Isoquinolinium 5-(2,4-dinitrophenyl)-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-olate: crystal structure, Hirshfeld surface analysis and pharmacological evaluation
2016 ◽
Vol 72
(4)
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pp. 570-574
Keyword(s):
The asymmetric unit of the title salt C9H8N+·C12H9N4O7−, which exhibits anticonvulsant and hypnotic activities, comprises one anion and one cation interactingviaan N—H...O hydrogen bond. In the anion, the six-membered rings are inclined each to other at 42.78 (9)°. The nitro groups in the 2,4-dinitrophenyl fragment attached to the aromatic ring in theparaandorthopositions are twisted from its plane by 3.1 (2) and 45.5 (2)°, respectively. In the crystal, weak C—H...O hydrogen bonds consolidate the crystal packing. The Hirshfeld surface analysis revealed that O...H/H...O intermolecular contacts predominate in the crystal packing.
2021 ◽
Vol 77
(6)
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pp. 672-676
2020 ◽
Vol 76
(1)
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pp. 111-114
2020 ◽
Vol 76
(7)
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pp. 1033-1037
2018 ◽
Vol 74
(11)
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pp. 1669-1673
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2020 ◽
Vol 76
(11)
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pp. 1794-1798
2021 ◽
Vol 77
(8)
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pp. 834-838
2022 ◽
Vol 78
(1)
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Keyword(s):
2021 ◽
Vol 77
(4)
◽
pp. 412-415