Conventional algorithms such as gradient-based optimization methods usually struggle to deal with high-dimensional non-linear problems and often land up with local minima. Recently developed nature-inspired optimization algorithms are the best approaches for finding global solutions for combinatorial optimization problems like microarray datasets. In this article, a novel hybrid swarm intelligence-based meta-search algorithm is proposed by combining a heuristic method called conditional mutual information maximization with chaos-based firefly algorithm. The combined algorithm is computed in an iterative manner to boost the sharing of information between fireflies, enhancing the search efficiency of chaos-based firefly algorithm and reduces the computational complexities of feature selection. The meta-search model is implemented using a well-established classifier, such as support vector machine as the modeler in a wrapper approach. The chaos-based firefly algorithm increases the global search mobility of fireflies. The efficiency of the model is studied over high-dimensional disease datasets and compared with standard firefly algorithm, particle swarm optimization, and genetic algorithm in the same experimental environment to establish its superiority of feature selection over selected counterparts.
On-demand serum-free media formulations for human hematopoietic cell expansion using a high dimensional search algorithm
