Genes Affecting Early Development in Caenorhabditis elegans

1985 ◽  
Vol 50 (0) ◽  
pp. 69-78 ◽  
Author(s):  
D. Hirsh ◽  
K.J. Kemphues ◽  
D.T. Stinchcomb ◽  
R. Jefferson
1980 ◽  
Vol 74 (2) ◽  
pp. 446-469 ◽  
Author(s):  
William B. Wood ◽  
Ralph Hecht ◽  
Stephen Carr ◽  
Rebecca Vanderslice ◽  
Nurit Wolf ◽  
...  

2006 ◽  
Vol 275 (6) ◽  
pp. 527-539 ◽  
Author(s):  
Marco Gallo ◽  
Allan K. Mah ◽  
Robert C. Johnsen ◽  
Ann M. Rose ◽  
David L. Baillie

2001 ◽  
Vol 356 (1414) ◽  
pp. 1521-1531 ◽  
Author(s):  
Bob Goldstein

The phylum Nematoda serves as an excellent model system for exploring how development evolves, using a comparative approach to developmental genetics. More than 100 laboratories are studying developmental mechanisms in the nematode Caenorhabditis elegans , and many of the methods that have been developed for C. elegans can be applied to other nematodes. This review summarizes what is known so far about steps in early development that have evolved in the nematodes, and proposes potential experiments that could make use of these data to further our understanding of how development evolves. The promise of such a comparative approach to developmental genetics is to fill a wide gap in our understanding of evolution—a gap spanning from mutations in developmental genes through to their phenotypic results, on which natural selection may act.


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