scholarly journals Effectiveness of psychosocial interventions for hypertensive disorders in pregnancy: A systematic review and meta-analysis

2022 ◽  
Author(s):  
Daniel A. Nnate ◽  
Kobi Vannessa Ajayi ◽  
Md Mahbub Hossain ◽  
Paul Guerby
Keyword(s):  
Spiritual Care ◽  
Meta Analysis ◽  
Psychosocial Interventions ◽  
Behavioural Therapy ◽  
Care Education ◽  
Hypertensive Disorders ◽  
Cognitive Behavioural ◽  
Hypertensive Disorders In Pregnancy ◽  
Gestational Stress ◽  
In Pregnancy

Objective: Studies on psychosocial interventions for perinatal mental health and wellbeing are mostly limited to the postpartum period. However, the physiological changes associated with hypertensive disorders in pregnancy predisposes women to severe psychological distress and adverse birth outcomes. This review investigated the effectiveness of psychosocial interventions for hypertensive disorders during pregnancy. Methods: Cochrane CENTRAL, Embase, MEDLINE, MIDIRS, CINAHL, PsycINFO, PsycArticles, and Web of Science were searched up to 22nd August 2021. Effect sizes on relevant health outcomes were pooled in a meta‐analysis using STATA software. Results: Eight randomised trials involving 460 participants met the inclusion criteria. Included studies adopted several interventions ranging from music, exercise, cognitive behavioural therapy (CBT), spiritual care education and psychoeducation. The pooled effect showed a significant reduction in anxiety (d= −0.35 [−0.58, −0.11], p=0.004) and depression (d= −0.37 [−0.57, −0.17], p=0.0003). Spiritual care education significantly reduced postpartum stress disorder (d= −62.00 [−93.10, −30.90], p= 0.0001). However, CBT showed no effect on gestational stress (d= −2.20 [-4.89, 0.48], p= 0.11). Conclusion: This study provides satisfactory evidence that psychosocial interventions may likely reduce anxiety and depression associated with hypertensive disorders in pregnancy. However, the evidence is very uncertain about its effect on neonatal outcomes.

The correlation between PM2.5 exposure and hypertensive disorders in pregnancy: A Meta-analysis

2020 ◽  
Vol 703 ◽  
pp. 134985 ◽  
Author(s):  
Mengqi Sun ◽  
Wu Yan ◽  
Kacey Fang ◽  
Danrong Chen ◽  
Jiani Liu ◽  
...  
Keyword(s):  
Meta Analysis ◽  
Hypertensive Disorders ◽  
Hypertensive Disorders In Pregnancy ◽  
Pm2.5 Exposure ◽  
In Pregnancy

scholarly journals Nutraceuticals and Hypertensive Disorders in Pregnancy: The Available Clinical Evidence

Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 378 ◽  
Author(s):  
Silvia Fogacci ◽  
Federica Fogacci ◽  
Arrigo F.G. Cicero
Keyword(s):  
Blood Pressure ◽  
Dietary Supplements ◽  
Search Strategy ◽  
Clinical Evidence ◽  
Meta Analysis ◽  
Cochrane Collaboration ◽  
Hypertensive Disorders ◽  
Pressure Lowering ◽  
Hypertensive Disorders In Pregnancy ◽  
In Pregnancy

The aim of the present critical review is to summarize the available clinical evidence supporting the use of some dietary supplements that have been shown to lower blood pressure in hypertensive pregnant women. A systematic search strategy was carried out to identify trials in MEDLINE (National Library of Medicine, Bethesda, Maryland, MD, USA; January 1980 to September 2019) and the Cochrane Register of Controlled Trials (The Cochrane Collaboration, Oxford, UK). The terms ‘nutraceuticals’, ‘dietary supplements’, ‘pregnancy’, ‘pre-eclampsia’, ‘clinical trial’, and ‘human’ were incorporated into an electronic search strategy. The references of the identified studies and review articles were reviewed to look for additional studies of interest. We preferably selected papers that reported recent comprehensive reviews or meta-analysis, or original clinical trials of substances with blood pressure-lowering or vascular protective effect in pregnancy. There is a relative body of evidence that supports the use of calcium, vitamin D, folic acid, and resveratrol in preventing the development of hypertensive disorders in pregnancy, and evidence supporting drug treatment too. Further clinical research is advisable to identify the dosage and timing of the supplementation, the group of women that might benefit the most from this approach, and the nutraceuticals with the best cost-effectiveness and risk-benefit ratio for widespread use in clinical practice.

