scholarly journals Multiple functions for the poly(A)-binding protein in mRNA decapping and deadenylation in yeast.

1995 ◽  
Vol 9 (19) ◽  
pp. 2421-2432 ◽  
Author(s):  
G Caponigro ◽  
R Parker
Keyword(s):  
Binding Protein ◽  
Multiple Functions ◽  
Mrna Decapping

scholarly journals Capped mRNA Degradation Intermediates Accumulate in the Yeast spb8-2 Mutant

1998 ◽  
Vol 18 (9) ◽  
pp. 5062-5072 ◽  
Author(s):  
Ronald Boeck ◽  
Bruno Lapeyre ◽  
Christine E. Brown ◽  
Alan B. Sachs
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Family Member ◽  
Gene Deletion ◽  
Binding Protein ◽  
Mrna Degradation ◽  
Protein Family ◽  
Suppressor Mutation ◽  
Mrna Decapping ◽  
Mrna Species ◽  
Degradation Intermediates

ABSTRACT mRNA in the yeast Saccharomyces cerevisiae is primarily degraded through a pathway that is stimulated by removal of the mRNA cap structure. Here we report that a mutation in the SPB8(YJL124c) gene, initially identified as a suppressor mutation of a poly(A)-binding protein (PAB1) gene deletion, stabilizes the mRNA cap structure. Specifically, we find that thespb8-2 mutation results in the accumulation of capped, poly(A)-deficient mRNAs. The presence of this mutation also allows for the detection of mRNA species trimmed from the 3′ end. These data show that this Sm-like protein family member is involved in the process of mRNA decapping, and they provide an example of 3′-5′ mRNA degradation intermediates in yeast.

scholarly journals Multiple Processing Body Factors and the ARE Binding Protein TTP Activate mRNA Decapping

2005 ◽  
Vol 20 (6) ◽  
pp. 905-915 ◽  
Author(s):  
Martin Fenger-Grøn ◽  
Christy Fillman ◽  
Bodil Norrild ◽  
Jens Lykke-Andersen
Keyword(s):  
Binding Protein ◽  
Mrna Decapping ◽  
Processing Body ◽  
Multiple Processing

Multiple functions of an odorant-binding protein in the mosquito Aedes aegypti

2008 ◽  
Vol 372 (3) ◽  
pp. 464-468 ◽  
Author(s):  
Sha Li ◽  
Jean-François Picimbon ◽  
Shidong Ji ◽  
Yunchao Kan ◽  
Qiao Chuanling ◽  
...  
Keyword(s):  
Aedes Aegypti ◽  
Binding Protein ◽  
Odorant Binding Protein ◽  
Multiple Functions ◽  
Odorant Binding

scholarly journals In vivoanalysis of the lumenal binding protein (BiP) reveals multiple functions of its ATPase domain

2007 ◽  
Vol 52 (6) ◽  
pp. 987-1000 ◽  
Author(s):  
Christopher James Snowden ◽  
Nathalie Leborgne-Castel ◽  
Lucie Jan Wootton ◽  
Jane Louise Hadlington ◽  
Jurgen Denecke
Keyword(s):  
Binding Protein ◽  
Atpase Domain ◽  
Multiple Functions

scholarly journals Multiple Functions of the RNA-Binding Protein HuR in Cancer Progression, Treatment Responses and Prognosis

2013 ◽  
Vol 14 (5) ◽  
pp. 10015-10041 ◽  
Author(s):  
Jun Wang ◽  
Yan Guo ◽  
Huili Chu ◽  
Yaping Guan ◽  
Jingwang Bi ◽  
...  
Keyword(s):  
Cancer Progression ◽  
Rna Binding ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Multiple Functions ◽  
Treatment Responses
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