scholarly journals A Low-Noise Chopper Amplifier Designed for Multi-Channel Neural Signal Acquisition

2019 ◽  
Vol 54 (8) ◽  
pp. 2255-2265 ◽  
Author(s):  
Deng Luo ◽  
Milin Zhang ◽  
Zhihua Wang
Keyword(s):  
Low Noise ◽  
Signal Acquisition ◽  
Neural Signal ◽  
Chopper Amplifier

scholarly journals A FULLY INTEGRATED NEURAL SIGNAL ACQUISITION AMPLIFIER FOR EPILEPTIC SEIZURE PREDICTION

2013 ◽  
pp. 101-106
Author(s):  
M. SANTHANALAKSHMI ◽  
J. ALEXANDER ◽  
P.T. VANATHI ◽  
M. RENUGA
Keyword(s):  
Power Consumption ◽  
Epileptic Seizure ◽  
Low Frequency ◽  
Low Noise ◽  
Signal Acquisition ◽  
Seizure Prediction ◽  
Neural Signal ◽  
Signal Amplifier ◽  
Epileptic Seizure Prediction ◽  
Simulation Results

This paper deals with the design of low power low noise neural signal amplifier for Epileptic Seizure Prediction. The advent of Micro-electro Arrays has driven the need for implantable electronic circuitry to detect those Extracellular neural signals (ENG). We proposed a preamplifier of fully differential Low Noise Amplifier (LNA) with gm boosting in order to enhance the gain as well as reduce the power consumption. Low frequency high pass function has been realized with anti-parallel Diode connected PMOS. Simulation results shows that the input referred noise is 1.24μVrms from 100Hz to 5 KHz, mid-band voltage gain of 44.6dB, and the power consumption is 18.74μw. A new signal processing circuit has been designed extract the seizure onset. The results are validated using Cadence spectre simulator with 180nm technology. Simulation results show that this implantable amplifier is suitable for Epileptic seizure prediction.

CMOS Amplifier for Neural Signal Recording Applications

2015 ◽  
Vol 645-646 ◽  
pp. 1279-1284
Author(s):  
Zhang Zhang ◽  
Zheng Xi Cheng ◽  
Yi Wei Zhuang
Keyword(s):  
Low Noise ◽  
Cmos Process ◽  
Differential Mode ◽  
Neural Signal ◽  
Pass Filter ◽  
Low Pass Filter ◽  
Voltage Range ◽  
Cmos Amplifier ◽  
Signal Recording ◽  
Neural Signal Recording

A low power low noise CMOS amplifier with integrated filter for neural signal recording is designed and fabricated with CSMC 0.5 μm CMOS process. DC offsets introduced by electrode-tissue interface are rejected through a feedback low-pass filter. The bandwidth of the amplifier is in 3.5Hz-5.5KHz range, and the gain is about 48dB in the midband. AC input differential mode voltage range is 10mV, and DC input differential mode voltage range is 180mV. The amplifier can accommodate 180mV DC offsets drift and 10mV neural spikes. The neural probe array is integrated directly on the surface of the amplifier array chip, and is tested in saline solution, and also is implanted in rats in vivo , the results of the experiments show that the amplifier is suitable for neural signal recording. The power dissipation is about 14μW while consuming 0.16 mm2 of chip area, which satisfies implantable devices requirements.

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