scholarly journals P.076 Hypertensive disorders in pregnancy are strongly associated with future stroke and hypertension: A systematic review and meta-analysis

2021 ◽  
Vol 48 (s3) ◽  
pp. S40-S41
Author(s):  
AR Switzer ◽  
EE Smith ◽  
A Ganesh
Keyword(s):  
Gestational Hypertension ◽  
Meta Analysis ◽  
Stroke Mortality ◽  
Case Control Studies ◽  
Stroke Subtype ◽  
Stroke Incidence ◽  
Hypertensive Disorders ◽  
Hazard Ratios ◽  
Hypertensive Disorders In Pregnancy ◽  
In Pregnancy

Background: We aimed to evaluate the association between hypertensive disorders in pregnancy (HDP) and future risk of stroke, stroke death, and hypertension. Methods: Systematic searches were performed in MEDLINE and EMBASE up to April 27th, 2020. Exposure of interest included the different types of HDP. Outcomes of interest included hypertension incidence, stroke incidence, stroke subtype, and stroke mortality. Results: Eighteen cohort and 1 case-control studies involving >10 million women were included in the meta-analysis. Pooled hazard ratios with 95% confidence interval generally adjusted for age at delivery, ethnicity, and vascular risk factors are listed in table 1. Conclusions: Increasing severities of HDP carry higher hazards of hypertension and stroke years later. HDP, including gestational hypertension alone, are also associated with future stroke mortality.

scholarly journals Risk of hypertensive disorders in pregnancy following assisted reproductive technology: overview and meta-analysis

2016 ◽  
Vol 19 (2) ◽  
pp. 173-183 ◽  
Author(s):  
Costas Thomopoulos ◽  
George Salamalekis ◽  
Konstantinos Kintis ◽  
Iliana Andrianopoulou ◽  
Helena Michalopoulou ◽  
...  
Keyword(s):  
Assisted Reproductive Technology ◽  
Meta Analysis ◽  
Reproductive Technology ◽  
Hypertensive Disorders ◽  
Hypertensive Disorders In Pregnancy ◽  
In Pregnancy

scholarly journals P.016 Hypertensive disorders in pregnancy are associated with future development of vascular dementia: A systematic review and meta-analysis

2021 ◽  
Vol 48 (s3) ◽  
pp. S24-S24
Author(s):  
A Switzer ◽  
EE Smith ◽  
A Ganesh
Keyword(s):  
Vascular Dementia ◽  
Meta Analysis ◽  
Alzheimer Dementia ◽  
Motor Processing ◽  
Hypertensive Disorders ◽  
Hypertensive Disorders In Pregnancy ◽  
History Of ◽  
Visual Motor ◽  
Visual Motor Processing ◽  
In Pregnancy

Background: We aimed to evaluate the association between hypertensive disorders in pregnancy (HDP) and future risk of cognitive impairment and dementia. Methods: Systematic searches were performed in MEDLINE and EMBASE up to April 27th, 2020. Exposure of interest included the different types of HDP. Outcomes of interest included dementia incidence, dementia subtype, and cognitive testing. Results: On qualitative review, 4/9 studies showed impaired memory, visual motor processing speed, executive function, and verbal testing in previously preeclamptic women. 2/4 studies showed impaired visual motor processing and subjective cognitive complaints in previously eclamptic women. Six cohort studies involving >2.6 million women were included in the meta-analysis. Pooled hazard ratios (aHR) with 95% confidence intervals were generally adjusted for age at delivery ethnicity, and vascular risk factors. Women with a history of gestational hypertension were more likely to develop vascular dementia (aHR 2.02 [1.45-2.83],I2:0%), but not Alzheimer disease (1.24 [0.93-1.66],single-study). Women with a history of preeclampsia were also more likely to develop vascular dementia (2.17 [1.20-3.91],I2:61.1%), but not Alzheimer dementia (1.19 [0.83-1.69],I2:69.9%). Conclusions: Whereas studies of neuropsychological testing in previously preeclamptic and eclamptic women have been heterogeneous, a history of HDP is associated with developing vascular dementia in later life.

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