Prediction of Life-Threatening Heart Arrhythmias Using Obstructive Sleep Apnoea Characteristics

Author(s):  
Ghazaleh Mohammad Alinejad ◽  
Seyedramin Rasoulinezhad ◽  
Mohammad Bagher Shamsollahi
1997 ◽  
Vol 111 (12) ◽  
pp. 1151-1154 ◽  
Author(s):  
W. C. Lee ◽  
D. W. Skinner ◽  
A. J. N. Prichard

AbstractA questionnaire was sent to consultant Otolaryngologists (483) throughout the UK to identify any mortality associated with uvulopalatoplasty and other forms of palatoplasties for snoring and/or obstructive sleep apnoea. The response rate was 76.8 per cent (371). Six intra- and post-operative deaths were reported and four were known to have obstructive sleep apnoea. Life-threatening morbidity occurred in at least seven patients (three known apnoeic), two required immediate tracheostomy and two were managed in the intensive care unit. This suggests that the apnoeic patients undergoing palatoplasties experienced significant mortality and morbidity. Pre-operative sleep study should be performed in all snoring patients to identify the apnoeic subgroup. Continuous positive airway pressure, management of excessive obesity, elective tracheostomy and other strategies should be first considered before palatoplasties in these patients.


2021 ◽  
Vol 10 (35) ◽  
pp. 3040-3046
Author(s):  
Nandalal Girijalal Toshniwal ◽  
Shubhangi Amit Mani ◽  
Nilesh Mote ◽  
Ashwini Ramesh Nalkar

Obstructive sleep apnoea (OSA) is a sleep associated breathing disorder and it affects the health and quality of life of individuals suffering from it. Orthodontists should be well aware of the symptoms of this disorder and competent enough to recognize its signs and symptoms. Orthodontics is well suited for the treatment of OSA patients due to their expertise and knowledge regarding growth and development of orofacial and dentofacial structures as well as orthopaedic, orthodontic, and surgical correction of the jaws and other supporting tissues. There are basically two types of sleep apnoea- Central sleep apnoea and obstructive sleep apnoea where obstructive sleep apnoea is the more common one. This disorder can be life threatening as the oxygen supply to various parts of the body is substantially reduced. Obstructive sleep apnoea is caused by an interplay between a variety of factors, including sleep related loss of muscle tone in the tissues supplied by the glossopharyngeal nerve, anatomical obstruction of the nasal passages, large tonsils, large tongue, a retrognathic mandible, obesity, alcohol, sedative medication, and allergies. Sleep apnoea can be caused due to many factors and many treatment modalities have been employed to correct this disorder including mandibular advancement appliances, polysomnographs, and surgical intervention. It can be treated using surgery, continuous positive airway pressure and oral appliances therapy. This article highlights the role the orthodontist plays in the diagnosis and treatment planning of OSA patients. KEY WORDS Orthodontics, Obstructive Sleep Apnoea, Sleep, Snoring


2017 ◽  
Author(s):  
Julie Lynch ◽  
Nikolaos Kyriakakis ◽  
Mark Elliott ◽  
Dipansu Ghosh ◽  
Mitchell Nix ◽  
...  

2020 ◽  
Author(s):  
Mili Dhar ◽  
Jennifer Elias ◽  
Benjamin Field ◽  
Sunil Zachariah ◽  
Julian Emmanuel

2020 ◽  
Author(s):  
Rachel Agius ◽  
Claudia Coelho ◽  
James Crane ◽  
Piya Sen Gupta ◽  
Barbara McGowan

2014 ◽  
Vol 23 (3) ◽  
pp. 291-299 ◽  
Author(s):  
Giovanni Tarantino ◽  
Vincenzo Citro ◽  
Carmine Finelli

Non-alcoholic fatty liver disease (NAFLD) and obstructive sleep apnoea syndrome (OSAS) are common conditions, frequently encountered in patients with obesity and/or metabolic syndrome. NAFLD and OSAS are complex diseases that involve an interaction of several intertwined factors. Several lines of evidence lend credence to an immune system derangement in these patients, i.e. the low grade chronic inflammation status, reckoned to be the most important factor in causing and maintaining these two illnesses. Furthermore, it is emphasized the main role of spleen involvement, as a novel mechanism. In this review the contribution of the visceral adiposity in both NAFLD and OSAS is stressed as well as the role of intermittent hypoxia. Finally, a post on the prevention of systemic inflammation is made.Abbreviations: ALT: alanine aminotransferase; BMI: body mass index; CCR2: chemokine (C-C motif) receptor 2; CRP: C-reactive protein; CPAP: continuous positive airway pressure; FFA: free fatty acid; IGF-I: insulin-like growth factor; IR: insulin resistance; IL-6: interleukin-6; IH: intermittent hypoxia; IKK-β: IκB kinase β; LPS: lipopolysaccharide; MCP-1: monocyte chemoattractant protein-1; NAFLD: non-alcoholic fatty liver disease; NASH: nonalcoholic steatohepatitis; NEFA: non-esterified fatty acid; NF-κB: nuclear factor-κB; OSAS: obstructive sleep apnoea syndrome; PAI-1: plasminogen activator inhibitor-1; ROS: reactive oxygen species; TNF-α: tumor necrosis factor-α; T2D: type 2 diabetes.


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