Machine Learning Based Early Detection of Age-Related Macular Degeneration: Early Warning System

Author(s):  
Deepthi K Prasad ◽  
L Vibha ◽  
K R Venugopal
2021 ◽  
Vol 10 (1) ◽  
pp. 126-134
Author(s):  
Meli Diana ◽  
Dimas Hadi Prayoga ◽  
Dini Prastyo Wijayanti

Background: Hospital service is a process that involves all elements in the hospital including nurses and inpatient rooms or nursing wards. Different inpatient conditions will be treated in separated wards, by the same token patients with unstable conditions are admitted in intensive care units, this procedure aims to reduce the mortality incidence due to sudden cardiac arrest, therefore early detection of patients’ clinical deterioration using the early warning score system performed by the nurse in the nursing wards is required. Objective: This review study is a summary of the early warning system implementation in the nursing wards. Design: The data was obtained from international journal providers Proquest and Ebsco databases. The author accessed unair.remotexs.co website. Review Methods: Narative Review. Results: Early warning score is an effective intervention for emergency detection in patients. Conclusion: Early detection clinical emergency or known as the Early Warning Score System (EWSS) is the application of a scoring system for early detection of patient's condition before a worsening situation occurs. The implementation of this scoring system is necessary due to the high rate of deterioration of patient conditions that requiring immediate management to prevent profound deterioration and its subsequent adverse effect Keywords : Early warning system;nurse care;literatur;review


Author(s):  
Anju Thomas ◽  
P. M. Harikrishnan ◽  
Varun P. Gopi ◽  
P. Palanisamy

Age-related macular degeneration (AMD) is an eye disease that affects the elderly. AMD’s prevalence is increasing as society’s population ages; thus, early detection is critical to prevent vision loss in the elderly. Arrangement of a comprehensive examination of the eye for AMD detection is a challenging task. This paper suggests a new poly scale and dual path (PSDP) convolutional neural network (CNN) architecture for early-stage AMD diagnosis automatically. The proposed PSDP architecture has nine convolutional layers to classify the input image as AMD or normal. A PSDP architecture is used to enhance classification efficiency due to the high variation in size and shape of perforation present in OCT images. The poly scale approach employs filters of various sizes to extract features from local regions more effectively. Simultaneously, the dual path architecture incorporates features extracted from different CNN layers to boost features in the global regions. The sigmoid function is used to classify images into binary categories. The Mendeley data set is used to train the proposed network and tested on Mendeley, Duke, SD-OCT Noor, and OCTID data sets. The testing accuracy of the network in Mendeley, Duke, SD-OCT Noor, and OCT-ID is 99.73%,96.66%,94.89%,99.61%, respectively. The comparison with alternative approaches showed that the proposed algorithm is efficient in detecting AMD. Despite having been trained on the Mendeley data set, the proposed model exhibited good detection accuracy when tested on other data sets. This shows that the suggested model can distinguish AMD/Normal images from various data sets. As compared to other methods, the findings show that the proposed algorithm is efficient at detecting AMD. Rapid eye scanning for early detection of AMD could be possible with the proposed architecture. The proposed CNN can be applied in real-time due to its lower complexity and less learnable parameters.


2019 ◽  
Vol 47 (11) ◽  
pp. 1477-1484 ◽  
Author(s):  
Jennifer C. Ginestra ◽  
Heather M. Giannini ◽  
William D. Schweickert ◽  
Laurie Meadows ◽  
Michael J. Lynch ◽  
...  

2020 ◽  
Vol 41 (6) ◽  
pp. 539-547
Author(s):  
Antonieta Martínez-Velasco ◽  
Andric C. Perez-Ortiz ◽  
Bani Antonio-Aguirre ◽  
Lourdes Martínez-Villaseñor ◽  
Esmeralda Lira-Romero ◽  
...  

2019 ◽  
Vol 9 (24) ◽  
pp. 5550
Author(s):  
Antonieta Martínez-Velasco ◽  
Lourdes Martínez-Villaseñor ◽  
Luis Miralles-Pechuán ◽  
Andric C. Perez-Ortiz ◽  
Juan C. Zenteno ◽  
...  

Age-related macular degeneration (AMD) is the leading cause of visual dysfunction and irreversible blindness in developed countries and a rising cause in underdeveloped countries. There is a current debate on whether or not cataracts are significant risk factors for AMD development. In particular, research regarding this association is so far inconclusive. For this reason, we aimed to employ here a machine-learning approach to analyze the relevance and importance of cataracts as a risk factor for AMD in a large cohort of Hispanics from Mexico. We conducted a nested case control study of 119 cataract cases and 137 healthy unmatched controls focusing on clinical data from electronic medical records. Additionally, we studied two single nucleotide polymorphisms in the CFH gene previously associated with the disease in various populations as positive control for our method. We next determined the most relevant variables and found the bivariate association between cataracts and AMD. Later, we used supervised machine-learning methods to replicate these findings without bias. To improve the interpretability, we detected the five most relevant features and displayed them using a bar graph and a rule-based tree. Our findings suggest that bilateral cataracts are not a significant risk factor for AMD development among Hispanics from Mexico.


JAMA ◽  
2020 ◽  
Vol 324 (8) ◽  
pp. 807
Author(s):  
Bart F. Geerts ◽  
Alexander P. Vlaar ◽  
Denise P. Veelo

2021 ◽  
Vol 7 (1) ◽  
pp. 29-45
Author(s):  
Daehyeon Park ◽  
Jeonghwan Kim ◽  
Doojin Ryu

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