Dietary habits and anthropometric indices among patients with major depressive disorder

2015 ◽  
Vol 45 (2) ◽  
pp. 213-220
Author(s):  
Javad Mohtadinia ◽  
Nasim Abedimanesh ◽  
Solmaz Nomi Golzar ◽  
Mina Analoii

Purpose – This paper aims to determine the comparison between dietary habits and intakes and also anthropometric indices among adult patients with major depressive disorder (MDD) and healthy controls. MDD is a common psychiatric disorder with high prevalence in the world which imposes great economic pressure on the society and also the individual. Nutritional factors affect depressive symptoms by different mechanisms, so dietary modification would be inexpensive and somewhat conceivable. Design/methodology/approach – This pilot case – control study was performed on 30 MDD patients and 30 age- and sex-matched healthy subjects. Demographic and anthropometric characteristics of the patients were recorded. Dietary intake and food habits were assessed by food records and using the food frequency questionnaire, respectively. Variables were compared between two groups using the independent t-test or Mann – Whitney test. Findings – Nutrient intake (except for copper and vitamin D) was significantly higher among healthy subjects when compared to the MDD patients. Daily frequency of food consumption was significantly low among depressed patients in comparison to healthy participants in all seven food groups, except the bread and cereals group. Healthy subjects consumed more fish, about once during two months of a year, while this number was low for MDD patients. Originality/value – The results of this case – control study revealed that dietary habits and consequently micronutrient and macronutrient intakes were significantly different between healthy and MDD patients.

2017 ◽  
Vol 135 (5) ◽  
pp. 469-474 ◽  
Author(s):  
Barbara Schwair Nogueira ◽  
Renerio Fraguas Júnior ◽  
Isabela Martins Benseñor ◽  
Paulo Andrade Lotufo ◽  
Andre Russowsky Brunoni

2015 ◽  
Vol 357 (1-2) ◽  
pp. 19-21 ◽  
Author(s):  
Sandro Zambito Marsala ◽  
Michele Pistacchi ◽  
Pierluigi Tocco ◽  
Manuela Gioulis ◽  
Federico Fabris ◽  
...  

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sanne Roumans ◽  
Kristina Sundquist ◽  
Ashfaque A. Memon ◽  
Anna Hedelius ◽  
Jan Sundquist ◽  
...  

Abstract Background Major depressive disorder (MDD) is one of the most common psychiatric disorders and is a great disease burden. However, its underlying pathophysiology and aetiology remain poorly understood. Available evidence suggests that circulating microRNAs (miRNAs) are associated with MDD, but it is still unknown whether miRNAs can predict subsequent incident MDD. Methods In this nested case-control study, a total of 104 individuals, who were free of MDD at baseline, from the Women’s Health in Lund Area (WHILA) cohort were included. Among them, 52 individuals developed MDD (cases) during the 5 years follow-up and 52 individuals did not develop MDD (controls). Plasma expression levels of miR-17-5p, miR-134-5p, miR-144-5p, let-7b-5p and let-7c-5p at baseline were assessed using qRT-PCR. Logistic regression was used to estimate the odds of developing MDD among individuals with different levels of miRNA expression. Results Plasma expression levels of let-7b-5p were significantly lower (p = 0.02) at baseline in cases compared to controls. After adjustment for age and BMI, let-7b-5p was negatively associated with odds for developing MDD (OR = 0.33, p = 0.03, 95% CI = 0.12–0.91). Moreover, let-7b-5p expression levels showed a trend over time with larger differences between cases and controls for the earlier cases (MDD diagnosis <2 years from baseline) than MDD cases developed later (MDD diagnosis 2–5 years from baseline). Conclusions These findings show that lower plasma levels of let-7b-5p are associated with a higher future risk of MDD. Results need to be validated in a large cohort to examine its potential as a peripheral biomarker for MDD.


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