aims to automate the triaging process and reduce expert effort while providing high classification reliability. Materials and Methods The One-class-at-a-time approach is a multistage cascading classification technique that achieves higher triage classification accuracy compared to traditional multiclass classifiers through 1) classifying one class at a time (or stage), and 2) identification and application of the highest accuracy classifier at each stage. The approach was evaluated using a unique dataset of 433 psychiatric patient records with a triage class label provided by “I2B2 challenge,” a recent competition in the medical informatics community. Results The One-class-at-a-time cascading classifier outperformed state-of-the-art classification techniques with overall classification accuracy of 77% among 4 classes, exceeding accuracies of existing multiclass classifiers. The approach also enabled highly accurate classification of individual classes—the severe and mild with 85% accuracy, moderate with 64% accuracy, and absent with 60% accuracy. Discussion The triaging of psychiatric cases is a challenging problem due to the lack of clear guidelines and protocols. Our work presents a machine learning approach using psychiatric records for triaging patients based on their severity condition. Conclusion The One-class-at-a-time cascading classifier can be used as a decision aid to reduce triaging effort of physicians and nurses, while providing a unique opportunity to involve experts at each stage to reduce false positive and further improve the system’s accuracy.

scholarly journals A Novel Method for Sea-Land Clutter Separation Using Regularized Randomized and Kernel Ridge Neural Networks

Sensors ◽  
2020 ◽  
Vol 20 (22) ◽  
pp. 6491
Author(s):  
Le Zhang ◽  
Jeyan Thiyagalingam ◽  
Anke Xue ◽  
Shuwen Xu
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Neural Networks ◽  
Classification Accuracy ◽  
Signal Amplitude ◽  
Statistical Characteristics ◽  
Support Vector ◽  
Amplitude Change ◽  
Novel Method

Classification of clutter, especially in the context of shore based radars, plays a crucial role in several applications. However, the task of distinguishing and classifying the sea clutter from land clutter has been historically performed using clutter models and/or coastal maps. In this paper, we propose two machine learning, particularly neural network, based approaches for sea-land clutter separation, namely the regularized randomized neural network (RRNN) and the kernel ridge regression neural network (KRR). We use a number of features, such as energy variation, discrete signal amplitude change frequency, autocorrelation performance, and other statistical characteristics of the respective clutter distributions, to improve the performance of the classification. Our evaluation based on a unique mixed dataset, which is comprised of partially synthetic clutter data for land and real clutter data from sea, offers improved classification accuracy. More specifically, the RRNN and KRR methods offer 98.50% and 98.75% accuracy, outperforming the conventional support vector machine and extreme learning based solutions.

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